{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:49:27Z","timestamp":1788778167394,"version":"build-2803163510"},"reference-count":0,"publisher":"Health Promotion and Chronic Disease Prevention Branch (HPCDP) Public Health Agency of Canada","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Health Promot Chronic Dis Prev Can"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<sec>\n         <title>Introduction<\/title>\n         <p>Excess body weight (body mass index [BMI] \u2265 25.00 kg\/m2) is an established\nrisk factor for diabetes, hypertension and cardiovascular disease, but its relationship\nto cancer is lesser-known. This study used population attributable fractions (PAFs)\nto estimate the cancer burden attributable to excess body weight in Canadian adults\n(aged 25+ years) in 2010.<\/p>\n       <\/sec>\n       <sec>\n         <title>Methods<\/title>\n         <p>We estimated PAFs using relative risk (RR) estimates from the World Cancer\nResearch Fund International Continuous Update Project, BMI-based estimates of overweight\n(25.00 kg\/m2\u201329.99 kg\/m2) and obesity (30.00+ kg\/m2) from the 2000\u20132001 Canadian\nCommunity Health Survey, and cancer case counts from the Canadian Cancer Registry.\nPAFs were based on BMI corrected for the bias in self-reported height and weight.<\/p>\n       <\/sec>\n       <sec>\n         <title>Results<\/title>\n         <p>In Canada in 2010, an estimated 9645 cancer cases were attributable to excess\nbody weight, representing 5.7% of all cancer cases (males 4.9%, females 6.5%). When\nlimiting the analysis to types of cancer associated with high BMI, the PAF increased to\n14.9% (males 17.5%, females 13.3%). Types of cancer with the highest PAFs were\nesophageal adenocarcinoma (42.2%), kidney (25.4%), gastric cardia (20.7%), liver\n(20.5%), colon (20.5%) and gallbladder (20.2%) for males, and esophageal adenocarcinoma\n(36.1%), uterus (35.2%), gallbladder (23.7%) and kidney (23.0%) for females.\nTypes of cancer with the greatest number of attributable cases were colon (1445), kidney\n(780) and advanced prostate (515) for males, and uterus (1825), postmenopausal\nbreast (1765) and colon (675) for females. Irrespective of sex or type of cancer, PAFs\nwere highest in the Prairies (except Alberta) and the Atlantic region and lowest in\nBritish Columbia and Quebec.<\/p>\n       <\/sec>\n\t   <sec>\n         <title>Conclusion<\/title>\n         <p>The cancer burden attributable to excess body weight is substantial and\nwill continue to rise in the near future because of the rising prevalence of overweight\nand obesity in Canada.<\/p>\n       <\/sec>","DOI":"10.24095\/hpcdp.37.7.01","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T18:53:49Z","timestamp":1499712829000},"page":"205-214","source":"Crossref","is-referenced-by-count":13,"title":["Cancers attributable to excess body weight in Canada in 2010"],"prefix":"10.24095","volume":"37","author":[{"given":"Dianne","family":"Zakaria","sequence":"first","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Shaw","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10188","container-title":["Health Promotion and Chronic Disease Prevention in Canada"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.canada.ca\/en\/public-health\/services\/reports-publications\/health-promotion-chronic-disease-prevention-canada-research-policy-practice\/vol-37-no-7-2017\/cancers-attributable-excess-body-weight-canada-2010.html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T19:41:45Z","timestamp":1512589305000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.canada.ca\/en\/public-health\/services\/reports-publications\/health-promotion-chronic-disease-prevention-canada-research-policy-practice\/vol-37-no-7-2017\/cancers-attributable-excess-body-weight-canada-2010.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":0,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.24095\/hpcdp.37.7.01","archive":["Internet Archive"],"relation":{},"ISSN":["2368-738X"],"issn-type":[{"value":"2368-738X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}