{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T11:43:54Z","timestamp":1782387834542,"version":"3.54.5"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["RBIN04CHXT"],"award-info":[{"award-number":["RBIN04CHXT"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002803","name":"Fondazione Cariplo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002803","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["AR041336"],"award-info":[{"award-number":["AR041336"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajp.amjpathol.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.2353\/ajpath.2009.080688","type":"journal-article","created":{"date-parts":[[2009,2,14]],"date-time":"2009-02-14T07:08:28Z","timestamp":1234595308000},"page":"727-735","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Fetal Liver Cells Transplanted in Utero Rescue the Osteopetrotic Phenotype in the oc\/oc Mouse"],"prefix":"10.1016","volume":"174","author":[{"given":"Barbara","family":"Tondelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry C.","family":"Blair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Guerrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth D.","family":"Patrene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Cassani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Vezzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Lucchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.2353\/ajpath.2009.080688_bib1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/77131","article-title":"Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis","volume":"25","author":"Frattini","year":"2000","journal-title":"Nat Genet"},{"key":"10.2353\/ajpath.2009.080688_bib2","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0022-3476(05)82004-9","article-title":"Bone marrow transplantation for autosomal recessive osteopetrosis. A report from the Working Party on Inborn Errors of the European Bone Marrow Transplantation Group","volume":"125","author":"Gerritsen","year":"1994","journal-title":"J Pediatr"},{"key":"10.2353\/ajpath.2009.080688_bib3","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/sj.bmt.1704194","article-title":"Long-term outcome of haematopoietic stem cell transplantation in autosomal recessive osteopetrosis: an EBMT report","volume":"32","author":"Driessen","year":"2003","journal-title":"Bone Marrow Transplant"},{"key":"10.2353\/ajpath.2009.080688_bib4","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1182\/blood.V94.7.2179.419k43_2179_2191","article-title":"In utero hematopoietic stem cell transplantation: ontogenic opportunities and biologic barriers","volume":"94","author":"Flake","year":"1999","journal-title":"Blood"},{"key":"10.2353\/ajpath.2009.080688_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S8756-3282(99)00278-1","article-title":"The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc\/oc) mutants","volume":"26","author":"Scimeca","year":"2000","journal-title":"Bone"},{"key":"10.2353\/ajpath.2009.080688_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0002-9440(10)63798-4","article-title":"Genotype-phenotype relationship in human ATP6i-dependent autosomal recessive osteopetrosis","volume":"162","author":"Taranta","year":"2003","journal-title":"Am J Pathol"},{"key":"10.2353\/ajpath.2009.080688_bib7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/humu.20076","article-title":"TCIRG1-dependent recessive osteopetrosis: mutation analysis, functional identification of the splicing defects, and in vitro rescue by U1 snRNA","volume":"24","author":"Susani","year":"2004","journal-title":"Hum Mutat"},{"key":"10.2353\/ajpath.2009.080688_bib8","doi-asserted-by":"crossref","first-page":"14629","DOI":"10.1073\/pnas.0507637102","article-title":"Rescue of ATPa3-deficient murine malignant osteopetrosis by hematopoietic stem cell transplantation in utero","volume":"102","author":"Frattini","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2009.080688_bib9","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1182\/blood.V99.5.1870","article-title":"Allogenic fetal liver cells have a distinct competitive engraftment advantage over adult bone marrow cells when infused into fetal as compared with adult severe combined immunodeficient recipients","volume":"99","author":"Taylor","year":"2002","journal-title":"Blood"},{"key":"10.2353\/ajpath.2009.080688_bib10","first-page":"293","article-title":"Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term","volume":"25","author":"Harrison","year":"1997","journal-title":"Exp Hematol"},{"key":"10.2353\/ajpath.2009.080688_bib11","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.1182\/blood-2006-12-061382","article-title":"Hematopoietic stem cell-targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc\/oc mice","volume":"109","author":"Johansson","year":"2007","journal-title":"Blood"},{"key":"10.2353\/ajpath.2009.080688_bib12","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1093\/oxfordjournals.humrep.a137554","article-title":"In utero transplantation of fetal liver stem cells into human fetuses","volume":"7","author":"Touraine","year":"1992","journal-title":"Hum Reprod"},{"key":"10.2353\/ajpath.2009.080688_bib13","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.bbmt.2008.02.012","article-title":"In utero hematopoietic stem cell transplantation: progress toward clinical application","volume":"14","author":"Merianos","year":"2008","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.2353\/ajpath.2009.080688_bib14","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0014-5793(97)00313-X","article-title":"\u2018Green mice\u2019 as a source of ubiquitous green cells","volume":"407","author":"Okabe","year":"1997","journal-title":"FEBS Lett"},{"key":"10.2353\/ajpath.2009.080688_bib15","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1046\/j.1538-7836.2003.00030.x","article-title":"In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses","volume":"1","author":"Rosen","year":"2003","journal-title":"J Thromb Haemost"},{"key":"10.2353\/ajpath.2009.080688_bib16","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0168-9525(00)89107-6","article-title":"Mouse embryonic hematopoiesis","volume":"11","author":"Dzierzak","year":"1995","journal-title":"Trends Genet"},{"key":"10.2353\/ajpath.2009.080688_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/154732804773099218","article-title":"Commentary: the role of cell migration in the ontogeny of the lymphoid system","volume":"13","author":"Moore","year":"2004","journal-title":"Stem Cells Dev"},{"key":"10.2353\/ajpath.2009.080688_bib18","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.exphem.2005.11.010","article-title":"Neonatal hematopoietic stem cell transplantation cures oc\/oc mice from osteopetrosis","volume":"34","author":"Johansson","year":"2006","journal-title":"Exp Hematol"},{"key":"10.2353\/ajpath.2009.080688_bib19","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S0140-6736(96)09392-0","article-title":"In-utero transplantation of parental CD34 haematopoietic progenitor cells in a patient with X-linked severe combined immunodeficiency (SCIDXI)","volume":"348","author":"Wengler","year":"1996","journal-title":"Lancet"},{"key":"10.2353\/ajpath.2009.080688_bib20","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1172\/JCI28310","article-title":"Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect","volume":"116","author":"Bowie","year":"2006","journal-title":"J Clin Invest"},{"key":"10.2353\/ajpath.2009.080688_bib21","doi-asserted-by":"crossref","first-page":"5878","DOI":"10.1073\/pnas.0700460104","article-title":"Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties","volume":"104","author":"Bowie","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.2353\/ajpath.2009.080688_bib22","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cell.2007.06.011","article-title":"Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells","volume":"130","author":"Kim","year":"2007","journal-title":"Cell"},{"key":"10.2353\/ajpath.2009.080688_bib23","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0192-0561(00)00076-X","article-title":"Perinatal fetal-cell and gene therapy","volume":"22","author":"Touraine","year":"2000","journal-title":"Int J Immunopharmacol"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010609340?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944010609340?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:49:30Z","timestamp":1762080570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944010609340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0002944010609340"],"URL":"https:\/\/doi.org\/10.2353\/ajpath.2009.080688","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fetal Liver Cells Transplanted in Utero Rescue the Osteopetrotic Phenotype in the oc\/oc Mouse","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.2353\/ajpath.2009.080688","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}