{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T19:15:01Z","timestamp":1774984501524,"version":"3.50.1"},"reference-count":40,"publisher":"The Korean Society of Nephrology","issue":"3","license":[{"start":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T00:00:00Z","timestamp":1721779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002543","name":"Pusan National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["krcp-ksn.org"],"crossmark-restriction":true},"short-container-title":["Kidney Res Clin Pract"],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:p>Background: It is unclear whether poor glycemic control contributes to residual kidney function (RKF) decline and consequent volume overload in diabetic patients on peritoneal dialysis (PD). Methods: This retrospective analysis included 80 diabetic patients who started PD at a single center. The first 2 years of patient data were collected to investigate the impact of glycemic control on RKF and volume overload in the early stages of PD. We used the time-averaged glycated hemoglobin (HbA1c) levels to estimate glycemic control. RKF loss was measured as the slope of RKF decline and time to anuria. To assess the association between glycemic control and volume overload, we examined technique failure (TF) associated with volume overload (TFVO), defined as TF due to excessive fluid accumulation. Multivariable linear regression and Cox regression analysis were performed to assess how glycemic control affects RKF and TFVO. Results: Over the first 2 years, the mean rate of RKF decline was \u20133.25 \u00b1 3.94 mL\/min\/ 1.73 m2 per year. Multivariable linear regression showed that higher time-averaged HbA1c was associated with a rapid RKF decline (\u03b2 = \u20130.95; 95% confidence interval [CI], \u20131.66 to \u20130.24; p = 0.01). In the adjusted Cox regression analysis, higher time-averaged HbA1c increased the risk of progression to anuria (adjusted hazard ratio [HR], 1.97; 95% CI, 1.29\u20133.00; p = 0.002) and TFVO (adjusted HR, 2.88; 95% CI, 1.41\u20135.89; p = 0.004). Conclusion: Poor glycemic control is associated with rapid RKF decline and leads to volume overload in diabetic patients on PD.<\/jats:p>","DOI":"10.23876\/j.krcp.23.251","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T09:24:40Z","timestamp":1721813080000},"page":"481-490","update-policy":"https:\/\/doi.org\/10.23876\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of glycemic control on residual kidney function and technique failure associated with volume overload in diabetic patients on peritoneal dialysis"],"prefix":"10.23876","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9962-6625","authenticated-orcid":true,"given":"Dong Eon","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9471-5976","authenticated-orcid":true,"given":"Da Woon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9289-9073","authenticated-orcid":true,"given":"Hyo Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6257-8551","authenticated-orcid":true,"given":"Harin","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6006-0051","authenticated-orcid":true,"given":"Eun Young","family":"Seong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6936-6395","authenticated-orcid":true,"given":"Yewon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8218-6974","authenticated-orcid":true,"given":"Sang Heon","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"9960","reference":[{"key":"ref1","volume-title":"","year":"2022"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.23876\/j.krcp.20.202"},{"key":"ref3","first-page":"619","volume-title":"Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy: a marginal structural model analysis","author":"Lukowsky","year":"2013"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2010.00096"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(03)00362-7"},{"key":"ref6","first-page":"S42","volume-title":"Benefits of preserving residual renal function in peritoneal dialysis","author":"Marr\u00f3n","year":"2008"},{"key":"ref7","first-page":"198","volume-title":"Adequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcomes","year":"1996"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2013.00075"},{"key":"ref9","first-page":"110","volume-title":"Predictors of residual renal function loss in peritoneal dialysis: is previous renal transplantation a risk factor?","author":"Bernardo","year":"2009"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(99)70102-2"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.723720"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1111732"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2009.00208"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2014.00008"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.23876\/j.krcp.20.153"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft296"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.5.1242"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/20543581221150590"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00161-1"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2011.00137"},{"key":"ref21","first-page":"S5","volume-title":"Evaluation and management of ultrafiltration problems in peritoneal dialysis. 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