{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:59:11Z","timestamp":1790258351311,"version":"4.1.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:p>Teratoid hepatoblastoma is a rare histological subtype of hepatoblastoma. A 15-month-old girl with full trisomy 13 presented with a liver mass (6 \u00d7 4.4 \u00d7 3.4 cm). Histological examination showed a teratoid hepatoblastoma with very different differentiation patterns intermixed with each other. Approximately 30% of the tumor demonstrated a primitive glandular epithelium component, which had a moderate to well-differentiated adenocarcinoma-like morphology, and features of mucinous epithelium with a biliary immunophenotype. We designated it as cholangioblastic component. The child received 4 cycles of monotherapy with doxorubicin after complete resection and showed no evidence of residual tumor 8 months after surgery. Our case is not only the 1st report of hepatoblastoma in trisomy 13 but also represents a unique example with a large glandular epithelium component with cholangioblastic features. Increased awareness of this entity and further molecular studies are needed for better understanding of the pathogenesis of teratoid hepatoblastoma.<\/jats:p>","DOI":"10.2350\/13-06-1348-cr.1","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T16:34:26Z","timestamp":1375979666000},"page":"438-441","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Teratoid Hepatoblastoma with Abundant Cholangioblastic Component in a Child with Full Trisomy 13"],"prefix":"10.1177","volume":"16","author":[{"given":"Shengmei","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA, 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,11,1]]},"reference":[{"key":"bibr1-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70008-3"},{"key":"bibr2-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320430621"},{"key":"bibr3-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.4076\/1752-1947-3-8319"},{"key":"bibr4-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2011.03528.x"},{"key":"bibr5-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0212-CR"},{"key":"bibr6-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1080\/15513810802448100"},{"key":"bibr7-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.3109\/15513815.2012.721481"},{"key":"bibr8-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.10173"},{"key":"bibr9-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2007.06.006"},{"key":"bibr10-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2005.12.015"},{"key":"bibr11-13-06-1348-CR.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0571-8"},{"key":"bibr12-13-06-1348-CR.1","first-page":"288","volume":"3","author":"Duarte 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