{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:24:56Z","timestamp":1759411496479,"version":"3.37.3"},"reference-count":8,"publisher":"Korea Disease Control and Prevention Agency","issue":"4","license":[{"start":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:00:00Z","timestamp":1628812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ophrp.org"],"crossmark-restriction":true},"short-container-title":["Osong Public Health Res Perspect"],"published-print":{"date-parts":[[2021,8,31]]},"abstract":"<jats:p>Objectives: On February 26, 2021, coronavirus disease 2019 (COVID-19) vaccination was started for high-priority groups based on the recommendation of the Advisory Committee on Immunization Practices with 2 available COVID-19 vaccines (AstraZeneca and Pfizer-BioNTech) in Korea. This report provides a summary of adverse events following COVID-19 vaccination as of April 30, 2021.Methods: Adverse events following immunization are notifiable by medical doctors to the Korea Immunization Management System (KIMS) under the national surveillance system. We analyzed all adverse events reports following COVID-19 vaccination to the KIMS from February 26 to April 30, 2021. Results: In total, 16,196 adverse events following 3,586,814 administered doses of COVID-19 vaccines were reported in approximately 2 months (February 26 to April 30, 2021). Of these, 15,658 (96.7%) were non-serious adverse events, and 538 (3.3%) were serious adverse events, including 73 (0.5%) deaths. The majority of adverse events (n=13,063, 80.7%) were observed in women, and the most frequently reported adverse events were myalgia (52.2%), fever (44.9%), and headache (34.9%). Of the 73 deaths following the COVID-19 vaccination, none were related to the vaccines.Conclusion: By April 30, 3.6 million doses of the COVID 19 vaccine had been given in Korea, and the overwhelming majority of reports were for non-serious events. The Korea Disease Control and Prevention Agency continues to monitor the safety of COVID-19 vaccination.<\/jats:p>","DOI":"10.24171\/j.phrp.2021.0157","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T08:12:06Z","timestamp":1628842326000},"page":"264-268","update-policy":"https:\/\/doi.org\/10.24171\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["COVID-19 vaccine safety monitoring in the Republic of Korea: February 26, 2021 to April 30, 2021"],"prefix":"10.24171","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5741-3250","authenticated-orcid":true,"given":"Hyun-kyung","family":"Oh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5194-0471","authenticated-orcid":true,"given":"Eun Kyeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4015-164X","authenticated-orcid":true,"given":"Insob","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2687-1405","authenticated-orcid":true,"given":"Tae Eun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4411-0941","authenticated-orcid":true,"given":"Yeon-kyeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7244-5314","authenticated-orcid":true,"given":"Eunju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0828-455X","authenticated-orcid":true,"given":"Yeon-Kyeng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31909","reference":[{"volume-title":"","key":"ref1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2021.36.e59"},{"volume-title":"","year":"2020","key":"ref3"},{"volume-title":"","year":"2016","key":"ref4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7008e3"},{"volume-title":"","key":"ref6"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2034577"},{"volume-title":"","year":"2021","key":"ref8"}],"container-title":["Osong Public Health and Research Perspectives"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ophrp.org\/upload\/pdf\/j-phrp-2021-0157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ophrp.org\/journal\/view.php?doi=10.24171\/j.phrp.2021.0157","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ophrp.org\/upload\/pdf\/j-phrp-2021-0157.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T01:48:56Z","timestamp":1629942536000},"score":1,"resource":{"primary":{"URL":"http:\/\/ophrp.org\/journal\/view.php?doi=10.24171\/j.phrp.2021.0157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,31]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"URL":"https:\/\/doi.org\/10.24171\/j.phrp.2021.0157","relation":{},"ISSN":["2210-9099","2233-6052"],"issn-type":[{"type":"print","value":"2210-9099"},{"type":"electronic","value":"2233-6052"}],"subject":[],"published":{"date-parts":[[2021,8,31]]},"assertion":[{"value":"2021-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-13","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}