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However, because the diagnosis of the lethal GSDs relies heavily upon radiologic examination of fetal remains, reaching an accurate diagnosis in this setting can be challenging. We report an autopsy case of a fetus delivered by D&amp;E at 15 4\/7 weeks gestation with radiologic, histologic, and genetic findings compatible with achondrogenesis type 2 and discuss an evidence-based differential diagnostic approach to lethal GSDs terminated by early midtrimester D&amp;E.<\/jats:p>","DOI":"10.2350\/13-02-1305-oa.1","type":"journal-article","created":{"date-parts":[[2013,10,21]],"date-time":"2013-10-21T15:38:27Z","timestamp":1382369907000},"page":"10-20","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pathologic Diagnosis of Achondrogenesis Type 2 in a Fragmented Fetus: Case Report and Evidence-Based Differential Diagnostic Approach in the Early Midtrimester"],"prefix":"10.1177","volume":"17","author":[{"given":"Paul S.","family":"Weisman","sequence":"first","affiliation":[{"name":"Department of Pathology, Northwestern Memorial Hospital, Northwestern University Feinberg School of 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