{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T03:02:36Z","timestamp":1779850956847,"version":"3.53.1"},"reference-count":36,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>Pulmonary hypertension is characterized by higher-than-normal pulmonary arterial pressures. This case report describes the perioperative management of a male patient with idiopathic pulmonary hypertension and a history of vasovagal syncope during previous dental extractions with local anesthesia. He underwent successful extraction of a single tooth with intravenous moderate sedation using dexmedetomidine and midazolam as well as prilocaine with felypressin for local anesthesia. There are many considerations surrounding the anesthetic management of patients with pulmonary hypertension, including the need to maintain systemic blood pressure, avoid hypoxemia and hypercapnia, and ensure adequate analgesia.<\/jats:p>","DOI":"10.2344\/anpr-70-03-08","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T08:42:42Z","timestamp":1715244162000},"page":"29-33","source":"Crossref","is-referenced-by-count":1,"title":["Perioperative Management of a Patient With Idiopathic Pulmonary Hypertension and a History of Syncope: A Case Report"],"prefix":"10.2344","volume":"71","author":[{"given":"Aiji","family":"Sato (Boku)","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Anesthesiology, Aichi Gakuin University School of Dentistry, Nagoya, Japan"},{"name":"Associate Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MinHye","family":"So","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuma","family":"Fujikake","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoshi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Kamimura","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruko","family":"Ota","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomomi","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Resident, Department of Oral and Maxillofacial Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Oral and Maxillofacial Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Shibuya","sequence":"additional","affiliation":[{"name":"Professor, Department of Oral and Maxillofacial Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuya","family":"Sobue","sequence":"additional","affiliation":[{"name":"Professor, Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","reference":[{"key":"r1","series-title":"Ann Transl Med.","first-page":"355","article-title":"Anesthetic management during bronchoscopy of patients with pulmonary hypertension","volume":"7","author":"Broker J,","year":"2019","unstructured":"Broker J, Cvetkovic D, Yaghoubian S. 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Risk assessment, prognosis and guideline implementation in pulmonary arterial hypertension. Eur Respir J. 2017; 50:1700889."},{"key":"r4","series-title":"Intern Med","first-page":"12","article-title":"Prediction of life expectancy in patients with primary pulmonary hypertension: a retrospective nationwide survey from 1980-1990","volume":"38","author":"Okada O,","year":"1999","unstructured":"Okada O, Tanabe N, Yasuda J, . Prediction of life expectancy in patients with primary pulmonary hypertension: a retrospective nationwide survey from 1980-1990. Intern Med. 1999; 38:12\u201316."},{"key":"r5","series-title":"Circ J.","first-page":"275","article-title":"Effectiveness and outcome of pulmonary arterial hypertension-specific therapy in Japanese patients with pulmonary arterial hypertension","volume":"82","author":"Tamura Y,","year":"2017","unstructured":"Tamura Y, Kumamaru H, Satoh T, . 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J Oral Maxillofac Surg. 2019; 77:29\u201341."},{"key":"r9","series-title":"Biomed Res Int.","first-page":"2807581","article-title":"Usefulness of continuous low-dose fentanyl in combination with dexmedetomidine and midazolam for intravenous sedation: a randomised controlled trial","volume":"2022","author":"Okumura Y,","year":"2022","unstructured":"Okumura Y, Sato (Boku) A Tachi N, . Usefulness of continuous low-dose fentanyl in combination with dexmedetomidine and midazolam for intravenous sedation: a randomised controlled trial. Biomed Res Int. 2022; 2022:2807581."},{"key":"r10","series-title":"Anesth Analg","first-page":"793","article-title":"The effect of midazolam on left ventricular pump performance and contractility in anesthetized patients with coronary artery disease: effect of preoperative ejection fraction","volume":"81","author":"Messina AG,","year":"1995","unstructured":"Messina AG, Paranicas M, Yao FS, . 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