{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:16:13Z","timestamp":1789870573032,"version":"4.0.1"},"reference-count":70,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.2353\/ajpath.2007.061245","type":"journal-article","created":{"date-parts":[[2007,8,17]],"date-time":"2007-08-17T00:40:24Z","timestamp":1187311224000},"page":"1237-1248","source":"Crossref","is-referenced-by-count":21,"title":["Aberrant Mucosal Mast Cell Protease Expression in the Enteric Epithelium of Nematode-Infected Mice Lacking the Integrin \u03b1v\u03b26, a Transforming Growth Factor-\u03b21 Activator"],"prefix":"10.1016","volume":"171","author":[{"given":"Pamela A.","family":"Knight","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy K.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven H.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth M.","family":"Thornton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith A.","family":"Pate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh R.P.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.2353\/ajpath.2007.061245_bib1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1084\/jem.190.7.953","article-title":"Tumor necrosis factor alpha is a critical component of interleukin 13-mediated protective T helper cell type 2 responses during helminth infection","volume":"190","author":"Artis","year":"1999","journal-title":"J Exp Med"},{"key":"10.2353\/ajpath.2007.061245_bib2","first-page":"40","article-title":"Roles of mucosal mast cells in intestinal cell mediated immunity","volume":"59","author":"Ferguson","year":"1987","journal-title":"Ann Allergy"},{"key":"10.2353\/ajpath.2007.061245_bib3","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0165-2427(96)05696-6","article-title":"Mucosal mast cells and the allergic response against nematode parasites","volume":"54","author":"Miller","year":"1996","journal-title":"Vet Immunol Immunopathol"},{"key":"10.2353\/ajpath.2007.061245_bib4","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1128\/IAI.41.1.445-447.1983","article-title":"Delayed expulsion of adult Trichinella spiralis by mast cell-deficient W\/Wv mice","volume":"41","author":"Ha","year":"1983","journal-title":"Infect Immun"},{"key":"10.2353\/ajpath.2007.061245_bib5","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1002\/eji.1830271011","article-title":"Interleukin-9 is involved in host protective immunity to intestinal nematode infection","volume":"27","author":"Faulkner","year":"1997","journal-title":"Eur J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-3024.1983.tb00718.x","article-title":"Kinetics of expulsion of the nematode, Nippostrongylus brasiliensis, in mast-cell-deficient W\/WV mice","volume":"5","author":"Mitchell","year":"1983","journal-title":"Parasite Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-3024.1994.tb00358.x","article-title":"Selective effector mechanisms for the expulsion of intestinal helminths","volume":"16","author":"Nawa","year":"1994","journal-title":"Parasite Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib8","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1084\/jem.192.12.1849","article-title":"Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1","volume":"192","author":"Knight","year":"2000","journal-title":"J Exp Med"},{"key":"10.2353\/ajpath.2007.061245_bib9","doi-asserted-by":"crossref","first-page":"7761","DOI":"10.1073\/pnas.1231488100","article-title":"Mast cells disrupt epithelial barrier function during enteric nematode infection","volume":"100","author":"McDermott","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2007.061245_bib10","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1084\/jem.182.6.1871","article-title":"Release of the mucosal mast cell granule chymase, rat mast cell protease-II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum","volume":"182","author":"Scudamore","year":"1995","journal-title":"J Exp Med"},{"key":"10.2353\/ajpath.2007.061245_bib11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1053\/j.gastro.2004.04.004","article-title":"Mouse mast cell protease-1 is required for the enteropathy induced by gastrointestinal helminth infection in the mouse","volume":"127","author":"Lawrence","year":"2004","journal-title":"Gastroenterology"},{"key":"10.2353\/ajpath.2007.061245_bib12","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1182\/blood.V93.10.3473.410k01_3473_3486","article-title":"A novel function for transforming growth factor-\u03b21: upregulation of the expression and the IgE-independent extracellular release of a mucosal mast cell granule-specific \u03b2-chymase, mouse mast cell protease-1","volume":"93","author":"Miller","year":"1999","journal-title":"Blood"},{"key":"10.2353\/ajpath.2007.061245_bib13","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1046\/j.1365-2222.2003.01571.x","article-title":"Constitutive secretion of the granule chymase mouse mast cell protease-1 and the chemokine, CCL2, by mucosal mast cell homologues","volume":"33","author":"Brown","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"10.2353\/ajpath.2007.061245_bib14","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1046\/j.1365-2222.2002.01233.x","article-title":"Transforming growth factor-beta1 mediates coexpression of the integrin subunit alphaE and the chymase mouse mast cell protease-1 during the early differentiation of bone marrow-derived mucosal mast cell homologues","volume":"32","author":"Wright","year":"2002","journal-title":"Clin Exp Allergy"},{"key":"10.2353\/ajpath.2007.061245_bib15","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/pmic.200500211","article-title":"The proteome of mouse mucosal mast cell homologues: the role of transforming growth factor \u03b21","volume":"6","author":"Pemberton","year":"2006","journal-title":"Proteomics"},{"key":"10.2353\/ajpath.2007.061245_bib16","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/jlb.67.3.350","article-title":"Human mast cell migration in response to members of the transforming growth factor-\u03b2 family","volume":"67","author":"Olsson","year":"2000","journal-title":"J Leukoc Biol"},{"key":"10.2353\/ajpath.2007.061245_bib17","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S0002-9440(10)63853-9","article-title":"Transforming growth factor-\u03b2 mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells","volume":"162","author":"Beck","year":"2003","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2007.061245_bib18","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/BF01213309","article-title":"Healing the epithelium: solving the problem from two sides","volume":"32","author":"Podolsky","year":"1997","journal-title":"J Gastroenterol"},{"key":"10.2353\/ajpath.2007.061245_bib19","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1053\/gast.2001.22432a","article-title":"Murine ileitis after intracellular parasite infection is controlled by TGF-\u03b2-producing intraepithelial lymphocytes","volume":"120","author":"Buzoni-Gatel","year":"2001","journal-title":"Gastroenterology"},{"key":"10.2353\/ajpath.2007.061245_bib20","doi-asserted-by":"crossref","first-page":"5635","DOI":"10.1128\/IAI.68.10.5635-5644.2000","article-title":"Transforming growth factor beta1 ameliorates intestinal epithelial barrier disruption by Cryptosporidium parvum in vitro in the absence of mucosal T lymphocytes","volume":"68","author":"Roche","year":"2000","journal-title":"Infect Immun"},{"key":"10.2353\/ajpath.2007.061245_bib21","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1093\/emboj\/18.5.1280","article-title":"Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-\u03b2","volume":"18","author":"Yang","year":"1999","journal-title":"EMBO J"},{"key":"10.2353\/ajpath.2007.061245_bib22","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1136\/gut.49.2.190","article-title":"Loss of transforming growth factor \u03b2 signalling in the intestine contributes to tissue injury in inflammatory bowel disease","volume":"49","author":"Hahm","year":"2001","journal-title":"Gut"},{"issue":"Suppl 2","key":"10.2353\/ajpath.2007.061245_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1046\/j.1365-2036.16.s2.3.x","article-title":"Conditional loss of TGF-\u03b2 signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice","volume":"16","author":"Hahm","year":"2002","journal-title":"Aliment Pharmacol Ther"},{"key":"10.2353\/ajpath.2007.061245_bib24","series-title":"Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines","first-page":"113","article-title":"Effector and regulatory lymphoid cells and cytokines in mucosal sites","author":"MacDonald","year":"1999"},{"key":"10.2353\/ajpath.2007.061245_bib25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1242\/jcs.00229","article-title":"Making sense of latent TGF\u03b2 activation","volume":"116","author":"Annes","year":"2003","journal-title":"J Cell Sci"},{"key":"10.2353\/ajpath.2007.061245_bib26","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.200109100","article-title":"The integrin \u03b1v\u03b28 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-\u03b21","volume":"157","author":"Mu","year":"2002","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.061245_bib27","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0092-8674(00)81460-9","article-title":"Thrombospondin-1 is a major activator of TGF-\u03b21 in vivo","volume":"93","author":"Crawford","year":"1998","journal-title":"Cell"},{"key":"10.2353\/ajpath.2007.061245_bib28","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1083\/jcb.133.4.921","article-title":"Inactivation of the integrin \u03b26 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lungs and skin","volume":"133","author":"Huang","year":"1996","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.061245_bib29","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1582-4934.2005.tb00367.x","article-title":"Characterization of integrin \u03b26 and thrombospondin-1 double-null mice","volume":"9","author":"Ludlow","year":"2005","journal-title":"J Cell Mol Med"},{"key":"10.2353\/ajpath.2007.061245_bib30","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1177\/41.10.8245410","article-title":"Restricted distribution of integrin beta-6 messenger-RNA in primate epithelial tissues","volume":"41","author":"Breuss","year":"1993","journal-title":"J Histochem Cytochem"},{"key":"10.2353\/ajpath.2007.061245_bib31","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1369\/jhc.5A6854.2006","article-title":"Integrin-alpha(v) beta(6), a putative receptor for foot-and-mouth disease virus, is constitutively expressed in ruminant airways","volume":"54","author":"Brown","year":"2006","journal-title":"J Histochem Cytochem"},{"key":"10.2353\/ajpath.2007.061245_bib32","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0002-9440(10)64236-8","article-title":"Enteric expression of the integrin is essential for nematode-induced mucosal mast cell hyperplasia and expression of the granule chymase, mouse mast cell protease-1","volume":"161","author":"Knight","year":"2002","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2007.061245_bib33","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0092-8674(00)80545-0","article-title":"The integrin \u03b1v\u03b26 binds and activates latent TGF \u03b21: a mechanism for regulating pulmonary inflammation and fibrosis","volume":"96","author":"Munger","year":"1999","journal-title":"Cell"},{"key":"10.2353\/ajpath.2007.061245_bib34","first-page":"964","article-title":"Inactivation of the \u03b26 integrin subunit gene protects against bleomycin-induced pulmonary fibrosis","volume":"7","author":"Griffiths","year":"1996","journal-title":"Mol Biol Cell"},{"key":"10.2353\/ajpath.2007.061245_bib35","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1165\/ajrcmb.19.4.3293","article-title":"Expression of the human integrin \u03b26 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in \u03b26 knockout mice","volume":"19","author":"Huang","year":"1998","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.2353\/ajpath.2007.061245_bib36","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0002-9440(10)63278-6","article-title":"Expression of integrin-alpha(E) by mucosal mast cells in the intestinal epithelium and its absence in nematode-infected mice lacking the transforming growth-factor-beta(1)-activating integrin alpha(v)beta(6)","volume":"165","author":"Brown","year":"2004","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2007.061245_bib37","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/intimm\/8.4.559","article-title":"A critical role for stem cell factor and c-kit in host protective immunity to an intestinal helminth","volume":"8","author":"Donaldson","year":"1996","journal-title":"Int Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib38","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-3024.1993.tb00572.x","article-title":"The in vivo role of stem-cell factor (c-Kit ligand) on mastocytosis and host protective immunity to the intestinal nematode Trichinella spiralis in mice","volume":"15","author":"Grencis","year":"1993","journal-title":"Parasite Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib39","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.0141-9838.2001.00437.x","article-title":"Chemokine and cytokine expression in murine intestinal epithelium following Nippostrongylus brasiliensis infection","volume":"24","author":"Rosbottom","year":"2002","journal-title":"Parasite Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib40","doi-asserted-by":"crossref","first-page":"6076","DOI":"10.1128\/IAI.72.10.6076-6086.2004","article-title":"Expression profiling reveals novel innate and inflammatory responses in the jejunal epithelial compartment during infection with Trichinella spiralis","volume":"72","author":"Knight","year":"2004","journal-title":"Infect Immun"},{"key":"10.2353\/ajpath.2007.061245_bib41","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0002-9440(10)65592-7","article-title":"Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the \u03b2-chymase, mouse mast cell protease-1","volume":"153","author":"Wastling","year":"1998","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2007.061245_bib42","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1046\/j.1365-2222.2003.01720.x","article-title":"Purification and characterization of mouse mast cell proteinase-2 and the differential expression and release of mouse mast cell proteinase-1 and -2 in vivo","volume":"33","author":"Pemberton","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"10.2353\/ajpath.2007.061245_bib43","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1079\/JOH2002160","article-title":"Mucosal mast cells and nematode infection: strain-specific differences in mast cell precursor frequency revisited","volume":"77","author":"Brown","year":"2003","journal-title":"J Helminthol"},{"key":"10.2353\/ajpath.2007.061245_bib44","doi-asserted-by":"crossref","first-page":"29158","DOI":"10.1074\/jbc.272.46.29158","article-title":"Mouse mast cell protease 9, a novel member of the chromosome 14 family of serine proteases that is selectively expressed in uterine mast cells","volume":"272","author":"Hunt","year":"1997","journal-title":"J Biol Chem"},{"key":"10.2353\/ajpath.2007.061245_bib45","doi-asserted-by":"crossref","first-page":"5537","DOI":"10.4049\/jimmunol.160.11.5537","article-title":"Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis","volume":"160","author":"Friend","year":"1998","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib46","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1084\/jem.20042407","article-title":"Leukotriene B-4, an activation product of mast cells, is a chemoattractant for their progenitors","volume":"201","author":"Weller","year":"2005","journal-title":"J Exp Med"},{"key":"10.2353\/ajpath.2007.061245_bib47","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/87749","article-title":"gp49BI-\u03b1v\u03b23 interaction inhibits antigen-induced mast cell activation","volume":"2","author":"Castells","year":"2001","journal-title":"Nat Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib48","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1182\/blood-2003-09-3146","article-title":"In vivo exit of c-kit+\/CD49dhi\/\u03b27+ mucosal mast cell precursors from the bone marrow following infection with the intestinal nematode Trichinella spiralis","volume":"103","author":"Pennock","year":"2004","journal-title":"Blood"},{"key":"10.2353\/ajpath.2007.061245_bib49","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1084\/jem.184.1.271","article-title":"A role for stem cell factor (SCF): c-kit interaction(s) in the intestinal tract response to Salmonella typhimurium infection","volume":"184","author":"Klimpel","year":"1996","journal-title":"J Exp Med"},{"key":"10.2353\/ajpath.2007.061245_bib50","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.4049\/jimmunol.169.5.2553","article-title":"IL-18 regulates intestinal mastocytosis and Th2 cytokine production independently of IFN-gamma during Trichinella spiralis infection","volume":"169","author":"Helmby","year":"2002","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib51","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.4049\/jimmunol.175.5.3207","article-title":"Intraepithelial NK cell-derived IL-13 induces intestinal pathology associated with nematode infection","volume":"175","author":"McDermott","year":"2005","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib52","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.4049\/jimmunol.164.4.2046","article-title":"Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism","volume":"164","author":"Urban","year":"2000","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib53","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1067\/mai.2001.114989","article-title":"The other side of the coin: the protective role of the T(H)2 cytokines","volume":"107","author":"Finkelman","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib54","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0304-4017(01)00482-4","article-title":"Cytokine regulation of resistance and susceptibility to intestinal nematode infection\u2014from host to parasite","volume":"100","author":"Grencis","year":"2001","journal-title":"Vet Parasitol"},{"key":"10.2353\/ajpath.2007.061245_bib55","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1006\/clin.1998.4586","article-title":"Regulation of human lymphocyte IL-4 secretion by intestinal epithelial cell-derived interleukin-7 and transforming growth factor-\u03b2","volume":"88","author":"Jiang","year":"1998","journal-title":"Clin Immunol Immunopathol"},{"key":"10.2353\/ajpath.2007.061245_bib56","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4049\/jimmunol.159.1.117","article-title":"TGF-\u03b2 down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors","volume":"159","author":"Tang","year":"1997","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib57","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.0105-2896.2004.00192.x","article-title":"Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites","volume":"201","author":"Finkelman","year":"2004","journal-title":"Immunol Rev"},{"key":"10.2353\/ajpath.2007.061245_bib58","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1365-3024.2001.00353.x","article-title":"Stat6 dependent goblet cell hyperplasia during intestinal nematode infection","volume":"23","author":"Khan","year":"2001","journal-title":"Parasite Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib59","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1017\/S0031182000085838","article-title":"Gastrointestinal mucus, a medium for survival and for elimination of parasitic nematodes and protozoa","volume":"94","author":"Miller","year":"1987","journal-title":"Parasitology"},{"key":"10.2353\/ajpath.2007.061245_bib60","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/(SICI)1521-4141(199809)28:09<2672::AID-IMMU2672>3.0.CO;2-F","article-title":"IL-4-regulated enteropathy in an intestinal nematode infection","volume":"28","author":"Lawrence","year":"1998","journal-title":"Eur J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib61","doi-asserted-by":"crossref","first-page":"4734","DOI":"10.1038\/sj.onc.1202865","article-title":"Transforming growth factor-\u03b2 regulates Kit ligand expression in rat ovarian surface epithelial cells","volume":"18","author":"Ismail","year":"1999","journal-title":"Oncogene"},{"key":"10.2353\/ajpath.2007.061245_bib62","doi-asserted-by":"crossref","first-page":"4725","DOI":"10.1182\/blood-2002-08-2521","article-title":"Genetic evidence for convergence of c-Kit- and alpha(4) integrin-mediated signals on class IAPI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells","volume":"101","author":"Tan","year":"2003","journal-title":"Blood"},{"key":"10.2353\/ajpath.2007.061245_bib63","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/jcp.1041480306","article-title":"Murine mast-cell colony formation supported by IL-3, IL-4, and recombinant rat stem-cell factor, ligand for c-Kit","volume":"148","author":"Tsuji","year":"1991","journal-title":"J Cell Physiol"},{"key":"10.2353\/ajpath.2007.061245_bib64","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1091\/mbc.3.3.349","article-title":"Differential expression and processing of 2 cell associated forms of the Kit-ligand\u2014Kl-1 and Kl-2","volume":"3","author":"Huang","year":"1992","journal-title":"Mol Biol Cell"},{"key":"10.2353\/ajpath.2007.061245_bib65","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1046\/j.1365-2249.1999.00824.x","article-title":"Inhibitory effects of transforming growth factor-\u03b2 (TGF-\u03b2) on certain functions of intraepithelial lymphocytes","volume":"115","author":"Ebert","year":"1999","journal-title":"Clin Exp Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib66","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1172\/JCI0214685","article-title":"IL-7 inhibits fibroblast TGF-\u03b2 production and signaling in pulmonary fibrosis","volume":"109","author":"Huang","year":"2002","journal-title":"J Clin Invest"},{"key":"10.2353\/ajpath.2007.061245_bib67","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1182\/blood.V87.8.3375.bloodjournal8783375","article-title":"Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells","volume":"87","author":"Tsujimoto","year":"1996","journal-title":"Blood"},{"key":"10.2353\/ajpath.2007.061245_bib68","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.4049\/jimmunol.151.12.6670","article-title":"Down-regulation of macrophage transforming growth-factor-\u03b2 messenger RNA expression by IL-7","volume":"151","author":"Dubinett","year":"1993","journal-title":"J Immunol"},{"key":"10.2353\/ajpath.2007.061245_bib69","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1172\/JCI200420001","article-title":"Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury","volume":"113","author":"Sun","year":"2004","journal-title":"J Clin Invest"},{"key":"10.2353\/ajpath.2007.061245_bib70","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1006\/cyto.1998.0426","article-title":"Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR","volume":"11","author":"Overbergh","year":"1999","journal-title":"Cytokine"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010623875?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010623875?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T20:33:58Z","timestamp":1684010038000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944010623875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":70,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0002944010623875"],"URL":"https:\/\/doi.org\/10.2353\/ajpath.2007.061245","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}