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Methods:The repeated measures study was conducted\u00a0on 40 construction workers exposed to HTV (5 m\/s2 rms with frequencies of 31.5, 63, and 125 Hz), HTV (10\u00a0m\/s2 rms- 31.5 Hz), noise (90 dBA), and concurrent exposure (noise (90 dBA) + HTV (10 m\/s2 rms- 31.5 Hz)) with\u00a0the typical vibrating hand-held tool for 30 minutes. Electromyography signals determined each worker\u2019s fatigue level\u00a0in the Flexor digitorum superficialis (FDS) muscle in two pre- and post-exposure periods. The subjects also filled out\u00a0the visual analog scale to evaluate mental fatigue severity subjectively. Results:The mean difference\u00a0of muscle fatigue\u00a0parameters was significant in all scenarios except for the two scenarios of alone exposure to HTV (5 m\/s2 -125 Hz\u00a0and noise exposure (p-value &lt; 0.05). The mean difference of mental fatigue in all scenarios except for the two scenarios\u00a0of exposure to HTV (5 m\/s2 -125 Hz) and exposure to HTV (5 m\/s2 -63 Hz) was significant (p-value &lt; 0.05). The\u00a0most differences in muscle fatigue parameters (Amplitude = 8.16\u00b15.63, Mean frequency=-4.69\u00b13.78) and mental\u00a0fatigue (4.97\u00b12.38) were observed in the simultaneous exposure to noise and HTV. Conclusion: Noise exposure\u00a0alone cannot produce remarkable effects on muscle fatigue but can aggravate the effects of vibrations as a consequence\u00a0of synergistic interaction. However, the role of noise on perceived mental fatigue was more dominant than the HTV.\u00a0These findings should be considered to adapt the existing exposure limits to actual work conditions.<\/jats:p>","DOI":"10.23749\/mdl.v114i2.13903","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T07:58:01Z","timestamp":1741161481000},"page":"e2023021","source":"Crossref","is-referenced-by-count":4,"title":["Combined Effects of Noise and Hand-transmitted Vibration on Workers\u2019 Muscle and Mental Fatigues in a Simulated Construction Operation"],"prefix":"10.23749","volume":"114","author":[{"given":"Seyed Hojat","family":"Mousavi Kordmiri","sequence":"first","affiliation":[{"name":"Center of Excellence for Occupational Health, School of Public Health and Occupational Health & Safety Research Center, Hamadan University of Medical Sciences, Hamadan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Aliabadi","sequence":"additional","affiliation":[{"name":"Center of Excellence for Occupational Health, School of Public Health and Occupational Health & Safety Research Center, Hamadan University of Medical Sciences, Hamadan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rostam","family":"Golmohammadi","sequence":"additional","affiliation":[{"name":"Center of Excellence for Occupational Health, School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Bovenzi","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine, Department of Medical Sciences, University of Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Farhadian","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27750","reference":[{"key":"10.23749\/mdl.v114i2.13903_ref1","unstructured":"REFERENCES"},{"key":"10.23749\/mdl.v114i2.13903_ref2","doi-asserted-by":"crossref","unstructured":"Lai S-K, Chui J, Tong L, Sun J-Q. 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