{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:06:44Z","timestamp":1791198404251,"version":"4.1.0"},"reference-count":72,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.2353\/ajpath.2007.070102","type":"journal-article","created":{"date-parts":[[2007,6,8]],"date-time":"2007-06-08T01:10:02Z","timestamp":1181265002000},"page":"693-701","source":"Crossref","is-referenced-by-count":77,"title":["Pericyte Rho GTPase Mediates Both Pericyte Contractile Phenotype and Capillary Endothelial Growth State"],"prefix":"10.1016","volume":"171","author":[{"given":"Matthew E.","family":"Kutcher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey Y.","family":"Kolyada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard K.","family":"Surks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira M.","family":"Herman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.2353\/ajpath.2007.070102_bib1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nm0603-685","article-title":"Molecular regulation of vessel maturation","volume":"9","author":"Jain","year":"2003","journal-title":"Nat Med"},{"key":"10.2353\/ajpath.2007.070102_bib2","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0008-6363(96)00063-6","article-title":"Pericytes in the microvasculature","volume":"32","author":"Hirschi","year":"1996","journal-title":"Cardiovasc Res"},{"key":"10.2353\/ajpath.2007.070102_bib3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000025622","article-title":"Developmental biology of the vascular smooth muscle cell: building a multilayered vessel wall","volume":"36","author":"Hungerford","year":"1999","journal-title":"J Vasc Res"},{"key":"10.2353\/ajpath.2007.070102_bib4","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0070-2153(01)52010-4","article-title":"Cell-cell interactions in vascular development","volume":"52","author":"Darland","year":"2001","journal-title":"Curr Top Dev Biol"},{"key":"10.2353\/ajpath.2007.070102_bib5","doi-asserted-by":"crossref","first-page":"C947","DOI":"10.1152\/ajpcell.00389.2001","article-title":"Mechanisms of normal and tumor-derived angiogenesis","volume":"282","author":"Papetti","year":"2002","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib6","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nrn2007","article-title":"Macular degeneration: recent advances and therapeutic opportunities","volume":"7","author":"Rattner","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"10.2353\/ajpath.2007.070102_bib7","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.2337\/diacare.27.10.2540","article-title":"Diabetic retinopathy","volume":"27","author":"Fong","year":"2004","journal-title":"Diabetes Care"},{"key":"10.2353\/ajpath.2007.070102_bib8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/jemt.10249","article-title":"Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix","volume":"60","author":"Li","year":"2003","journal-title":"Microsc Res Tech"},{"key":"10.2353\/ajpath.2007.070102_bib9","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1161\/01.RES.0000182903.16652.d7","article-title":"Endothelial\/pericyte interactions","volume":"97","author":"Armulik","year":"2005","journal-title":"Circ Res"},{"key":"10.2353\/ajpath.2007.070102_bib10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0361-9230(99)00260-9","article-title":"Cellular mechanisms of CNS pericytes","volume":"51","author":"Rucker","year":"2000","journal-title":"Brain Res Bull"},{"key":"10.2353\/ajpath.2007.070102_bib11","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1215\/S1152851705000232","article-title":"The role of pericytes in blood-vessel formation and maintenance","volume":"7","author":"Bergers","year":"2005","journal-title":"Neuro-oncol"},{"key":"10.2353\/ajpath.2007.070102_bib12","first-page":"115","article-title":"Role of pericytes in vascular morphogenesis","volume":"94","author":"Betsholtz","year":"2005","journal-title":"EXS"},{"key":"10.2353\/ajpath.2007.070102_bib13","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1083\/jcb.105.3.1455","article-title":"Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells","volume":"105","author":"Orlidge","year":"1987","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib14","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1083\/jcb.109.1.309","article-title":"Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-\u03b21-like molecule by plasmin during co-culture","volume":"109","author":"Sato","year":"1989","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib15","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.yexcr.2005.10.019","article-title":"Pericytes and vascular stability","volume":"312","author":"von Tell","year":"2006","journal-title":"Exp Cell Res"},{"key":"10.2353\/ajpath.2007.070102_bib16","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1242\/dev.125.9.1591","article-title":"A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF","volume":"125","author":"Benjamin","year":"1998","journal-title":"Development"},{"key":"10.2353\/ajpath.2007.070102_bib17","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1083\/jcb.153.3.543","article-title":"Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis","volume":"153","author":"Hellstr\u00f6m","year":"2001","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib18","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.mvr.2006.03.002","article-title":"Pericytes from human non-small cell lung carcinomas: an attractive target for anti-angiogenic therapy","volume":"71","author":"Bagley","year":"2006","journal-title":"Microvasc Res"},{"key":"10.2353\/ajpath.2007.070102_bib19","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1172\/JCI200317929","article-title":"Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors","volume":"111","author":"Bergers","year":"2003","journal-title":"J Clin Invest"},{"key":"10.2353\/ajpath.2007.070102_bib20","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1200\/JCO.2005.07.093","article-title":"A multitargeted, metronomic, and maximum-tolerated dose \u201cchemo-switch\u201d regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer","volume":"23","author":"Pietras","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.2353\/ajpath.2007.070102_bib21","first-page":"1464","article-title":"Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms","volume":"61","author":"Shaheen","year":"2001","journal-title":"Cancer Res"},{"key":"10.2353\/ajpath.2007.070102_bib22","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1042\/BST0330891","article-title":"Rho GTPases and the control of cell behaviour","volume":"33","author":"Hall","year":"2005","journal-title":"Biochem Soc Trans"},{"key":"10.2353\/ajpath.2007.070102_bib23","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1161\/01.HYP.0000148303.98066.ab","article-title":"Hypertension and RhoA\/Rho-kinase signaling in the vasculature: highlights from the recent literature","volume":"44","author":"Lee","year":"2004","journal-title":"Hypertension"},{"key":"10.2353\/ajpath.2007.070102_bib24","first-page":"249","article-title":"Rho proteins and vascular diseases","volume":"98","author":"Pacaud","year":"2005","journal-title":"Arch Mal Coeur Vaiss"},{"key":"10.2353\/ajpath.2007.070102_bib25","doi-asserted-by":"crossref","first-page":"C1116","DOI":"10.1152\/ajpcell.00177.2003","article-title":"Rho GTPase signaling modulates cell shape and contractile phenotype in an isoactin-specific manner","volume":"285","author":"Kolyada","year":"2003","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib26","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1126\/science.6987736","article-title":"Silicone rubber substrata: a new wrinkle in the study of cell locomotion","volume":"208","author":"Harris","year":"1980","journal-title":"Science"},{"key":"10.2353\/ajpath.2007.070102_bib27","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1083\/jcb.101.1.43","article-title":"Microvascular pericytes contain muscle and nonmuscle actins","volume":"101","author":"Herman","year":"1985","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0076-6879(00)25449-9","article-title":"Use and properties of ROCK-specific inhibitor Y-27632","volume":"325","author":"Narumiya","year":"2000","journal-title":"Methods Enzymol"},{"key":"10.2353\/ajpath.2007.070102_bib29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/jemt.1060070104","article-title":"A glow discharge unit to render electron microscope grids and other surfaces hydrophilic","volume":"7","author":"Aebi","year":"1987","journal-title":"J Electron Microsc Tech"},{"key":"10.2353\/ajpath.2007.070102_bib30","doi-asserted-by":"crossref","first-page":"5547","DOI":"10.1073\/pnas.89.12.5547","article-title":"Tight control of gene expression in mammalian cells by tetracycline-responsive promoters","volume":"89","author":"Gossen","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2007.070102_bib31","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1091\/mbc.10.5.1665","article-title":"Ras family GTPases control growth of astrocyte processes","volume":"10","author":"Kalman","year":"1999","journal-title":"Mol Biol Cell"},{"key":"10.2353\/ajpath.2007.070102_bib32","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/40187","article-title":"Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension","volume":"389","author":"Uehata","year":"1997","journal-title":"Nature"},{"key":"10.2353\/ajpath.2007.070102_bib33","doi-asserted-by":"crossref","first-page":"4994","DOI":"10.1167\/iovs.03-0291","article-title":"FGF-2 antagonizes the TGF-\u03b21-mediated induction of pericyte \u03b1-smooth muscle actin expression: a role for myf-5 and Smad-mediated signaling pathways","volume":"44","author":"Papetti","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.2353\/ajpath.2007.070102_bib34","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0026-2862(03)00055-4","article-title":"TGF-\u03b21 signaling controls retinal pericyte contractile protein expression","volume":"66","author":"Sieczkiewicz","year":"2003","journal-title":"Microvasc Res"},{"key":"10.2353\/ajpath.2007.070102_bib35","doi-asserted-by":"crossref","first-page":"15859","DOI":"10.1073\/pnas.2136855100","article-title":"Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: mechanism of pericyte-induced vascular survival in vivo","volume":"100","author":"Shih","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2007.070102_bib36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1023\/A:1016611824696","article-title":"TGF \u03b2 is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1\/2 and endothelial cells","volume":"4","author":"Darland","year":"2001","journal-title":"Angiogenesis"},{"key":"10.2353\/ajpath.2007.070102_bib37","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1083\/jcb.111.2.757","article-title":"Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system","volume":"111","author":"Sato","year":"1990","journal-title":"J Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib38","doi-asserted-by":"crossref","first-page":"7218","DOI":"10.1128\/MCB.21.21.7218-7230.2001","article-title":"Transforming growth factor \u03b21 (TGF-\u03b21) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-\u03b1 signaling","volume":"21","author":"Vi\u00f1als","year":"2001","journal-title":"Mol Cell Biol"},{"key":"10.2353\/ajpath.2007.070102_bib39","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/jcp.20237","article-title":"PKC\/MAPK signaling suppression by retinal pericyte conditioned medium prevents retinal endothelial cell proliferation","volume":"203","author":"Kondo","year":"2005","journal-title":"J Cell Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib40","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/S0002-9440(10)64920-6","article-title":"Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors","volume":"160","author":"Morikawa","year":"2002","journal-title":"Am J Pathol"},{"issue":"Suppl 1","key":"10.2353\/ajpath.2007.070102_bib41","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-2005-861361","article-title":"Pericytes and the pathogenesis of diabetic retinopathy","volume":"37","author":"Hammes","year":"2005","journal-title":"Horm Metab Res"},{"key":"10.2353\/ajpath.2007.070102_bib42","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0002-9440(10)63809-6","article-title":"Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy","volume":"162","author":"Gee","year":"2003","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2007.070102_bib43","doi-asserted-by":"crossref","first-page":"8719","DOI":"10.1016\/S0021-9258(19)50337-4","article-title":"Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction","volume":"267","author":"Hirata","year":"1992","journal-title":"J Biol Chem"},{"key":"10.2353\/ajpath.2007.070102_bib44","doi-asserted-by":"crossref","first-page":"C661","DOI":"10.1152\/ajpcell.00459.2005","article-title":"Physiological role of ROCKs in the cardiovascular system","volume":"290","author":"Noma","year":"2006","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib45","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1152\/physrev.00023.2003","article-title":"Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase","volume":"83","author":"Somlyo","year":"2003","journal-title":"Physiol Rev"},{"key":"10.2353\/ajpath.2007.070102_bib46","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/1097-4652(200009)184:3<409::AID-JCP16>3.0.CO;2-K","article-title":"Molecular mechanism of cGMP-mediated smooth muscle relaxation","volume":"184","author":"Carvajal","year":"2000","journal-title":"J Cell Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib47","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1161\/hy02t2.102960","article-title":"Nitric oxide induces dilation of rat aorta via inhibition of rho-kinase signaling","volume":"39","author":"Chitaley","year":"2002","journal-title":"Hypertension"},{"key":"10.2353\/ajpath.2007.070102_bib48","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1161\/CIRCULATIONAHA.104.510248","article-title":"Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure","volume":"111","author":"Kishi","year":"2005","journal-title":"Circulation"},{"key":"10.2353\/ajpath.2007.070102_bib49","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1161\/01.RES.0000251668.39526.c7","article-title":"Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease","volume":"99","author":"Nohria","year":"2006","journal-title":"Circ Res"},{"key":"10.2353\/ajpath.2007.070102_bib50","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1161\/01.HYP.0000067062.92836.9E","article-title":"Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans","volume":"41","author":"Noma","year":"2003","journal-title":"Hypertension"},{"key":"10.2353\/ajpath.2007.070102_bib51","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1152\/physrev.1998.78.1.53","article-title":"Regulation of the cerebral circulation: role of endothelium and potassium channels","volume":"78","author":"Faraci","year":"1998","journal-title":"Physiol Rev"},{"key":"10.2353\/ajpath.2007.070102_bib52","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1097\/00004647-200112000-00001","article-title":"Relationship of spikes, synaptic activity, and local changes of cerebral blood flow","volume":"21","author":"Lauritzen","year":"2001","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.2353\/ajpath.2007.070102_bib53","doi-asserted-by":"crossref","first-page":"5903","DOI":"10.1073\/pnas.91.13.5903","article-title":"Importance of nitric oxide for local increases of blood flow in rat cerebellar cortex during electrical stimulation","volume":"91","author":"Akg\u00f6ren","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2007.070102_bib54","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0168-0102(02)00122-0","article-title":"Neuronal nitric oxide has a role as a perfusion regulator and a synaptic modulator in cerebellum but not in neocortex during somatosensory stimulation\u2014an animal PET study","volume":"44","author":"Hayashi","year":"2002","journal-title":"Neurosci Res"},{"key":"10.2353\/ajpath.2007.070102_bib55","first-page":"R1153","article-title":"Nitric oxide contributes to functional hyperemia in cerebellar cortex","volume":"268","author":"Iadecola","year":"1995","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib56","first-page":"R1760","article-title":"Nitric oxide is the predominant mediator of cerebellar hyperemia during somatosensory activation in rats","volume":"277","author":"Yang","year":"1999","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-328X(03)00121-9","article-title":"Distribution of Rho family GTPases in the adult rat hippocampus and cerebellum","volume":"114","author":"O'Kane","year":"2003","journal-title":"Brain Res Mol Brain Res"},{"key":"10.2353\/ajpath.2007.070102_bib58","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1161\/01.RES.0000079941.59846.D4","article-title":"Rho\/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension","volume":"92","author":"Ito","year":"2003","journal-title":"Circ Res"},{"key":"10.2353\/ajpath.2007.070102_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0040-8166(88)90002-X","article-title":"In situ analysis of microvascular pericytes in hypertensive rat brains","volume":"20","author":"Herman","year":"1988","journal-title":"Tissue Cell"},{"key":"10.2353\/ajpath.2007.070102_bib60","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0040-8166(87)90005-X","article-title":"Characterization of microvascular cell cultures from normotensive and hypertensive rat brains: pericyte-endothelial cell interactions in vitro","volume":"19","author":"Herman","year":"1987","journal-title":"Tissue Cell"},{"key":"10.2353\/ajpath.2007.070102_bib61","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1291\/hypres.27.263","article-title":"RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats","volume":"27","author":"Moriki","year":"2004","journal-title":"Hypertens Res"},{"key":"10.2353\/ajpath.2007.070102_bib62","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/HJH.0b013e328010b87f","article-title":"Pressor response induced by central angiotensin II is mediated by activation of Rho\/Rho-kinase pathway via AT1 receptors","volume":"25","author":"Sagara","year":"2007","journal-title":"J Hypertens"},{"key":"10.2353\/ajpath.2007.070102_bib63","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ejphar.2004.11.047","article-title":"Inhibition of Rho-kinase stimulates nitric oxide-independent vasorelaxation","volume":"507","author":"L\u00f6hn","year":"2005","journal-title":"Eur J Pharmacol"},{"key":"10.2353\/ajpath.2007.070102_bib64","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1097\/01.hjh.0000251902.85675.7e","article-title":"Angiotensin II\/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase","volume":"24","author":"Savoia","year":"2006","journal-title":"J Hypertens"},{"key":"10.2353\/ajpath.2007.070102_bib65","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1113\/jphysiol.2004.073098","article-title":"Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina","volume":"561","author":"Kawamura","year":"2004","journal-title":"J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib66","first-page":"882","article-title":"Endothelin-induced changes in the physiology of retinal pericytes","volume":"43","author":"Kawamura","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.2353\/ajpath.2007.070102_bib67","first-page":"H2083","article-title":"Cholinergic regulation of pericyte-containing retinal microvessels","volume":"284","author":"Wu","year":"2003","journal-title":"Am J Physiol"},{"key":"10.2353\/ajpath.2007.070102_bib68","first-page":"991","article-title":"Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway","volume":"35","author":"Haefliger","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.2353\/ajpath.2007.070102_bib69","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1006\/mvre.2001.2343","article-title":"Nitric oxide\/cGMP-induced inhibition of calcium and chloride currents in retinal pericytes","volume":"62","author":"Sakagami","year":"2001","journal-title":"Microvasc Res"},{"key":"10.2353\/ajpath.2007.070102_bib70","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1096\/fasebj.7.11.8370472","article-title":"Pericyte physiology","volume":"7","author":"Shepro","year":"1993","journal-title":"FASEB J"},{"key":"10.2353\/ajpath.2007.070102_bib71","first-page":"693","article-title":"Precapillary patterns and perivascular cells in the retinal microvasculature. A scanning electron microscope study","volume":"188","author":"Pannarale","year":"1996","journal-title":"J Anat"},{"key":"10.2353\/ajpath.2007.070102_bib72","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nature05193","article-title":"Bidirectional control of CNS capillary diameter by pericytes","volume":"443","author":"Peppiatt","year":"2006","journal-title":"Nature"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010620019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010620019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T19:14:34Z","timestamp":1628968474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944010620019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0002944010620019"],"URL":"https:\/\/doi.org\/10.2353\/ajpath.2007.070102","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}