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Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell. 2010 Mar;140 (6):883-99.","DOI":"10.1016\/j.cell.2010.01.025"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011 Mar;144 (5):646-74.","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Dolan RD, Lim J, McSorley ST, et al. The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis. Sci Rep. 2017 Dec;7 (1):16717.","DOI":"10.1038\/s41598-017-16955-5"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Xie H, Ruan G, Ge Y, et al. Inflammatory burden as a prognostic biomarker for cancer. Clin Nutr. 2022 Jun;41 (6):1236-43.","DOI":"10.1016\/j.clnu.2022.04.019"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Yamashita S, Okugawa Y, Mizuno N, et al. 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Available from: https:\/\/gco.iarc.fr\/ 2022."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Dahdaleh FS, Sherman SK, Poli EC, et al. Obstruction predicts worse long-term outcomes in stage III colon cancer: A secondary analysis of the N0147 trial. Surgery. 2018 Dec;164 (6):1223-9.","DOI":"10.1016\/j.surg.2018.06.044"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Chin CC, Wang JY, Changchien CR, et al. Carcinoma obstruction of the proximal colon cancer and long-term prognosis--obstruction is a predictor of worse outcome in TNM stage II tumor. Int J Colorectal Dis. 2010 Jul;25 (7):817-22.","DOI":"10.1007\/s00384-010-0904-y"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Okuda Y, Shimura T, Yamada T, et al. Colorectal obstruction is a potential prognostic factor for stage II colorectal cancer. Int J Clin Oncol. 2018 Dec;23 (6):1101-11.","DOI":"10.1007\/s10147-018-1307-2"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Teixeira F, Akaishi EH, Ushinohama AZ, et al. Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer? World J Emerg Surg. 2015 Feb;10:5.","DOI":"10.1186\/1749-7922-10-5"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Matsuda A, Miyashita M, Matsumoto S, et al. Comparison of long-term outcomes of colonic stent as &quot;bridge to surgery&quot; and emergency surgery for malignant large-bowel obstruction: a meta-analysis. Ann Surg Oncol. 2015 Feb;22 (2):497-504.","DOI":"10.1245\/s10434-014-3997-7"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Amelung FJ, Burghgraef TA, Tanis PJ, et al. Critical appraisal of oncological safety of stent as bridge to surgery in left-sided obstructing colon cancer; a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2018 Nov;131:66-75.","DOI":"10.1016\/j.critrevonc.2018.08.003"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Ribeiro IB, Bernardo WM, Martins BDC, et al. Colonic stent versus emergency surgery as treatment of malignant colonic obstruction in the palliative setting: a systematic review and meta-analysis. Endosc Int Open. 2018 May;6 (5):E558-67.","DOI":"10.1055\/a-0591-2883"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. van Hooft JE, Veld JV, Arnold D, et al. Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020. Endoscopy. 2020 May;52 (5):389-407.","DOI":"10.1055\/a-1140-3017"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Matsuzawa T, Ishida H, Yoshida S, et al. A Japanese Prospective Multicenter Study of Self-Expandable Metal Stent Placement for Malignant Colorectal Obstruction: Short-Term Safety and Efficacy Within 7 Days of Stent Procedure in 513 Cases. Gastrointest Endosc. 2015 Oct;82 (4):697-707.e1.","DOI":"10.1016\/j.gie.2015.03.1978"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004 Aug;240 (2):205-13.","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"19","unstructured":"19. Edge SB, Byrd DR, Compton CC, et al. AJCC cancer staging manual. 7th ed. New York: Springer; 2010."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kanda Y. Investigation of the freely available easy-to-use software &apos;EZR&apos; for medical statistics. Bone Marrow Transplant. 2013 Mar;48 (3):452-8.","DOI":"10.1038\/bmt.2012.244"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Nishida A, Andoh A. The Role of Inflammation in Cancer: Mechanisms of Tumor Initiation, Progression, and Metastasis. Cells. 2025 Mar;14 (7):488.","DOI":"10.3390\/cells14070488"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Wang B, Lu S, Song Z, et al. Comparison of Clinical Outcomes and Pathological Characteristics of Self-Expandable Stent Bridge to Surgery and Emergency Surgery in Obstructive Colon Cancer. Cancer Manag Res. 2020 Mar;12:1725-32.","DOI":"10.2147\/CMAR.S233456"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Wang J, Chen M, Wei G, et al. From blockage to biology: Unveiling the role of extracellular matrix dynamics in obstructive colorectal cancer pathogenesis. Pathol Res Pract. 2025 Jun;270:155994.","DOI":"10.1016\/j.prp.2025.155994"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Eto S, Kawahara H, Matsumoto T, et al. Preoperative Neutrophil-Lymphocyte Ratio Is a Predictor of Bowel Obstruction Due to Colorectal Cancer Growth. Anticancer Res. 2019 Jun;39 (6):3185-9.","DOI":"10.21873\/anticanres.13456"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Yin C, Okugawa Y, Kitajima T, et al. Clinical Significance of the Preoperative Inflammatory Burden Index in Esophageal Cancer. Oncology. 2024;102 (7):556-64.","DOI":"10.1159\/000535727"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Aoyama T, Maezawa Y, Hashimoto I, et al. Inflammatory Burden Index Is an Independent Prognostic Factor for Esophageal Cancer Patients Who Receive Curative Treatment. In Vivo. 2024 Nov-Dec;38 (6):2928-34.","DOI":"10.21873\/invivo.13775"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Song R, Ni H, Huang J, et al. Prognostic Value of Inflammation-Immunity-Nutrition Score and Inflammatory Burden Index for Hepatocellular Carcinoma Patients After Hepatectomy. J Inflamm Res. 2022 Nov;15:6463-79.","DOI":"10.2147\/JIR.S386407"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Taniai T, Haruki K, Furukawa K, et al. The novel index using preoperative C-reactive protein and neutrophil-to-lymphocyte ratio predicts poor prognosis in patients with pancreatic cancer. Int J Clin Oncol. 2021 Oct;26 (10):1922-8.","DOI":"10.1007\/s10147-021-01964-2"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. McSorley ST, Horgan PG, McMillan DC. The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: A systematic review and meta-analysis. Crit Rev Oncol Hematol. 2016 Jan;97:168-77.","DOI":"10.1016\/j.critrevonc.2015.08.013"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Lawler J, Choynowski M, Bailey K, et al. Meta-analysis of the impact of postoperative infective complications on oncological outcomes in colorectal cancer surgery. BJS Open. 2020 Oct;4 (5):737-47.","DOI":"10.1002\/bjs5.50302"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Jin Y, Sun Y, Shi X, et al. Prognostic value of circulating C-reactive protein levels in patients with non-small cell lung cancer: a systematic review with meta-analysis. J Cancer Res Ther. 2014 Nov;10 Suppl:C160-6.","DOI":"10.4103\/0973-1482.145854"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Allin KH, Nordestgaard BG. Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer. Crit Rev Clin Lab Sci. 2011 Jul-Aug;48 (4):155-70.","DOI":"10.3109\/10408363.2011.599831"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Zhou K, Li C, Chen T, et al. C-reactive protein levels could be a prognosis predictor of prostate cancer: A meta-analysis. Front Endocrinol (Lausanne). 2023 Feb;14:1111277.","DOI":"10.3389\/fendo.2023.1111277"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Riedl JM, Barth DA, Brueckl WM, et al. C-Reactive Protein (CRP) Levels in Immune Checkpoint Inhibitor Response and Progression in Advanced Non-Small Cell Lung Cancer: A Bi-Center Study. Cancers (Basel). 2020 Aug;12 (8):2319.","DOI":"10.3390\/cancers12082319"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Zhang X, Zhang W, Yuan X, et al. Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review). Int J Oncol. 2016 Sep;49 (3):857-67.","DOI":"10.3892\/ijo.2016.3616"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Iseki Y, Shibutani M, Maeda K, et al. The impact of the preoperative peripheral lymphocyte count and lymphocyte percentage in patients with colorectal cancer. Surg Today. 2017 Jun;47 (6):743-54.","DOI":"10.1007\/s00595-016-1433-2"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Sato R, Oikawa M, Kakita T, et al. The prognostic value of the prognostic nutritional index and inflammation-based markers in obstructive colorectal cancer. Surg Today. 2020 Oct;50 (10):1272-81.","DOI":"10.1007\/s00595-020-02007-5"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Sato R, Oikawa M, Kakita T, et al. The Controlling Nutritional Status (CONUT) Score as a prognostic factor for obstructive colorectal cancer patients received stenting as a bridge to curative surgery. Surg Today. 2021 Jan;51 (1):144-52.","DOI":"10.1007\/s00595-020-02066-8"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Sato R, Oikawa M, Kakita T, et al. A decreased preoperative platelet-to-lymphocyte ratio, systemic immune-inflammation index, and pan-immune-inflammation value are associated with the poorer survival of patients with a stent inserted as a bridge to curative surgery for obstructive colorectal cancer. Surg Today. 2023 Apr;53 (4):409-19.","DOI":"10.1007\/s00595-022-02575-8"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Hu Y, Fan J, Xv Y, et al. 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