{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:51:13Z","timestamp":1778629873561,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:p>Primary uveal-tract neoplasms are extremely rare in childhood; the most common lesions found are melanocytic. We report here the case of a 7-year-old girl who underwent enucleation of the right eye with clinical suspicion of choroid melanoma as a result of a ciliary body mass that extended to the posterior chamber. Histologically, the neoplasm featured spindle cell morphology, atypia, and mitoses. The tumor expressed smooth muscle \u03b1 actin, pan-actin HHF-35, and desmin, whereas immunohistochemistry for melanocytic markers, such as S-100, Melan-A, and HMB-45, was negative. Based on these features, the diagnosis of leiomyosarcoma of the ciliary body was firmly established. Although several leiomyomas have been reported in the literature, there are only 2 previously reported cases of primary leiomyosarcoma of the uveal tract. Immunohistochemical expression of muscle proteins allowed distinction from the most common melanocytic tumors arising in this location.<\/jats:p>","DOI":"10.2350\/07-02-0231.1","type":"journal-article","created":{"date-parts":[[2009,1,13]],"date-time":"2009-01-13T11:25:50Z","timestamp":1231845950000},"page":"479-481","source":"Crossref","is-referenced-by-count":13,"title":["Unusual Primary Ocular Neoplasm in a Child: Leiomyosarcoma of the Ciliary Body"],"prefix":"10.1177","volume":"11","author":[{"given":"Mariana M.","family":"Cajaiba","sequence":"first","affiliation":[{"name":"Department of Anatomic Pathology, Hospital do C\u00e2ncer AC Camargo\u2014S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha M.","family":"Chojniak","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital do C\u00e2ncer AC Camargo\u2014S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela W.","family":"Cunha","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology, Hospital do C\u00e2ncer AC Camargo\u2014S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9,1]]},"reference":[{"key":"bibr1-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2003.08.001"},{"key":"bibr2-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197705)39:5<2102::AID-CNCR2820390527>3.0.CO;2-D"},{"key":"bibr3-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00407842"},{"key":"bibr4-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(82)34657-6"},{"key":"bibr5-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1985.01050110105037"},{"key":"bibr6-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02169778"},{"key":"bibr7-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1994.01090160097028"},{"key":"bibr8-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.1999.770622.x"},{"key":"bibr9-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1177\/106689690201000413"},{"key":"bibr10-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2004.01628.x"},{"key":"bibr11-07-02-0231.1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3928\/0191-3913-19901101-11","volume":"27","author":"Yu DY","year":"1990","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"bibr12-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(13)31239-1"},{"key":"bibr13-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.56.4.366"},{"key":"bibr14-07-02-0231.1","first-page":"1765","volume":"24","author":"Park SW","year":"2003","journal-title":"Am J Neuroradiol"},{"key":"bibr15-07-02-0231.1","first-page":"123","volume":"105","author":"Beebe DC","year":"1986","journal-title":"Trans Ophthalmol Soc UK"},{"key":"bibr16-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1159\/000082287"},{"key":"bibr17-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.3109\/01913129709016372"},{"key":"bibr18-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.07.023"},{"key":"bibr19-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(99)00114-9"},{"key":"bibr20-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.1159\/000309573"},{"key":"bibr21-07-02-0231.1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2003.18.4.614"}],"container-title":["Pediatric and Developmental Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2350\/07-02-0231.1","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2350\/07-02-0231.1","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2350\/07-02-0231.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:35:33Z","timestamp":1777602933000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2350\/07-02-0231.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["10.2350\/07-02-0231.1"],"URL":"https:\/\/doi.org\/10.2350\/07-02-0231.1","relation":{},"ISSN":["1093-5266","1615-5742"],"issn-type":[{"value":"1093-5266","type":"print"},{"value":"1615-5742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}