{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:24:38Z","timestamp":1792038278839,"version":"4.4.0"},"reference-count":22,"publisher":"Mattioli1885","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,15]]},"abstract":"<jats:p>Objective: We updated a recent systematic review and meta-analysis of epidemiologic studies to help clarifying the association between exposure to glyphosate and risk of non-Hodgkin lymphoma (NHL). Methods: We conducted an updated search of the literature, and identified a total of 15 relevant publications, from which we extracted results from six non-overlapping studies. We performed random-effects meta-analyses for ever-exposure to glyphosate, dose-response, and risk of specific NHL subtypes Results: The meta-RR for ever-exposure to glyphosate was 1.05 (95% confidence interval [CI] 0.90-1.24; I2 = 0%). The meta-RR for the highest category of exposure was 1.15 (95% CI 0.72-1.83; 3 studies). The meta-RR for diffuse large B-cell lymphoma (DLBCL) was 1.29 (95% CI 1.02-1.63; 4 studies), that for follicular lymphoma was 0.84 (95% CI 0.61-1.17), and that for chronic lymphocytic leukemia\/small lymphocytic lymphoma was 1.33 (95% CI 0.65-2.70). There was indication of publication bias. Conclusions: This updated meta-analysis reinforces our previous conclusion of a lack of an association between exposure to glyphosate and risk of NHL overall, although an association with DLBCL cannot be ruled out.<\/jats:p>","DOI":"10.23749\/mdl.v112i3.11123","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T07:58:01Z","timestamp":1741161481000},"page":"194-199","source":"Crossref","is-referenced-by-count":5,"title":["Exposure to glyphosate and risk of non-Hodgkin lymphoma: an updated meta-analysis"],"prefix":"10.23749","volume":"112","author":[{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[{"name":"Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY, USA; Department of Medical and Surgical Sciences, University of Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Ciocan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Public Health, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlotta","family":"Zunarelli","sequence":"additional","affiliation":[{"name":"University of Bologna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Pira","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Public Health, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27750","reference":[{"key":"10.23749\/mdl.v112i3.11123_ref1","doi-asserted-by":"crossref","unstructured":"- Donato F, Pira E, Ciocan C, Boffetta P. 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