{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T04:02:13Z","timestamp":1749268933047,"version":"3.41.0"},"reference-count":37,"publisher":"Gobierno de Navarra","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An Sist Sanit Navar"],"published-print":{"date-parts":[[2020,4,20]]},"DOI":"10.23938\/assn.0757","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T13:17:32Z","timestamp":1583500652000},"page":"51-56","source":"Crossref","is-referenced-by-count":3,"title":["Impact of opioid free anaesthesia in bariatric surgery"],"prefix":"10.23938","volume":"43","member":"10024","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"ODERDA GM, SAID Q, EVANS RS, STODDARD GJ, LLOYD J, JACKSON K et al. Opioid-related adverse drug events in surgical hospitalizations: impact on costs and length of stay. Ann Pharmacother 2007; 41: 400-407. https:\/\/doi.org\/10.1345\/aph.1H386","DOI":"10.1345\/aph.1H386"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. WEINBROUM AA. Role of anaesthetics and opioids in perioperative hyperalgesia. Eur J Anaesthesiol 2015; 32: 230-231. https:\/\/doi.org\/10.1097\/EJA.0000000000000231","DOI":"10.1097\/EJA.0000000000000231"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. FUNK RD, HILLIARD P, RAMACHANDRAN SK. Perioperative opioid usage. Plast Reconstr Surg 2014; 134: 32S-39S. https:\/\/doi.org\/10.1097\/prs.0000000000000680","DOI":"10.1097\/PRS.0000000000000680"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. MULIER JP. Perioperative opioids aggravate obstructive breathing in sleep apnea syndrome. Curr Opin Anaesthesiol 2016; 29: 129-133. https:\/\/doi.org\/10.1097\/aco.0000000000000281","DOI":"10.1097\/ACO.0000000000000281"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. DHONNEUR G, COMBES X, LEROUX B, DUVALDESTIN P. Postoperative obstructive apnea. Anesth Analg 1999; 89: 762-767. https:\/\/doi.org\/10.1097\/00000539-199909000-00045","DOI":"10.1097\/00000539-199909000-00045"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. BENUMOF JL. Obstructive sleep apnea in the adult obese patient: implications for airway management. J Clin Anesth 2001; 13: 144-156. https:\/\/doi.org\/10.1016\/s0952-8180(01)00232-x","DOI":"10.1016\/S0952-8180(01)00232-X"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. GOLD AR, GOLD MS, HARRIS KW, ESPELETA VJ, AMIN MM, BRODERICK JE. Hypersomnolence, insomnia and the pathophysiology of upper airway resistance syndrome. Sleep Med 2008; 9: 675-683. https:\/\/doi.org\/10.1016\/j.sleep.2007.08.013","DOI":"10.1016\/j.sleep.2007.08.013"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8. ROSE DK, COHEN MM, WIGGLESWORTH DF, DEBOER DP. Critical respiratory events in the Postanesthesia Care Unit. Anesthesiology 1994; 81: 410-418. https:\/\/doi.org\/10.1097\/00000542-199408000-00020","DOI":"10.1097\/00000542-199408000-00020"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9. BERCAULT N, BOULAIN T, KUTEIFAN K, WOLF M, RUNGE I, FLEURY JC. Obesity-related excess mortality rate in an adult intensive care unit: a risk-adjusted matched cohort study. Crit Care Med 2004; 32: 998-1003. https:\/\/doi.org\/10.1097\/01.ccm.0000119422.93413.08","DOI":"10.1097\/01.CCM.0000119422.93413.08"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. GUPTA RM, PARVIZI J, HANSSEN AD, GAY PC. Postoperative complications in patients with obstructive sleep apnea syndrome undergoing hip or knee replacement: a case-control study. Mayo Clin Proc 2001; 76: 897-905. https:\/\/doi.org\/10.4065\/76.9.897","DOI":"10.4065\/76.9.897"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. TURAN A, YOU J, EGAN C, FU A, KHANNA A, ESHRAGHI Y et al. Chronic intermittent hypoxia is independently associated with reduced postoperative opioid consumption in bariatric patients suffering from sleep-disordered breathing. PLoS One 2015; 10: e0127809. https:\/\/doi.org\/10.1371\/journal.pone.0127809","DOI":"10.1371\/journal.pone.0127809"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. GALLAGHER SF, HAINES KL, OSTERLUND LG, MULLEN M, DOWNS JB. Postoperative hypoxemia: common, undetected, and unsuspected after bariatric surgery. J Surg Res 2010; 159: 622-626. https:\/\/doi.org\/10.1016\/j.jss.2009.09.003","DOI":"10.1016\/j.jss.2009.09.003"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. AHMAD S, NAGLE A, MCCARTHY RJ, FITZGERALD PC, SULLIVAN JT, PRYSTOWSKY J. Postoperative hypoxemia in morbidly obese patients with and without obstructive sleep apnea undergoing laparoscopic bariatric surgery. Anesth Analg 2008; 107: 138-143. https:\/\/doi.org\/10.1213\/ane.0b013e318174df8b","DOI":"10.1213\/ane.0b013e318174df8b"},{"key":"ref13","unstructured":"14. World Health Organization. Global status report on alcohol and health 2014. Poznyak V, Rekve D, editors. Luxembourg: World Health Organization, 2014. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/112736\/9789240692763_eng.pdf?sequence=1"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15. NG M, FLEMING T, ROBINSON M, THOMSON B, GRAETZ N, MARGONO C et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014; 384: 766-781. https:\/\/doi.org\/10.1016\/S0140-6736(14)60460-8","DOI":"10.1016\/S0140-6736(14)60460-8"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. BERRINGTON DE GONZALEZ A, HARTGE P, CERHAN JR, FLINT AJ, HANNAN L, MACINNIS RJ et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 2010; 363: 2211-2219. https:\/\/doi.org\/10.1056\/NEJMoa1000367","DOI":"10.1056\/NEJMoa1000367"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17. BUCHWALD H, AVIDOR Y, BRAUNWALD E, JENSEN MD, PORIES W, FAHRBACH K et al. Bariatric surgery. JAMA 2004; 292: 1724. https:\/\/doi.org\/10.1001\/jama.292.14.1724","DOI":"10.1001\/jama.292.14.1724"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"18. CHRISTOU NV, SAMPALIS JS, LIBERMAN M, LOOK D, AUGER S, MCLEAN APH et al. Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg 2004; 240: 416-424. https:\/\/doi.org\/10.1097\/01.sla.0000137343.63376.19","DOI":"10.1097\/01.sla.0000137343.63376.19"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. THORELL A, MACCORMICK AD, AWAD S, REYNOLDS N, ROULIN D, DEMARTINES N et al. Guidelines for perioperative care in bariatric surgery: enhanced recovery after surgery (ERAS) society recommendations. World J Surg 2016; 40: 2065-2083. https:\/\/doi.org\/10.1007\/s00268-016-3492-3","DOI":"10.1007\/s00268-016-3492-3"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. MA\u0141CZAK P, PISARSKA M, PIOTR M, WYSOCKI M, BUDZY\u0143SKI A, P\u0118DZIWIATR M. Enhanced recovery after bariatric surgery: systematic review and meta-analysis. Obes Surg 2017; 27: 226-235. https:\/\/doi.org\/10.1007\/s11695-016-2438-z","DOI":"10.1007\/s11695-016-2438-z"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. PIERRE S, BENAIS H, POUYMAYOU J. Apfel's simplified score may favourably predict the risk of postoperative nausea and vomiting. Can J Anesth 2002; 49: 237-242. https:\/\/doi.org\/10.1007\/bf03020521","DOI":"10.1007\/BF03020521"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22. VEIGA-GIL L, PUEYO J, L\u00d3PEZ-OLAONDO L. N\u00e1useas y v\u00f3mitos postoperatorios: fisiopatolog\u00eda, factores de riesgo, profilaxis y tratamiento . Rev Esp Anestesiol Reanim 2017; 64: 223-232. https:\/\/doi.org\/10.1016\/j.redar.2016.10.001","DOI":"10.1016\/j.redar.2016.10.001"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23. HALLIDAY TA, SUNDQVIST J, HULTIN M, WALLD\u00c9N J. Post-operative nausea and vomiting in bariatric surgery patients: an observational study. Acta Anaesthesiol Scand 2017; 61: 471-479. https:\/\/doi.org\/10.1111\/aas.12884","DOI":"10.1111\/aas.12884"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24. RAVESLOOT MJL, VAN MAANEN JP, HILGEVOORD AAJ, VAN WAGENSVELD BA, DE VRIES N. Obstructive sleep apnea is underrecognized and underdiagnosed in patients undergoing bariatric surgery. Eur Arch Oto-Rhino-Laryngology 2012; 269: 1865-1871. https:\/\/doi.org\/10.1007\/s00405-012-1948-0","DOI":"10.1007\/s00405-012-1948-0"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25. YOUNG T, PEPPARD PE, TAHERI S. Excess weight and sleep-disordered breathing. J Appl Physiol 2005; 99: 1592-1599. https:\/\/doi.org\/10.1152\/japplphysiol.00587.2005","DOI":"10.1152\/japplphysiol.00587.2005"},{"key":"ref25","unstructured":"26. SAMUELS D, ABOU-SAMRA A, DALVI P, MANGAR D, CAMPORESI EM. Opioid-free anesthesia results in reduced post-operative opioid consumption. J Clin Anesth Pain Med 2017; 1: 005."},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"27. BHARDWAJ S, GARG K, DEVGAN S. Comparison of opioid-based and opioid-free TIVA for laparoscopic urological procedures in obese patients. J Anaesthesiol Clin Pharmacol 2019; 35: 481-486. https:\/\/doi.org\/10.4103\/joacp.joacp_382_18","DOI":"10.4103\/joacp.JOACP_382_18"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"28. FELD JM, LAURITO CE, BECKERMAN M, VINCENT J, HOFFMAN WE. Non-opioid analgesia improves pain relief and decreases sedation after gastric bypass surgery. Can J Anesth 2003; 50: 336-341. https:\/\/doi.org\/10.1007\/bf03021029","DOI":"10.1007\/BF03021029"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"29. SALEM AM, HAFEZ MML, ELDIN AS, HAGRAS AM. Opioid-free anesthesia for laparoscopic hysterectomy: is it appropriate? J Anesth Inten Care Med 2019; 9: 555757. https:\/\/doi.org\/10.19080\/JAICM.2019.09.555757","DOI":"10.19080\/JAICM.2019.09.555757"},{"key":"ref29","unstructured":"30. MULIER JP, WOUTERS R, DILLEMANS B, DEKOCK M. A randomized controlled, double-blind trial evaluating the effect of opioid-free versus opioid general anaesthesia on postoperative pain and discomfort measured by the QoR-40. J Clin Anesth Pain Med 2018; 2: 015."},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"31. HAKIM KYK, WAHBA ZWB. Opioid-free total intravenous anesthesia improves postoperative quality of recovery after ambulatory gynecologic laparoscopy. Anesth Essays Res 2019; 13: 199-203. https:\/\/doi.org\/10.4103\/aer.aer_74_19","DOI":"10.4103\/aer.AER_74_19"},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"32. LAM KKY, MUI WLM. Multimodal analgesia model to achieve low postoperative opioid requirement following bariatric surgery. Hong Kong Med J 2016; 22 : 428-434. https:\/\/doi.org\/10.12809\/hkmj154769","DOI":"10.12809\/hkmj154769"},{"key":"ref32","doi-asserted-by":"publisher","unstructured":"33. BAKAN M, UMUTOGLU T, TOPUZ U, UYSAL H, BAYRAM M, KADIOGLU H et al. Anestesia venosa total livre de opioides, com infus\u00f5es de propofol, dexmedetomidina e lidoca\u00edna para colecistectomia laparosc\u00f3pica: Estudo prospectivo, randomizado e duplo-cego. Rev Bras Anestesiol 2015; 65: 191-199. https:\/\/doi.org\/10.1016\/j.bjane.2014.05.001","DOI":"10.1016\/j.bjane.2014.05.001"},{"key":"ref33","doi-asserted-by":"publisher","unstructured":"34. ZIEMANN-GIMMEL P, GOLDFARB AA, KOPPMAN J, MAREMA RT. Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis. Br J Anaesth 2014; 112: 906-911. https:\/\/doi.org\/10.1093\/bja\/aet551","DOI":"10.1093\/bja\/aet551"},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"35. TAYLOR S, KIRTON OC, STAFF I, KOZOL RA. Postoperative day one: a high risk period for respiratory events. Am J Surg 2005; 190: 752-756. https:\/\/doi.org\/10.1016\/j.amjsurg.2005.07.015","DOI":"10.1016\/j.amjsurg.2005.07.015"},{"key":"ref35","doi-asserted-by":"publisher","unstructured":"36. MULIER JP, DILLEMANS B. Anaesthetic factors affecting outcome after bariatric surgery, a retrospective levelled regression analysis. Obes Surg 2019; 29: 1841-1850 https:\/\/doi.org\/10.1007\/s11695-019-03763-1","DOI":"10.1007\/s11695-019-03763-1"},{"key":"ref36","doi-asserted-by":"publisher","unstructured":"37. D\u00cdAZ-CRESPO J, MALO-MANSO A, BUSTAMANTE-DOM\u00cdNGUEZ C, ESCALONA-BELMONTE JJ, CRUZ-MA\u00d1AS J, GUERRERO-ORRIACH JL. Laparotomy in a patient under opioid-free anaesthesia. An Sist Sanit Navar 2018; 41: 259-262. https:\/\/doi.org\/10.23938\/ASSN.0294","DOI":"10.23938\/ASSN.0294"}],"container-title":["Anales del Sistema Sanitario de Navarra"],"original-title":[],"link":[{"URL":"https:\/\/recyt.fecyt.es\/index.php\/ASSN\/article\/view\/76328\/49225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T05:58:40Z","timestamp":1749189520000},"score":1,"resource":{"primary":{"URL":"https:\/\/recyt.fecyt.es\/index.php\/ASSN\/article\/view\/76328\/49225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,20]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,4]]}},"URL":"https:\/\/doi.org\/10.23938\/assn.0757","relation":{},"ISSN":["1137-6627"],"issn-type":[{"type":"print","value":"1137-6627"}],"subject":[],"published":{"date-parts":[[2020,4,20]]}}}