{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:42:03Z","timestamp":1776868923926,"version":"3.51.2"},"reference-count":14,"publisher":"Mattioli1885","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,22]]},"abstract":"<jats:p>Although less commonly used than internal dose indicators, biological effect indicators can be valuable for Risk Assessment. Among the\u00a0numerous\u00a0biomarkers used to date, those\u00a0that\u00a0indicate\u00a0DNA damage could be especially useful for occupational safety, as they predict the\u00a0risk\u00a0of\u00a0carcinogenesis. The most common among these assays is the micronucleus test. Unfortunately, this test cannot be performed on human erythrocytes;\u00a0to\u00a0apply\u00a0it\u00a0to\u00a0lymphocytes,\u00a0it requires invasive blood sampling, limiting its use to scientific research. We have developed a new method that enables the micronucleus test to be conducted in a\u00a0rapid,\u00a0non-invasive, and cost-effective\u00a0manner. The test is performed on immature erythrocytes (reticulocytes) in human blood smears collected via a finger prick and stained with Acridine Orange. This new protocol allows the micronucleus test to be applied to human blood samples in a manner compatible with occupational safety procedures.\u00a0<\/jats:p>","DOI":"10.23749\/mdl.2026.17996","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T13:50:44Z","timestamp":1776865844000},"page":"17996","source":"Crossref","is-referenced-by-count":0,"title":["The Micronucleus Test for Occupational Safety"],"prefix":"10.23749","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8218-1711","authenticated-orcid":false,"given":"Ion","family":"Udroiu","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze, Universit\u00e0 degli Studi Roma Tre, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Giliberti","sequence":"first","affiliation":[{"name":"INAIL, Istituto Nazionale per l'Assicurazione contro gli Infortuni sul Lavoro, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Sgura","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze, Universit\u00e0 degli Studi Roma Tre, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27750","reference":[{"key":"10.23749\/mdl.2026.17996_ref1","doi-asserted-by":"crossref","unstructured":"1. 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