{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:48:07Z","timestamp":1789433287431,"version":"build-2803163510"},"reference-count":30,"publisher":"The Japan Society of Coloproctology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Anus Rectum Colon"],"published-print":{"date-parts":[[2025,7,25]]},"DOI":"10.23922\/jarc.2024-112","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T22:12:15Z","timestamp":1753395135000},"page":"321-329","source":"Crossref","is-referenced-by-count":3,"title":["Fibrinogen-Albumin Ratio: An Independent Recurrence Factor for Colorectal Cancer Stages II and III in a Competing Risk Model"],"prefix":"10.23922","volume":"9","author":[{"given":"Michiaki","family":"Shimada","sequence":"first","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Goi","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Tagai","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuzi","family":"Sawai","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Morikawa","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Tamaki","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Koneri","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Faculty of Medicine, University of Fukui"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10009","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Matsumoto K, Hatakeyama Y, Seto K, et al. Cost of illness for colorectal cancer in Japan - a time trend and future projections (1996-2035) based on governmental statistics. BMC Health Serv Res. 2023 Aug; 23 (1): 888.","DOI":"10.1186\/s12913-023-09831-8"},{"key":"2","unstructured":"2. Hashiguchi Y, Muro K, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. Int J Clin Oncol. 2020 Jan; 25 (1): 1-42."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Yamamoto T, Kawada K, Obama K. Inflammation-related biomarkers for the prediction of prognosis in colorectal cancer patients. Int J Mol Sci. 2021 Jul; 22 (15): 8002.","DOI":"10.3390\/ijms22158002"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Vilar R, Fish RJ, Casini A, et al. Fibrinogen in human disease: Both friend and foe. Haematologica. 2020 Jan; 105 (2): 284-96.","DOI":"10.3324\/haematol.2019.236901"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Otani K, Ishihara S, Hata K, et al. Colorectal cancer with venous tumor thrombosis. Asian Journal of Surgery. 2018 May; 41 (3): 197-202.","DOI":"10.1016\/j.asjsur.2016.07.013"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Sun ZQ, Han XN, Wang HJ, et al. Prognostic significance of preoperative fibrinogen in patients with colon cancer. World J Gastroenterol. 2014 Jul; 20 (26): 8583-91.","DOI":"10.3748\/wjg.v20.i26.8583"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Li M, Wu Y, Zhang J, et al. Prognostic value of pretreatment plasma fibrinogen in patients with colorectal cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2019 Sep; 98 (37): e16974.","DOI":"10.1097\/MD.0000000000016974"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Zhao X, Zhou Y, Liu B, et al. Preoperative neutrophil-lymphocyte ratio (NLR) binding fibrinogen-albumin ratio (FAR) is superior to platelet-lymphocyte ratio (PLR) -binding fibrinogen-albumin ratio (FAR) and lymphocyte-monocyte (LMR) -binding fibrinogen-albumin ratio (FAR) as predictors of survival in surgical patients with colorectal adenocarcinoma. Med Sci Monit. 2023 Mar; 29: e939442.","DOI":"10.12659\/MSM.939442"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Liao YC, Fu M, Wang XF, et al. Combined fibrinogen-to-pre-albumin ratio and carbohydrate antigen 19-9 score is a promising metric to predict progression of metastatic colorectal mucinous adenocarcinoma. J Clin Lab Anal. 2021 May; 35 (5): e23757.","DOI":"10.1002\/jcla.23757"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Ying HQ, Chen W, Xiong CF, et al. Quantification of fibrinogen-to-pre-albumin ratio provides an integrating parameter for differential diagnosis and risk stratification of early-stage colorectal cancer. Cancer Cell Int. 2022 Mar; 22 (1): 137.","DOI":"10.1186\/s12935-022-02532-y"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Li K, Yan J, Zhang H, et al. Prognostic value of preoperative white blood cell to hemoglobin ratio and fibrinogen to albumin ratio in patients with colorectal cancer. Medicine (Baltimore). 2024 Jan; 103 (3): e37031.","DOI":"10.1097\/MD.0000000000037031"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Ren JY, Wang D, Zhu LH, et al. Combining systemic inflammatory response index and albumin fibrinogen ratio to predict early serious complications and prognosis after resectable gastric cancer. World J Gastrointest Oncol. 2024 Mar; 16 (3): 732-49.","DOI":"10.4251\/wjgo.v16.i3.732"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Fang L, Yan FH, Liu C, et al. Systemic inflammatory biomarkers, especially fibrinogen to albumin ratio, predict prognosis in patients with pancreatic cancer. Cancer Res Treat. 2021 Jan; 53 (1): 131-9.","DOI":"10.4143\/crt.2020.330"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Mai RY, Bai T, Luo XL, et al. Preoperative fibrinogen-to-albumin ratio predicts the prognosis of patients with hepatocellular carcinoma subjected to hepatectomy. BMC Gastroenterol. 2022 May; 22 (1): 261.","DOI":"10.1186\/s12876-022-02328-4"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Austin PC, Lee DS, Fine JP. Introduction to the analysis of survival data in the presence of competing risks. Circulation. 2016 Feb; 133 (6): 601-9.","DOI":"10.1161\/CIRCULATIONAHA.115.017719"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kanda Y. Investigation of the freely available easy-to-use software &apos;EZR&apos; for medical statistics. Bone Marrow Transplant. 2013 Mar; 48 (3): 452-8.","DOI":"10.1038\/bmt.2012.244"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Sahni A, Simpson-Haidaris PJ, Sahni SK, et al. Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2). J Thromb Haemost. 2008 Jan; 6 (1): 176-83.","DOI":"10.1111\/j.1538-7836.2007.02808.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Mei Y, Zhao S, Lu X, et al. Clinical and prognostic significance of preoperative plasma fibrinogen levels in patients with operable breast cancer. PLoS One. 2016 Jan; 11 (1): e0146233.","DOI":"10.1371\/journal.pone.0146233"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Shu YJ, Weng H, Bao RF, et al. Clinical and prognostic significance of preoperative plasma hyperfibrinogenemia in gallbladder cancer patients following surgical resection: a retrospective and in vitro study. BMC Cancer. 2014 Aug; 14: 566.","DOI":"10.1186\/1471-2407-14-566"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Hamar P. Local production of acute phase proteins: A defense reaction of cancer cells to injury with focus on fibrinogen. Int J Mol Sci. 2024 Mar; 25 (6): 3435.","DOI":"10.3390\/ijms25063435"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Qian W, Zhao M, Wang R, et al. Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target. J Hematol Oncol. 2021 Sep; 14 (1): 147.","DOI":"10.1186\/s13045-021-01161-8"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. De Simone G, di Masi A, Ascenzi P. Serum albumin: a multifaced enzyme. Int J Mol Sci. 2021 Sep; 22 (18): 10086.","DOI":"10.3390\/ijms221810086"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Gupta D, Lis CG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr J. 2010 Dec; 9: 69.","DOI":"10.1186\/1475-2891-9-69"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Kannan T, Gazala K. Colorectal Cancer and Nutrition. Nutrients. 2019 Jan; 11 (1):164.","DOI":"10.3390\/nu11010164"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Sun DW, An L, Lv GY. Albumin-fibrinogen ratio and fibrinogen-prealbumin ratio as promising prognostic markers for cancers: an updated meta-analysis. World J Surg Oncol. 2020 Jan; 18 (1): 9.","DOI":"10.1186\/s12957-020-1786-2"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Chen C, Liu Y, Han P, et al. Research progress of preoperative FPR, FAR or AFR in patients with colorectal cancer. Cancer Manag Res. 2021 Feb; 13: 1791-801.","DOI":"10.2147\/CMAR.S292605"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Schellenberg AE, Moravan V, Christian F. A competing risk analysis of colorectal cancer recurrence after curative surgery. BMC Gastroenterology. 2022 Mar; 22 (1): 95.","DOI":"10.1186\/s12876-022-02161-9"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Kanemitsu Y, Shida D, Tsukamoto S, et al. Nomograms predicting survival and recurrence in colonic cancer in the era of complete mesocolic excision. BJS Open. 2019 Apr; 3 (4): 539-48.","DOI":"10.1002\/bjs5.50167"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Akaike H. A new look at the statistical model identification. IEEE Transactions on Automatic Control. 1974; 19: 716-23.","DOI":"10.1109\/TAC.1974.1100705"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Schwarz G. Estimating the dimension of a model. The Annals of Statistics. 1978 Mar; 6 (2): 461-4.","DOI":"10.1214\/aos\/1176344136"}],"container-title":["Journal of the Anus, Rectum and Colon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jarc\/9\/3\/9_2024-112\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T04:22:51Z","timestamp":1753503771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jarc\/9\/3\/9_2024-112\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.23922\/jarc.2024-112","relation":{},"ISSN":["2432-3853"],"issn-type":[{"value":"2432-3853","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"article-number":"2024-112"}}