{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T06:00:43Z","timestamp":1784959243277,"version":"3.55.0"},"reference-count":33,"publisher":"The Japan Society of Coloproctology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Anus Rectum Colon"],"published-print":{"date-parts":[[2026,7,25]]},"DOI":"10.23922\/jarc.2025-087","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T22:11:09Z","timestamp":1784931069000},"page":"410-420","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Doppler Ultrasonography with Superb Microvascular Imaging for Intestinal Perfusion Assessment in Colorectal Cancer Surgery: A Prospective Pilot Study"],"prefix":"10.23922","volume":"10","author":[{"given":"Atsushi","family":"Hirata","sequence":"first","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaku","family":"Ohira","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoko","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuro","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Tochigi","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Hayano","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Uesato","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Kainuma","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michihiro","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Frontier Surgery, Chiba University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10009","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Litchinko A, Buchs N, Balaphas A, et al. Score prediction of anastomotic leak in colorectal surgery: a systematic review. Surg Endosc. 2024 Apr;38 (4):1723-30.","DOI":"10.1007\/s00464-024-10705-1"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Degiuli M, Elmore U, De Luca R, et al. Risk factors for anastomotic leakage after anterior resection for rectal cancer (RALAR study): A nationwide retrospective study of the Italian Society of Surgical Oncology Colorectal Cancer Network Collaborative Group. Colorectal Dis. 2022 Mar;24 (3):264-76.","DOI":"10.1111\/codi.15997"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Phan K, Oh L, Ctercteko G, et al. Does a stoma reduce the risk of anastomotic leak and need for re-operation following low anterior resection for rectal cancer: systematic review and meta-analysis of randomized controlled trials. J Gastrointest Oncol. 2019 Apr;10 (2):179-87.","DOI":"10.21037\/jgo.2018.11.07"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Shiomi A, Ito M, Maeda K, et al. Effects of a diverting stoma on symptomatic anastomotic leakage after low anterior resection for rectal cancer: a propensity score matching analysis of 1,014 consecutive patients. J Am Coll Surg. 2015 Feb;220 (2):186-94.","DOI":"10.1016\/j.jamcollsurg.2014.10.017"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ha GW, Kim JH, Lee MR. Oncologic Impact of Anastomotic Leakage Following Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis. Ann Surg Oncol. 2017 Oct;24 (11):3289-99.","DOI":"10.1245\/s10434-017-5881-8"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Jafari MD, Pigazzi A, McLemore EC, et al. Perfusion Assessment in Left-Sided\/Low Anterior Resection (PILLAR III): A Randomized, Controlled, Parallel, Multicenter Study Assessing Perfusion Outcomes With PINPOINT Near-Infrared Fluorescence Imaging in Low Anterior Resection. Dis Colon Rectum. 2021 Aug 1;64 (8):995-1002.","DOI":"10.1097\/DCR.0000000000002007"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Watanabe J, Takemasa I, Kotake M, et al. Blood Perfusion Assessment by Indocyanine Green Fluorescence Imaging for Minimally Invasive Rectal Cancer Surgery (EssentiAL trial): A Randomized Clinical Trial. Ann Surg. 2023 Oct 1;278 (4):e688-94.","DOI":"10.1097\/SLA.0000000000005907"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Iwamoto M, Ueda K, Kawamura J. A Narrative Review of the Usefulness of Indocyanine Green Fluorescence Angiography for Perfusion Assessment in Colorectal Surgery. Cancers (Basel). 2022 Nov 16;14 (22):5623.","DOI":"10.3390\/cancers14225623"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Katayama H, Yamaguchi K, Kozuka T, et al. Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. Radiology. 1990 Jun;175 (3):621-8.","DOI":"10.1148\/radiology.175.3.2343107"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Emile SH, Khan SM, Wexner SD. Impact of change in the surgical plan based on indocyanine green fluorescence angiography on the rates of colorectal anastomotic leak: a systematic review and meta-analysis. Surg Endosc. 2022 Apr;36 (4):2245-57.","DOI":"10.1007\/s00464-021-08973-2"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Uppal JS, Meng E, Caycedo-Marulanda A. Current applications of indocyanine green fluorescence in colorectal surgery: a narrative review. Ann Laparosc Endosc Surg. 2023 Jul 30;8:18.","DOI":"10.21037\/ales-22-84"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Higashijima J, Shimada M, Yoshikawa K, et al. Usefulness of blood flow evaluation by indocyanine green fluorescence system in laparoscopic anterior resection. J Med Invest. 2019;66 (1.2):65-9.","DOI":"10.2152\/jmi.66.65"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Depalma N, D&apos;Ugo S, Manoochehri F, et al. NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery. Cancers (Basel). 2023 Nov 22;15 (23):5528.","DOI":"10.3390\/cancers15235528"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Wang LW, Kesteven SH, Huttner IG, et al. High-Frequency Echocardiography - Transformative Clinical and Research Applications in Humans, Mice, and Zebrafish. Circ J. 2018 Feb 23;82 (3):620-8.","DOI":"10.1253\/circj.CJ-18-0027"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Fu Z, Zhang J, Lu Y, et al. Clinical Applications of Superb Microvascular Imaging in the Superficial Tissues and Organs: A Systematic Review. Acad Radiol. 2021 May;28 (5):694-703.","DOI":"10.1016\/j.acra.2020.03.032"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Lucas VS, Burk RS, Creehan S, et al. Utility of high-frequency ultrasound: moving beyond the surface to detect changes in skin integrity. Plast Surg Nurs. 2014 Jan-Mar;34 (1):34-8.","DOI":"10.1097\/PSN.0000000000000031"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Jasionyte G, Seskute G, Rugiene R, et al. The Promising Role of a Superb Microvascular Imaging Technique in the Evaluation of Raynaud&apos;s Syndrome in Systemic Sclerosis: Theory and Practical Challenges. Diagnostics (Basel). 2021 Sep 22;11 (10):1743.","DOI":"10.3390\/diagnostics11101743"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Arai S, Ohira G, Hirata A, et al. Real-time visualization of human colonic vascular architecture using 33-MHz high-frequency ultrasound and superb microvascular imaging. J Med Ultrason. 2026;53:239-241.","DOI":"10.1007\/s10396-025-01603-7"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Japanese Society for Cancer of the C, Rectum. Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma: the 3d English Edition [Secondary Publication]. J Anus Rectum Colon. 2019;3 (4):175-95.","DOI":"10.23922\/jarc.2019-018"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kanniyappan U, Wang B, Yang C, et al. Performance test methods for near-infrared fluorescence imaging. Med Phys. 2020 Aug;47 (8):3389-401.","DOI":"10.1002\/mp.14189"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Gitto S, Messina C, Chianca V, et al. Superb microvascular imaging (SMI) in the evaluation of musculoskeletal disorders: a systematic review. Radiol Med. 2020 May;125 (5):481-90.","DOI":"10.1007\/s11547-020-01141-x"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Aziz MU, Eisenbrey JR, Deganello A, et al. Microvascular Flow Imaging: A State-of-the-Art Review of Clinical Use and Promise. Radiology. 2022 Nov;305 (2):250-64.","DOI":"10.1148\/radiol.213303"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Jensen JA. Medical ultrasound imaging. Prog Biophys Mol Biol. 2007 Jan-Apr;93 (1-3):153-65.","DOI":"10.1016\/j.pbiomolbio.2006.07.025"},{"key":"24","unstructured":"24. Odaka H. [SMI Angio mode with improved blood-flow separation capability]. Japanese Journal of Medical Ultrasound Technology. 2025;50 (6):601-6. Japanese."},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Son GM, Kwon MS, Kim Y, et al. Quantitative analysis of colon perfusion pattern using indocyanine green (ICG) angiography in laparoscopic colorectal surgery. Surg Endosc. 2019 May;33 (5):1640-9.","DOI":"10.1007\/s00464-018-6439-y"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Paramasivam R, Jaensch C, Madsen AH, et al. Intraoperative assessment of anastomotic microcirculation during right hemicolectomy with real-time laser speckle contrast imaging is safe and feasible. Colorectal Dis. 2025 Jul;27 (7):e70162.","DOI":"10.1111\/codi.70162"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Kojima S, Sakamoto T, Matsui Y, et al. Clinical efficacy of bowel perfusion assessment during laparoscopic colorectal resection using laser speckle contrast imaging: A matched case-control study. Asian J Endosc Surg. 2020 Jul;13 (3):329-35.","DOI":"10.1111\/ases.12759"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Yoshinaka H, Shimomura M, Egi H, et al. Non-invasive measurement of intestinal tissue oxygen saturation for evaluation of reconstructed blood flow in rectal cancer surgery: HiSCO-09 study. Br J Surg. 2023 Nov 9;110 (12):1769-73.","DOI":"10.1093\/bjs\/znad315"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Hasegawa H, Takeshita N, Ito M. Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model. BMC Surg. 2020 Oct 22;20 (1):250.","DOI":"10.1186\/s12893-020-00913-6"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Du CZ, Fan ZH, Yang YF, et al. Value of intra-operative Doppler sonographic measurements in predicting post-operative anastomotic leakage in rectal cancer: a prospective pilot study. Chin Med J (Engl). 2019 Sep 20;132 (18):2168-76.","DOI":"10.1097\/CM9.0000000000000410"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Kachlik D, Baca V, Stingl J. The spatial arrangement of the human large intestinal wall blood circulation. J Anat. 2010 Mar;216 (3):335-43.","DOI":"10.1111\/j.1469-7580.2009.01199.x"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Griffiths JD. Extramural and intramural blood-supply of colon. Br Med J. 1961 Feb 4;1 (5222):323-6.","DOI":"10.1136\/bmj.1.5222.323"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Jansen-Winkeln B, Germann I, K\u00f6hler H, et al. Comparison of hyperspectral imaging and fluorescence angiography for the determination of the transection margin in colorectal resections-a comparative study. Int J Colorectal Dis. 2021 Feb;36 (2):283-91.","DOI":"10.1007\/s00384-020-03755-z"}],"container-title":["Journal of the Anus, Rectum and Colon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jarc\/10\/3\/10_2025-087\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:11:01Z","timestamp":1784956261000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jarc\/10\/3\/10_2025-087\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,25]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.23922\/jarc.2025-087","relation":{},"ISSN":["2432-3853"],"issn-type":[{"value":"2432-3853","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,25]]},"article-number":"2025-087"}}