{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T00:14:05Z","timestamp":1705623245159},"reference-count":8,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"\n Objective:<\/jats:title>\n Scientific evidence has rarely, if at all, been reported in the literature demonstrating analytical confirmation of the physical compatibility and stability of glycopyrrolate and rocuronium combined. The purpose of this experiment was to determine if glycopyrrolate and rocuronium are physically compatible.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Glycopyrrolate and rocuronium were combined in various containers, observed over a 60-minute period, and compared against positive and negative controls. Measured metrics included color change, precipitate formation, Tyndall beam test, turbidity, and pH. Statistical analyses were used to assess significance of data trends.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The combination of glycopyrrolate and rocuronium did not result in any color change, precipitate formation, a positive Tyndall beam test, or a significantly positive turbidity and did not result in any significant change in pH, regardless of container.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Per the protocol used in this study, glycopyrrolate and rocuronium were determined to be physically compatible.<\/jats:p>\n <\/jats:sec>","DOI":"10.2344\/anpr-69-04-02","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T14:56:30Z","timestamp":1687964190000},"page":"53-57","source":"Crossref","is-referenced-by-count":0,"title":["The Physical Compatibility of Glycopyrrolate and Rocuronium"],"prefix":"10.2344","volume":"70","author":[{"given":"Austen L.","family":"Weeks","sequence":"first","affiliation":[{"name":"*Dentist Anesthesiologist, Graduate of The Ohio State University College of Dentistry Dental Anesthesiology Program, Class of 2021, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Sotos","sequence":"additional","affiliation":[{"name":"\u2020The Ohio State University College of Dentistry, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryce","family":"Woolsey","sequence":"additional","affiliation":[{"name":"\u2021General Practice Resident, The Ohio State University College of Dentistry, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Johnston","sequence":"additional","affiliation":[{"name":"\u00a7Professor Emeritus, The Ohio State University College of Dentistry, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryant W.","family":"Cornelius","sequence":"additional","affiliation":[{"name":"||Assistant Professor and Program Director, of Dental Anesthesiology, The Ohio State University College of Dentistry, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"2023062814560145400_i1878-7177-70-2-53-b01","unstructured":"Cousins\n DH,\n \n \n Upton\n DR.\n \n \n Medication error 79: how to prevent IV medicine errors.\n\t\t\t\t\tPharm Pract.\n\t\t\t\t\t1997;\n\t\t\t\t\t7:\n\t\t\t\t\t310\u2013\n\t\t\t\t\t311."},{"key":"2023062814560145400_i1878-7177-70-2-53-b02","doi-asserted-by":"crossref","unstructured":"Vijayakumar\n A,\n \n \n Sharon\n EV,\n \n \n Teena\n J,\n \n \n Nobil\n S,\n \n \n Nazeer\n I.\n \n \n A clinical study on drug-related problems associated with intravenous drug administration.\n\t\t\t\t\tJ Basic Clin Pharm.\n\t\t\t\t\t2014;\n\t\t\t\t\t5(2):\n\t\t\t\t\t49\u2013\n\t\t\t\t\t53.","DOI":"10.4103\/0976-0105.134984"},{"key":"2023062814560145400_i1878-7177-70-2-53-b03","doi-asserted-by":"crossref","unstructured":"Khan\n S,\n \n \n Stannard\n N,\n \n \n Greijn\n J.\n \n \n Precipitation of thiopental with some muscle relaxants: a potential hazard.\n\t\t\t\t\tJRSM Short Reports.\n\t\t\t\t\t2011;\n\t\t\t\t\t2:\n\t\t\t\t\t1\u2013\n\t\t\t\t\t2.","DOI":"10.1258\/shorts.2011.011031"},{"key":"2023062814560145400_i1878-7177-70-2-53-b04","unstructured":"Trissel\n LA.\n \n \n \n Rocuronium Bromide Compatibility With Selected Injections. Compatibility Data. Vol. 5. \n\t\t\t\t\tKennesaw, GA: TriPharma;\n\t\t\t\t\t2008."},{"key":"2023062814560145400_i1878-7177-70-2-53-b05","doi-asserted-by":"crossref","unstructured":"Abdelkader\n A,\n \n \n Fathi\n HA,\n \n \n Hamed\n MA,\n \n \n Elsabahy\n M.\n \n \n Nanomedicine: a new paradigm to overcome drug incompatibilities.\n\t\t\t\t\tPharm Pharmacol.\n\t\t\t\t\t2020;\n\t\t\t\t\t72:\n\t\t\t\t\t1289\u2013\n\t\t\t\t\t1305.","DOI":"10.1111\/jphp.13292"},{"key":"2023062814560145400_i1878-7177-70-2-53-b06","doi-asserted-by":"crossref","unstructured":"Hanifah\n S,\n \n \n Nugroho\n B,\n \n \n Chabib\n L.\n \n \n Compatibility of acetaminophen with central nervous system medications during simulated Y-site injection.\n\t\t\t\t\tAnaesthesiol Intensive Care.\n\t\t\t\t\t2019;\n\t\t\t\t\t52(1):\n\t\t\t\t\t23\u2013\n\t\t\t\t\t27.","DOI":"10.5114\/ait.2020.92684"},{"key":"2023062814560145400_i1878-7177-70-2-53-b07","doi-asserted-by":"crossref","unstructured":"Staven\n V,\n \n \n Wang\n S,\n \n \n Gr\u00f8nlie\n I,\n \n \n Tho\n I.\n \n \n Development and evaluation of a test program for Y-site compatibility testing of total parenteral nutrition and intravenous drugs.\n\t\t\t\t\tNutr J.\n\t\t\t\t\t2016;\n\t\t\t\t\t15:\n\t\t\t\t\t29.","DOI":"10.1186\/s12937-016-0149-x"},{"key":"2023062814560145400_i1878-7177-70-2-53-b08","unstructured":"Trusley\n C,\n \n \n Ben\n M,\n \n \n Kupiec\n TC,\n \n \n Trissel\n LA.\n \n \n Compatibility and stability of palonosetron hydrochloride with four neuromuscular blocking agents during simulated y-site administration.\n\t\t\t\t\tInt J Pharm Compd.\n\t\t\t\t\t2008;\n\t\t\t\t\t12(2):\n\t\t\t\t\t156\u2013\n\t\t\t\t\t160."}],"container-title":["Anesthesia Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/70\/2\/53\/3230218\/i1878-7177-70-2-53.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/70\/2\/53\/3230218\/i1878-7177-70-2-53.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T19:51:21Z","timestamp":1705607481000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/70\/2\/article-p53.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6,28]]},"published-print":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.2344\/anpr-69-04-02","relation":{},"ISSN":["1878-7177","0003-3006"],"issn-type":[{"value":"1878-7177","type":"electronic"},{"value":"0003-3006","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,1]]}}}