{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:43:38Z","timestamp":1782549818446,"version":"3.54.5"},"reference-count":0,"publisher":"Health Promotion and Chronic Disease Prevention Branch (HPCDP) Public Health Agency of Canada","issue":"7\/8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Health Promot Chronic Dis Prev Can"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<sec>\n         <title>Introduction<\/title>\n         <p>South Asians have a higher than average risk of developing type 2 diabetes.\nWe ascertained the effectiveness of CANRISK, an existing diabetes risk assessment\ntool, examining its sensitivity and specificity at two different predetermined scoring\ncut-off points comparing those participants under the age of 40 and those 40 and over.\nWe examined the predictive ability of a model based on CANRISK variables, comparing\nethno-specific body mass index (BMI) and waist circumference (WC) cut-off points with\nthe original BMI and WC cut-off points to see if predictive ability could be improved for\nthis population.<\/p>\n       <\/sec>\n       <sec>\n         <title>Methods<\/title>\n         <p>Canadian South Asians of unknown diabetes status, age 18 to 78, were\nrecruited across seven provinces from various community or health centers. CANRISK\nvariables were collected followed by oral glucose tolerance testing. Descriptive analysis,\nlogistic regression including alternative ethno-specific BMI and WC cut-off points, and\nsensitivity and specificity analyses were performed.<\/p>\n       <\/sec>\n       <sec>\n         <title>Results<\/title>\n         <p>832 participants were recruited (584 under age 40). Using the entire study\nsample, logistic regression models including CANRISK variables predicted dysglycemia\neffectively (AUC of 0.80). However, by using alternative BMI\/WC cut-off points with the\nscoring algorithm, predictive power via AUC was not improved. Sensitivity and specificity\nof CANRISK using the original pre-determined \u201chigh risk\u201d cut-off point of 33 points\nin individuals age 40 years or over were 93% and 35%, respectively; in individuals\nunder 40, these were 33% and 92%, respectively. Using the lower pre-determined\n\u201cmoderate risk\u201d cut-off point of 21 points improved the sensitivity to 77% and specificity\nto 53% in the younger age group.<\/p>\n       <\/sec>\n\t   <sec>\n         <title>Conclusion<\/title>\n         <p>The existing CANRISK is an adequate risk assessment tool for dysglycemia\nin Canadian South Asians for those age 40 years and over; however, the tool does\nnot work as well for individuals under 40. The lower cut-off of 21 points may be warranted\nfor younger individuals to minimize false negatives. Ethno-specific BMI\/WC cutoff\npoints did not improve predictive ability of the CANRISK scoring algorithm as\nmeasured by AUC.<\/p>\n       <\/sec>","DOI":"10.24095\/hpcdp.38.7\/8.03","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T16:16:00Z","timestamp":1533312960000},"page":"286-294","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of the CANRISK tool in the identification of dysglycemia in a Canadian South Asian Population"],"prefix":"10.24095","volume":"38","author":[{"given":"Gina","family":"Agarwal","sequence":"first","affiliation":[{"name":"Departments of Family Medicine and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Lemieux","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"},{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Rogers Van Katwyk","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Mao","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Orpana","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"},{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maylene","family":"Fong","sequence":"additional","affiliation":[{"name":"Vancouver Coastal Health, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Morrison","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10188","container-title":["Health Promotion and Chronic Disease Prevention in Canada"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.canada.ca\/en\/public-health\/services\/reports-publications\/health-promotion-chronic-disease-prevention-canada-research-policy-practice\/vol-38-no-7-8-2018\/canrisk-indentification-dysglycemia-canadian-south-asian-population.html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T16:16:02Z","timestamp":1533312962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.canada.ca\/en\/public-health\/services\/reports-publications\/health-promotion-chronic-disease-prevention-canada-research-policy-practice\/vol-38-no-7-8-2018\/canrisk-indentification-dysglycemia-canadian-south-asian-population.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":0,"journal-issue":{"issue":"7\/8"},"URL":"https:\/\/doi.org\/10.24095\/hpcdp.38.7\/8.03","archive":["Internet Archive"],"relation":{},"ISSN":["2368-738X"],"issn-type":[{"value":"2368-738X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}