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The main distribution areas of ZIKV were the African mainland and South-East Asia in the 1980s, Micronesia in 2007, and more recently the Americas in 2014. ZIKV belongs to the Flaviviridae family and Flavivirus genus. ZIKV infection, which is transmitted by Aedes mosquitoes, is an emerging arbovirus disease. The clinical symptoms of ZIKV infection are fever, headache, rashes, arthralgia, and conjunctivitis, which clinically resemble dengue fever syndrome. Sometimes, ZIKV infection has been associated with Guillain-Barr\u00e9 syndrome and microcephaly. At the end of 2015, following an increase in cases of ZIKV infection associated with Guillain-Barr\u00e9 syndrome and microcephaly in newborns in Brazil, the World Health Organization declared a global emergency. Therefore, considering the global distribution and pathogenic nature of this virus, the current study aimed at reviewing the virologic features, transmission patterns, clinical manifestations, diagnosis, treatment, and prevention of ZIKV infection.<\/jats:p>","DOI":"10.24171\/j.phrp.2022.0101","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T01:51:11Z","timestamp":1665539471000},"page":"341-351","update-policy":"https:\/\/doi.org\/10.24171\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Zika virus as an emerging arbovirus of international public health concern"],"prefix":"10.24171","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7227-7899","authenticated-orcid":true,"given":"Samira","family":"Vaziri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1690-5133","authenticated-orcid":true,"given":"Siavash 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