{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:15:53Z","timestamp":1787786153457,"version":"build-2784847793"},"reference-count":16,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2000,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To quantify and compare intracellular\nmagnesium concentrations (Mg<jats:sub>i<\/jats:sub>) in clinically normal\ndogs (control dogs) and dogs that have gastric dilatation-\nvolvulus (GDV dogs) and to determine whether\nthere is a difference in Mg<jats:sub>i<\/jats:sub> and serum magnesium\nconcentrations (Mg<jats:sub>s<\/jats:sub>) between GDV dogs with and\nwithout cardiac arrhythmias.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201441 control dogs and 21 GDV dogs.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Rectus abdominis muscle specimens\nwere obtained from control and GDV dogs for determination\nof Mg<jats:sub>i<\/jats:sub>. Blood samples were obtained from\nGDV dogs for determination of Mg<jats:sub>s<\/jats:sub>, and dogs were\nmonitored for 48 hours for cardiac arrhythmias.\nMuscle specimens were frozen at \u201340 C, oven dried\nat 95 C, and digested with concentrated nitric acid.\nMultielemental analyses were performed by simultaneous\/\nsequential inductively coupled plasma-atomic\nemission spectroscopy with fixed-cross flow nebulization.\nThe Mg<jats:sub>i<\/jats:sub> was standardized to sulfur content to\ncorrect for the amount of fat and fascia in the muscle\nspecimen. Mean (\u00b1 SEM) values were recorded in\nparts per million (ppm).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014There were no significant differences in\nMg<jats:sub>i<\/jats:sub> between control (627 \u00b1 11.1 ppm) and GDV (597\n\u00b1 20.5 ppm) dogs, in Mg<jats:sub>i<\/jats:sub> between GDV dogs with\n(590 \u00b1 34 ppm) and without (584 \u00b1 29 ppm) cardiac\narrhythmias, and in Mg<jats:sub>s<\/jats:sub> between GDV dogs with\n(1.77 \u00b1 0.26 ppm) and without (1.51 \u00b1 0.09 ppm) cardiac\narrhythmias. There was no correlation between\nMg<jats:sub>s<\/jats:sub> and Mg<jats:sub>i<\/jats:sub> ( <jats:italic>R<jats:sup>2<\/jats:sup>\n\t\t\t\t\t<\/jats:italic>=0.0001).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results indicate\nthat Mg depletion is not pathophysiologically\nimportant in dogs with GDV and does not play a role\nin the cardiac arrhythmias detected in these patients.\n(<jats:italic>Am J Vet Res<\/jats:italic> 2000;61:1415\u20131417)<\/jats:p>","DOI":"10.2460\/ajvr.2000.61.1415","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T17:12:54Z","timestamp":1133889174000},"page":"1415-1417","source":"Crossref","is-referenced-by-count":18,"title":["Intracellular magnesium concentrations in dogs with gastric dilatation-volvulus"],"prefix":"10.2460","volume":"61","author":[{"given":"Trevor N.","family":"Bebchuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe G.","family":"Hauptman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Emmett","family":"Braselton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Walshaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"p_1_383","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.2460\/javma.1996.208.11.1855","volume":"208","author":"Brourman JD","year":"1996","journal-title":"J Am Vet Med Assoc"},{"key":"p_2_384","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.2460\/javma.1994.204.09.1465","volume":"204","author":"Glickman LT","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"p_3_385","first-page":"363","volume":"181","author":"Muir WW","year":"1982","journal-title":"J Am Vet Med Assoc"},{"key":"p_4_386","first-page":"683","volume":"172","author":"Muir WW III","year":"1978","journal-title":"J Am Vet Med Assoc"},{"key":"p_5_387","first-page":"186","volume":"2","author":"Olerich MA","year":"1994","journal-title":"New Horiz"},{"key":"p_6_388","first-page":"128","author":"Martin LG","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_7_389","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00003246-198808000-00004","volume":"16","author":"Fiaccadori E","year":"1988","journal-title":"Crit Care Med"},{"key":"p_8_390","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1365-2044.1995.tb04556.x","volume":"50","author":"Arnold A","year":"1995","journal-title":"Anaesthesia"},{"key":"p_9_391","first-page":"41","volume":"19","author":"Macintire DK","year":"1997","journal-title":"Compend Contin Educ Pract Vet"},{"key":"p_10_392","first-page":"70","volume":"85","author":"Gettes LS","year":"1992","journal-title":"Circulation"},{"key":"p_11_393","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1177\/104063879700900409","volume":"9","author":"Braselton WE","year":"1997","journal-title":"J Vet Diagn Invest"},{"key":"p_12_394","first-page":"561","volume":"46","author":"Stowe HD","year":"1985","journal-title":"Am J Vet Res"},{"key":"p_13_395","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1126\/science.7361117","volume":"208","author":"Turlapaty PD","year":"1980","journal-title":"Science"},{"key":"p_14_396","first-page":"721","volume":"112","author":"Wong NML","year":"1988","journal-title":"J Lab Clin Med"},{"key":"p_15_397","first-page":"115","volume":"1","author":"Elin RJ","year":"1982","journal-title":"Magnesium"},{"key":"p_16_398","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1161\/01.CIR.92.8.2190","volume":"92","author":"Haigney MCP","year":"1995","journal-title":"Circulation"}],"container-title":["American Journal of Veterinary Research"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/61\/11\/ajvr.2000.61.1415.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/61\/11\/ajvr.2000.61.1415.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/61\/11\/ajvr.2000.61.1415.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T12:44:06Z","timestamp":1741351446000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/61\/11\/ajvr.2000.61.1415.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11,1]]},"references-count":16,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.2460\/ajvr.2000.61.1415","relation":{},"ISSN":["0002-9645"],"issn-type":[{"value":"0002-9645","type":"print"}],"subject":[],"published":{"date-parts":[[2000,11,1]]}}}