{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:06:28Z","timestamp":1790723188792,"version":"4.1.0"},"reference-count":40,"publisher":"Korea Disease Control and Prevention Agency","issue":"1","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["kcdcphrp.org"],"crossmark-restriction":true},"short-container-title":["Osong Public Health Res Perspect"],"published-print":{"date-parts":[[2019,2,28]]},"DOI":"10.24171\/j.phrp.2019.10.1.03","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T04:54:09Z","timestamp":1550811249000},"page":"6-11","update-policy":"https:\/\/doi.org\/10.24171\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains"],"prefix":"10.24171","volume":"10","author":[{"given":"Firouzeh","family":"Farahtaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Alizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Gholami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Tahamtan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadegh","family":"Shirian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Fazeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Sasan Mozaffari","family":"Nejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Gorji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid Mahmoudzadeh","family":"Niknam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Ghaemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"31909","reference":[{"key":"ref1","first-page":"267","volume-title":"Rabies pathogenesis","author":"Jackson","year":"2002"},{"key":"ref2","first-page":"481","volume-title":"A review of the economics of the prevention and control of rabies. Part 2: Rabies in dogs, livestock and wildlife","author":"Meltzer","year":"1998"},{"key":"ref3","first-page":"222","volume-title":"Global infectious disease surveillance","author":"Martinez","year":"2000"},{"key":"ref4","first-page":"S20","volume-title":"Rabies and rabies research: past, present and future","author":"Fu","year":"1997"},{"key":"ref5","first-page":"101","volume-title":"Human rabies: a disease of complex neuropathogenetic mechanisms and diagnostic challenges","author":"Hemachudha","year":"2002"},{"key":"ref6","first-page":"371","volume-title":"Entry of rabies virus into the peripheral nerves of mice","author":"Watson","year":"1981"},{"key":"ref7","first-page":"2075","volume-title":"The anterograde transport of rabies virus in rat sensory dorsal root ganglia neurons","author":"Tsiang","year":"1989"},{"key":"ref8","first-page":"872","volume-title":"Histopathological alterations in brains of rabies infected buffaloes and cattle","author":"Jamadagni","year":"2007"},{"key":"ref9","volume-title":"","author":"Bennett","year":"2014"},{"key":"ref10","first-page":"91","volume-title":"Regional distribution of rabies viral antigen in central nervous system of human encephalitic and paralytic rabies","author":"Tirawatnpong","year":"1989"},{"key":"ref11","first-page":"1688","volume-title":"Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways","author":"Jamalkandi","year":"2016"},{"key":"ref12","first-page":"498","volume-title":"Human rabies: neuropathogenesis, diagnosis, and management","author":"Hemachudha","year":"2013"},{"key":"ref13","first-page":"319","volume-title":"Pathology of the spinal cord of C57BL\/6J mice infected with rabies virus (CVS-11 strain)","author":"Kojima","year":"2009"},{"key":"ref14","first-page":"79","volume-title":"Rabies virus infection prevents the modulation by \u03b1 2-adrenoceptors, but not muscarinic receptors, of Ca 2+ channels in NG108-15 cells","author":"Iwata","year":"2000"},{"key":"ref15","first-page":"88","volume-title":"The role of immune responses in the pathogenesis of rabies","author":"Hooper","year":"2005"},{"key":"ref16","first-page":"673","volume-title":"Immunologic study of human encephalitic and paralytic rabies: preliminary report of 16 patients","author":"Hemachudha","year":"1988"},{"key":"ref17","first-page":"486","volume-title":"The pathological diagnosis of diffuse gliomas: towards a smart synthesis of microscopic and molecular information in a multidisciplinary context","author":"Wesseling","year":"2011"},{"key":"ref18","first-page":"93","volume-title":"Pathophysiology of human paralytic rabies","author":"Hemachudha","year":"2005"},{"key":"ref19","first-page":"85","volume-title":"Correlation of cytokine expression with rabies virus distribution in rabies encephalitis","author":"Solanki","year":"2009"},{"key":"ref20","first-page":"260","volume-title":"Rabies","author":"Hemachudha","year":"1997"},{"key":"ref21","first-page":"1","volume-title":"Comparative pathogenesis of rabies and rabies-like viruses: infection of the central nervous system and centrifugal spread of virus to peripheral tissues","author":"Murphy","year":"1973"},{"key":"ref22","first-page":"45","volume-title":"Induction of immunoreactive interleukin-1\u03b2 and tumor necrosis factor-\u03b1 in the brains of rabies virus infected rats","author":"Marquette","year":"1996"},{"key":"ref23","first-page":"3024","volume-title":"In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases","author":"Koprowski","year":"1993"},{"key":"ref24","first-page":"357","volume-title":"Microglia, the first line of defence in brain pathologies","author":"Kreutzberg","year":"1995"},{"key":"ref25","first-page":"295","volume-title":"Innate and adaptive immune responses can be beneficial for CNS repair","author":"Schwartz","year":"1999"},{"key":"ref26","first-page":"110","volume-title":"Immune activation in brain aging and neurodegeneration: too much or too little?","author":"Lucin","year":"2009"},{"key":"ref27","first-page":"247","volume-title":"Comparison of immune responses to attenuated rabies virus and street virus in mouse brain","author":"Miao","year":"2017"},{"key":"ref28","first-page":"321","volume-title":"Gymnastics of molecular chaperones","author":"Mayer","year":"2010"},{"key":"ref29","first-page":"670","volume-title":"Hsp70 chaperones: cellular functions and molecular mechanism","author":"Mayer","year":"2005"},{"key":"ref30","first-page":"4743","volume-title":"Hsp70 protein positively regulates rabies virus infection","author":"Lahaye","year":"2012"},{"key":"ref31","first-page":"143","volume-title":"Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression","author":"Ghaemi","year":"2016"},{"key":"ref32","first-page":"1951","volume-title":"Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine","author":"Sajadian","year":"2014"},{"key":"ref33","first-page":"e1000315","volume-title":"Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies","author":"Menager","year":"2009"},{"key":"ref34","first-page":"12893","volume-title":"Virus Infection Switches TLR-3-Positive Human Neurons To Become Strong Producers of Beta-Interferon","author":"Pr\u00e9haud","year":"2005"},{"key":"ref35","first-page":"489","volume-title":"Apoptosis: definition, mechanisms, and relevance to disease","author":"Saikumar","year":"1999"},{"key":"ref36","first-page":"392","volume-title":"Apoptosis as an HIV strategy to escape immune attack","author":"Gougeon","year":"2003"},{"key":"ref37","first-page":"510","volume-title":"Pathogenicity of different rabies virus variants inversely correlates with apoptosis and rabies virus glycoprotein expression in infected primary neuron cultures","author":"Morimoto","year":"1999"},{"key":"ref38","first-page":"101","volume-title":"Neuronal dysfunction and death in rabies virus infection","author":"Fu","year":"2005"},{"key":"ref39","first-page":"299","volume-title":"Caspases: killer proteases","author":"Nicholson","year":"1997"},{"key":"ref40","first-page":"409","volume-title":"Neuronal apoptosis in immunodeficient mice infected with the challenge virus standard strain of rabies virus by intracerebral inoculation","author":"Rutherford","year":"2004"}],"container-title":["Osong Public Health and Research Perspectives"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.kcdcphrp.org\/upload\/phrp-10-1\/ophrp-10-006.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/kcdcphrp.org\/journal\/view.html?doi=10.24171\/j.phrp.2019.10.1.03","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/kcdcphrp.org\/upload\/phrp-10-1\/ophrp-10-006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T23:39:09Z","timestamp":1688600349000},"score":1,"resource":{"primary":{"URL":"https:\/\/ophrp.org\/journal\/view.php?doi=10.24171\/j.phrp.2019.10.1.03"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,28]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"URL":"https:\/\/doi.org\/10.24171\/j.phrp.2019.10.1.03","relation":{},"ISSN":["2210-9099","2233-6052"],"issn-type":[{"value":"2210-9099","type":"print"},{"value":"2233-6052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,28]]},"assertion":[{"value":"2018-09-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-28","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-28","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}