{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:48:48Z","timestamp":1790246928381,"version":"4.1.0"},"reference-count":0,"publisher":"Mattioli1885","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,24]]},"abstract":"<jats:p>Objective: We carried out a systematic review and meta-analysis of epidemiologic studies on the association between occupational exposure to glyphosate and risk of non-Hodgkin lymphoma (NHL) and multiple myeloma (MM). Methods: We conducted a systematic search of the literature, and identified 18 relevant publications, from which we extracted results from seven non-overlapping studies of NHL and three of MM. We performed random-effects meta-analyses for ever-exposure to glyphosate, dose-response, and risk of specific NHL subtypes. Results: The meta-relative risk (RR) of NHL was 1.03 (95% confidence interval [CI] 0.86-1.21), that of MM was 1.04 (95% CI 0.67-1.41). The meta-RR of NHL for highest category of exposure was 1.49 (95% CI 0.37-2.61; 3 studies). The meta-RR for diffuse large B-cell lymphoma (DLBCL) was 1.31 (95% CI 0.93-1.75); that for follicular lymphoma was 0.82 (95% CI 0.93-1.70), and that for chronic lymphocytic leukemia was 0.85 (95% CI 0.20-1.49). There was indication of publication bias for studies on NHL. Conclusions: Our meta-analysis provided no overall evidence of an increased risk for both NHL and MM in subjects occupationally exposed to glyphosate. In secondary analyses we detected a small increase in risk for the category with highest level of exposure as well as for DLBCL. The evidence of publication bias suggests caution in the interpretation of the results.<\/jats:p>","DOI":"10.23749\/mdl.v111i1.8967","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T07:58:01Z","timestamp":1741161481000},"page":"63-73","source":"Crossref","is-referenced-by-count":5,"title":["Exposure to glyphosate and risk of non-Hodgkin lymphoma and multiple myeloma: an updated meta-analysis","Esposizione al glifosato e rischio di linfoma non Hodgkin e mieloma multiplo: una meta-analisi aggiornata"],"prefix":"10.23749","volume":"111","author":[{"given":"Francesca","family":"Donato","sequence":"additional","affiliation":[{"name":"department of pediatrics and public health, university of turin, italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Pira","sequence":"additional","affiliation":[{"name":"department of pediatrics and public health, university of turin, italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Ciocan","sequence":"additional","affiliation":[{"name":"department of pediatrics and public health, university of turin, italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27750","container-title":["La Medicina del Lavoro","La Medicina del Lavoro | Work, Environment and Health"],"original-title":[],"link":[{"URL":"https:\/\/mail.mattioli1885journals.com\/index.php\/lamedicinadellavoro\/article\/download\/8967\/8543","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/mail.mattioli1885journals.com\/index.php\/lamedicinadellavoro\/article\/download\/8967\/8544","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/mail.mattioli1885journals.com\/index.php\/lamedicinadellavoro\/article\/download\/8967\/8543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T11:14:59Z","timestamp":1741778099000},"score":1,"resource":{"primary":{"URL":"https:\/\/mail.mattioli1885journals.com\/index.php\/lamedicinadellavoro\/article\/view\/8967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,24]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.23749\/mdl.v111i1.8967","relation":{"has-manifestation":[{"id-type":"other","id":"4-732-8967-g8543","asserted-by":"subject"},{"id-type":"other","id":"4-732-8967-g8544","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"4-732","asserted-by":"subject"}],"is-cited-by":[{"id-type":"doi","id":"10.1080\/10408347.2021.2013157","asserted-by":"object"}]},"ISSN":["2532-1080","0025-7818"],"issn-type":[{"value":"2532-1080","type":"electronic"},{"value":"0025-7818","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,24]]},"article-number":"5"}}