{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:36:59Z","timestamp":1789951019770,"version":"4.0.1"},"reference-count":43,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p>Meckel-Gruber syndrome (MKS) is a fatal, autosomal recessive disorder characterized by malformation of central nervous system, particularly occipital encephalocele, bilateral renal dysplasia, and polydactyly. However, the clinical findings of this syndrome encompass various organ abnormalities as a result of genetic heterogeneity. The associated heart anomaly in MKS is inconstant. Its prevalence is rare and no striking or specific cardiac defects have been documented. We present a case of MKS with combined cor triatriatum sinistrum (left atrium divided into upper and lower compartment by a thin membrane) and hypoplastic left heart syndrome (underdeveloped mitral valve, left ventricle, and aorta) in a 33-week male fetus that was ultrasonographically detected and confirmed by autopsy. In addition to the cardiac defects, the patient was found to have postaxial polydactyly of 4 extremities, Dandy-Walker malformation, bilateral renal cystic dysplasia, and hepatic plate malformation. To the best of our knowledge, this is the first time that a combination of cor triatriatum sinistrum and hypoplastic left heart syndrome in MKS has been reported in the literature.<\/jats:p>","DOI":"10.2350\/09-02-0614-cr.1","type":"journal-article","created":{"date-parts":[[2009,4,9]],"date-time":"2009-04-09T15:30:34Z","timestamp":1239291034000},"page":"404-409","source":"Crossref","is-referenced-by-count":6,"title":["Combination of Cor Triatriatum Sinistrum and Hypoplastic Left Heart Syndrome in Meckel-Gruber Syndrome: A Case Report"],"prefix":"10.1177","volume":"12","author":[{"given":"Mana","family":"Taweevisit","sequence":"first","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Chulalongkorn University, 1873 King Rama IV Street, Pathumwan, Bangkok, 10330 Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitsupa","family":"Treetipsatit","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, 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