{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T01:27:47Z","timestamp":1772242067947,"version":"3.50.1"},"reference-count":96,"publisher":"Edizioni Minerva Medica","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Minerva Gastroenterol Dietol"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.23736\/s1121-421x.19.02577-7","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T09:03:00Z","timestamp":1579078980000},"source":"Crossref","is-referenced-by-count":23,"title":["The gut and the inflammatory bowel diseases inside-out: extra-intestinal manifestations"],"prefix":"10.23736","volume":"65","author":[{"given":"Davide G.","family":"Ribaldone","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinaldo","family":"Pellicano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni C.","family":"Actis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17149","reference":[{"key":"10.23736\/S1121-421X.19.02577-7_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2014.02.019"},{"key":"10.23736\/S1121-421X.19.02577-7_ref002","doi-asserted-by":"publisher","DOI":"10.3390\/gidisord1010010"},{"key":"10.23736\/S1121-421X.19.02577-7_ref003","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4806.17.05050-9"},{"key":"10.23736\/S1121-421X.19.02577-7_ref004","doi-asserted-by":"publisher","DOI":"10.2174\/1574887113666180910120959"},{"key":"10.23736\/S1121-421X.19.02577-7_ref005","doi-asserted-by":"publisher","DOI":"10.23736\/S1121-421X.17.02402-3"},{"key":"10.23736\/S1121-421X.19.02577-7_ref006","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-017-1666-0"},{"key":"10.23736\/S1121-421X.19.02577-7_ref007","doi-asserted-by":"publisher","DOI":"10.1586\/egh.11.23"},{"key":"10.23736\/S1121-421X.19.02577-7_ref008","first-page":"401","article-title":"The pathologic galaxy modulating the genotype and phenotype of inflammatory bowel disease: comorbidity, contiguity, and genetic and epigenetic factors","volume":"107","author":"Actis GC","year":"2016","journal-title":"Minerva Med"},{"key":"10.23736\/S1121-421X.19.02577-7_ref009","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2017.4845\/2017"},{"key":"10.23736\/S1121-421X.19.02577-7_ref010","first-page":"233","article-title":"Pathogenesis and clinical approach to extraintestinal manifestations of inflammatory bowel disease","volume":"53","author":"Agrawal D","year":"2007","journal-title":"Minerva Gastroenterol Dietol"},{"key":"10.23736\/S1121-421X.19.02577-7_ref011","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026629528233"},{"key":"10.23736\/S1121-421X.19.02577-7_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)90839-S"},{"key":"10.23736\/S1121-421X.19.02577-7_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(94)90066-3"},{"key":"10.23736\/S1121-421X.19.02577-7_ref014","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12723"},{"key":"10.23736\/S1121-421X.19.02577-7_ref015","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197609000-00004"},{"key":"10.23736\/S1121-421X.19.02577-7_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2009.11.005"},{"key":"10.23736\/S1121-421X.19.02577-7_ref017","doi-asserted-by":"publisher","DOI":"10.2174\/187152809788681001"},{"key":"10.23736\/S1121-421X.19.02577-7_ref018","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-018-1668-z"},{"key":"10.23736\/S1121-421X.19.02577-7_ref019","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20061775"},{"key":"10.23736\/S1121-421X.19.02577-7_ref020","doi-asserted-by":"publisher","DOI":"10.1038\/nature02119"},{"key":"10.23736\/S1121-421X.19.02577-7_ref021","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.1.557-565.2006"},{"key":"10.23736\/S1121-421X.19.02577-7_ref022","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X16644242"},{"key":"10.23736\/S1121-421X.19.02577-7_ref023","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000067"},{"key":"10.23736\/S1121-421X.19.02577-7_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6918(11)70006-3"},{"key":"10.23736\/S1121-421X.19.02577-7_ref025","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.5517"},{"key":"10.23736\/S1121-421X.19.02577-7_ref026","doi-asserted-by":"publisher","DOI":"10.1038\/35079107"},{"key":"10.23736\/S1121-421X.19.02577-7_ref027","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135245"},{"key":"10.23736\/S1121-421X.19.02577-7_ref028","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-011-0198-2"},{"key":"10.23736\/S1121-421X.19.02577-7_ref029","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-019-00797-3"},{"key":"10.23736\/S1121-421X.19.02577-7_ref030","first-page":"270","article-title":"Co-morbid immunopathological affections in outpatients with inflammatory bowel disease: a prospective study","volume":"62","author":"Actis GC","year":"2016","journal-title":"Minerva Gastroenterol Dietol"},{"key":"10.23736\/S1121-421X.19.02577-7_ref031","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv178"},{"key":"10.23736\/S1121-421X.19.02577-7_ref032","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150630"},{"key":"10.23736\/S1121-421X.19.02577-7_ref033","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4806.17.05118-7"},{"key":"10.23736\/S1121-421X.19.02577-7_ref034","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.163"},{"key":"10.23736\/S1121-421X.19.02577-7_ref035","doi-asserted-by":"publisher","DOI":"10.1136\/gut.38.3.384"},{"key":"10.23736\/S1121-421X.19.02577-7_ref036","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24307"},{"key":"10.23736\/S1121-421X.19.02577-7_ref037","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2004.09.003"},{"key":"10.23736\/S1121-421X.19.02577-7_ref038","doi-asserted-by":"publisher","DOI":"10.23736\/S0031-0808.17.03359-6"},{"key":"10.23736\/S1121-421X.19.02577-7_ref039","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2015.1064995"},{"key":"10.23736\/S1121-421X.19.02577-7_ref040","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-017-2829-1"},{"key":"10.23736\/S1121-421X.19.02577-7_ref041","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.343"},{"key":"10.23736\/S1121-421X.19.02577-7_ref042","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(02)00014-1"},{"key":"10.23736\/S1121-421X.19.02577-7_ref043","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)91209-O"},{"key":"10.23736\/S1121-421X.19.02577-7_ref044","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.35396"},{"key":"10.23736\/S1121-421X.19.02577-7_ref045","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2012.02.020"},{"key":"10.23736\/S1121-421X.19.02577-7_ref046","doi-asserted-by":"publisher","DOI":"10.1038\/s41395-018-0422-z"},{"key":"10.23736\/S1121-421X.19.02577-7_ref047","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i20.4802"},{"key":"10.23736\/S1121-421X.19.02577-7_ref048","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(48)90611-4"},{"key":"10.23736\/S1121-421X.19.02577-7_ref049","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh722"},{"key":"10.23736\/S1121-421X.19.02577-7_ref050","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2014.4410"},{"key":"10.23736\/S1121-421X.19.02577-7_ref051","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S108855"},{"key":"10.23736\/S1121-421X.19.02577-7_ref052","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-016-0645-8"},{"key":"10.23736\/S1121-421X.19.02577-7_ref053","first-page":"136","article-title":"Crohn's disease and acute pancreatitis. A review of literature","volume":"16","author":"Jasdanwala S","year":"2015","journal-title":"JOP"},{"key":"10.23736\/S1121-421X.19.02577-7_ref054","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.1420"},{"key":"10.23736\/S1121-421X.19.02577-7_ref055","first-page":"84","article-title":"Inflammatory bowel diseases and primary sclerosing cholangitis: hepatic and pancreatic side effects due to azathioprine","volume":"17","author":"Pallavicino F","year":"2013","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.23736\/S1121-421X.19.02577-7_ref056","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e3181bd6501"},{"key":"10.23736\/S1121-421X.19.02577-7_ref057","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1945.00890140064007"},{"key":"10.23736\/S1121-421X.19.02577-7_ref058","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv128"},{"key":"10.23736\/S1121-421X.19.02577-7_ref059","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2008.72"},{"key":"10.23736\/S1121-421X.19.02577-7_ref060","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000614"},{"key":"10.23736\/S1121-421X.19.02577-7_ref061","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4946.18.04997-6"},{"key":"10.23736\/S1121-421X.19.02577-7_ref062","doi-asserted-by":"publisher","DOI":"10.4161\/cc.6.6.3990"},{"key":"10.23736\/S1121-421X.19.02577-7_ref063","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2014.00197"},{"key":"10.23736\/S1121-421X.19.02577-7_ref064","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-015-0141-9"},{"key":"10.23736\/S1121-421X.19.02577-7_ref065","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e3182088158"},{"key":"10.23736\/S1121-421X.19.02577-7_ref066","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-015-0522-5"},{"key":"10.23736\/S1121-421X.19.02577-7_ref067","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2442-0"},{"key":"10.23736\/S1121-421X.19.02577-7_ref068","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000650"},{"key":"10.23736\/S1121-421X.19.02577-7_ref069","doi-asserted-by":"publisher","DOI":"10.1126\/science.8197455"},{"key":"10.23736\/S1121-421X.19.02577-7_ref070","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7310029"},{"key":"10.23736\/S1121-421X.19.02577-7_ref071","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907206"},{"key":"10.23736\/S1121-421X.19.02577-7_ref072","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-019-00333-w"},{"key":"10.23736\/S1121-421X.19.02577-7_ref073","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20092366"},{"key":"10.23736\/S1121-421X.19.02577-7_ref074","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1100721"},{"key":"10.23736\/S1121-421X.19.02577-7_ref075","doi-asserted-by":"publisher","DOI":"10.23736\/S1120-4826.17.02276-5"},{"key":"10.23736\/S1121-421X.19.02577-7_ref076","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v4.i3.41"},{"key":"10.23736\/S1121-421X.19.02577-7_ref077","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.06.057"},{"key":"10.23736\/S1121-421X.19.02577-7_ref078","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-005-0115-8"},{"key":"10.23736\/S1121-421X.19.02577-7_ref079","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00769.x"},{"key":"10.23736\/S1121-421X.19.02577-7_ref080","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4946.18.05425-7"},{"key":"10.23736\/S1121-421X.19.02577-7_ref081","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12572"},{"key":"10.23736\/S1121-421X.19.02577-7_ref082","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61382-9"},{"key":"10.23736\/S1121-421X.19.02577-7_ref083","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i30.4819"},{"key":"10.23736\/S1121-421X.19.02577-7_ref084","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-008-9080-z"},{"key":"10.23736\/S1121-421X.19.02577-7_ref085","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-10-132"},{"key":"10.23736\/S1121-421X.19.02577-7_ref086","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2011.02069.x"},{"key":"10.23736\/S1121-421X.19.02577-7_ref087","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx180.529"},{"key":"10.23736\/S1121-421X.19.02577-7_ref088","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3444"},{"key":"10.23736\/S1121-421X.19.02577-7_ref089","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100191"},{"key":"10.23736\/S1121-421X.19.02577-7_ref090","doi-asserted-by":"publisher","DOI":"10.1038\/nm1718"},{"key":"10.23736\/S1121-421X.19.02577-7_ref091","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.11.030"},{"key":"10.23736\/S1121-421X.19.02577-7_ref092","doi-asserted-by":"publisher","DOI":"10.23736\/S1121-421X.17.02386-8"},{"key":"10.23736\/S1121-421X.19.02577-7_ref093","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1019378108"},{"key":"10.23736\/S1121-421X.19.02577-7_ref094","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20051745"},{"key":"10.23736\/S1121-421X.19.02577-7_ref095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03797.x"},{"key":"10.23736\/S1121-421X.19.02577-7_ref096","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4806.17.05444-1"}],"container-title":["Minerva Gastroenterologica e Dietologica"],"original-title":[],"link":[{"URL":"https:\/\/www.minervamedica.it\/pdf.php?cod=R08Y2019N04A0309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T09:04:44Z","timestamp":1579079084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.minervamedica.it\/index2.php?show=R08Y2019N04A0309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":96,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.23736\/s1121-421x.19.02577-7","relation":{"is-cited-by":[{"id-type":"doi","id":"10.23736\/S1121-421X.19.02611-4","asserted-by":"object"}]},"ISSN":["1121-421X","1827-1642"],"issn-type":[{"value":"1121-421X","type":"print"},{"value":"1827-1642","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}