{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:52:53Z","timestamp":1777884773360,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>Developmental anomalies resulting in a single eye (cyclopia) or fusion of the eyes (synophthalmia) are rare. Examples of unilateral synophthalmia\u2014in which there are 1 normal and 2 fused eyes from 3 anlagen in 2 orbits, 1 lateral proboscis, and 3 optic nerves\u2014are even more rare. Herein, I report a unique fetus with unilateral synophthalmia that was not associated with a lateral proboscis but instead had an extra cerebral hemisphere. I postulate that the unilateral synophthalmia, accessory cerebral hemisphere, and minor structural abnormalities in the skull base were the result of failure in separating a monozygous twin, a situation similar to that postulated as the cause of fetus in fetu.<\/jats:p>","DOI":"10.2350\/10-03-0809-cr.1","type":"journal-article","created":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T08:25:54Z","timestamp":1275985554000},"page":"130-133","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Unique Case of Unilateral Synophthalmia"],"prefix":"10.1177","volume":"14","author":[{"given":"Alan D.","family":"Proia","sequence":"first","affiliation":[{"name":"Department of Pathology, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,11,1]]},"reference":[{"key":"bibr1-10-03-0809-CR.1","first-page":"415","volume-title":"System of Ophthalmology","volume":"3","author":"Duke-Elder S","year":"1963"},{"key":"bibr2-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00158252"},{"key":"bibr3-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00230088"},{"key":"bibr4-10-03-0809-CR.1","first-page":"505","volume":"75","author":"Howard RO","year":"1977","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr5-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20048"},{"key":"bibr6-10-03-0809-CR.1","first-page":"132","volume-title":"The Borderline of Embryology and Pathology","author":"Willis RA","year":"1962","edition":"2"},{"key":"bibr7-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.3928\/0191-3913-19810701-07"},{"key":"bibr8-10-03-0809-CR.1","first-page":"22","volume-title":"Ophthalmology","author":"Azar NF","year":"2004","edition":"2"},{"key":"bibr9-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.2.177"},{"key":"bibr10-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1947.00900010164003"},{"key":"bibr11-10-03-0809-CR.1","first-page":"313","volume":"34","author":"Salorio MS","year":"1974","journal-title":"Arch Soc Esp Oftalmol"},{"key":"bibr12-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.3928\/0191-3913-19890301-13"},{"key":"bibr13-10-03-0809-CR.1","volume-title":"Developmental Anatomy. A Textbook and Laboratory Manual of Embryology","author":"Arey LB","year":"1965","edition":"7"},{"key":"bibr14-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.6.1335"},{"key":"bibr15-10-03-0809-CR.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2004.10.009"}],"container-title":["Pediatric and Developmental Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2350\/10-03-0809-CR.1","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2350\/10-03-0809-CR.1","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2350\/10-03-0809-CR.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:37:48Z","timestamp":1777603068000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2350\/10-03-0809-CR.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.2350\/10-03-0809-CR.1"],"URL":"https:\/\/doi.org\/10.2350\/10-03-0809-cr.1","relation":{},"ISSN":["1093-5266","1615-5742"],"issn-type":[{"value":"1093-5266","type":"print"},{"value":"1615-5742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}