{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:58:27Z","timestamp":1784131107885,"version":"3.55.0"},"reference-count":24,"publisher":"American Veterinary Medical Association (AVMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2001,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To assess selenium (Se) status of cats in\n4 regions of the world and to compare results for Se\nstatus with reported incidence of hyperthyroidism in\ncats in those regions.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201450 cats (30 from 2 regions with an allegedly\nhigh incidence of hyperthyroidism and 20 from 2 regions\nin which the disease is less commonly reported).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Hematologic samples (heparinized\nwhole blood, plasma, and RBC fractions) were\nobtained from 43 healthy euthyroid cats and 7 hyperthyroid\ncats. Plasma concentration of Se and activity\nof glutathione peroxidase (GPX) in whole blood and\nplasma were determined.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Plasma concentration of Se and GPX activity\nin whole blood or plasma did not differ significantly\namong cats from the 4 regions. However, cats had\na plasma concentration of Se that was approximately\n10 times the concentration reported in rats and\nhumans. The GPX activity in whole blood or plasma in\ncats generally was higher than values reported in rats\nor humans.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Cats have\nhigher Se concentrations in plasma, compared with\nvalues for other species. However, Se status alone\ndoes not appear to affect the incidence of hyperthyroidism\nin cats. High Se concentrations may have\nimplications for health of cats if such concentrations\nare influenced by the amount of that micronutrient\nincluded in diets. (<jats:italic>Am J Vet Res<\/jats:italic> 2001;62:934\u2013937)<\/jats:p>","DOI":"10.2460\/ajvr.2001.62.934","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T17:31:35Z","timestamp":1133890295000},"page":"934-937","source":"Crossref","is-referenced-by-count":17,"title":["Selenium status of cats in four regions of the world and comparison with reported incidence of hyperthyroidism in cats in those regions"],"prefix":"10.2460","volume":"62","author":[{"given":"Darren J.","family":"Foster","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith L.","family":"Thoday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Arthur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fergus","family":"Nicol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia A.","family":"Beatty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl K.","family":"Svendsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Labuc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"McConnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Sharp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan B.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffery J.","family":"Beckett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"p_1_644","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF02917202","volume":"24","author":"Aaeseth J","year":"1990","journal-title":"Biol Trace Elem Res"},{"key":"p_2_645","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.6.2052"},{"key":"p_3_646","first-page":"123","volume":"7","author":"Beckett GJ","year":"1993","journal-title":"J Trace Elem Electrolytes Health Dis"},{"key":"p_4_647","doi-asserted-by":"publisher","DOI":"10.1039\/an9952000827"},{"key":"p_5_648","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1042\/bj3080713","volume":"308","author":"Howie AF","year":"1995","journal-title":"Biochem J"},{"key":"p_6_649","first-page":"265","volume":"5","author":"Beckett GJ","year":"1991","journal-title":"J Trace Elem Electrolytes Health Dis"},{"key":"p_7_650","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/vr.131.12.257","volume":"131","author":"Thoday KL","year":"1992","journal-title":"Vet Rec"},{"key":"p_8_651","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5877(88)90041-4"},{"key":"p_9_652","first-page":"133","author":"Ferguson DC","year":"1994","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_10_653","first-page":"303","volume":"9","author":"Powis G","year":"1997","journal-title":"Oncol Res"},{"key":"p_11_654","doi-asserted-by":"publisher","DOI":"10.1892\/0891-6640(1999)013<0323:EOENAH>2.3.CO;2"},{"key":"p_12_655","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1748-5827.1999.tb03087.x","volume":"40","author":"Foster DJ","year":"1999","journal-title":"J Small Anim Pract"},{"key":"p_13_656","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/jn\/118.6.747","volume":"118","author":"Arthur JR","year":"1988","journal-title":"J Nutr"},{"key":"p_14_657","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1042\/bj2480539","volume":"248","author":"Arthur JR","year":"1987","journal-title":"Biochem J"},{"key":"p_15_658","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/thy.1992.2.125","volume":"2","author":"Brown RS","year":"1992","journal-title":"Thyroid"},{"key":"p_16_659","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1042\/bj2480443","volume":"248","author":"Beckett GJ","year":"1987","journal-title":"Biochem J"},{"key":"p_17_660","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1042\/bj2820483","volume":"282","author":"Beckett GJ","year":"1992","journal-title":"Biochem J"},{"key":"p_18_661","first-page":"524","author":"Bellisola G","year":"1998","journal-title":"Paris: John Libbey Eurotext"},{"key":"p_19_662","first-page":"297","volume":"50","author":"Koller LD","year":"1986","journal-title":"Can J Vet Res"},{"key":"p_20_663","doi-asserted-by":"publisher","DOI":"10.1016\/0162-0134(90)80018-S"},{"key":"p_21_664","doi-asserted-by":"publisher","DOI":"10.1108\/00346659510093991"},{"key":"p_22_665","first-page":"242","author":"Neve J","year":"1998","journal-title":"Paris: John Libbey Eurotext"},{"key":"p_23_666","first-page":"1633","volume":"47","author":"Mumma RO","year":"1986","journal-title":"Am J Vet Res"},{"key":"p_24_667","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1080\/00480169.1992.35691","volume":"40","author":"Johnson LA","year":"1992","journal-title":"N Z Vet J"}],"container-title":["American Journal of Veterinary Research"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/62\/6\/ajvr.2001.62.934.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/62\/6\/ajvr.2001.62.934.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/62\/6\/ajvr.2001.62.934.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T12:54:28Z","timestamp":1741352068000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/62\/6\/ajvr.2001.62.934.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6,1]]},"references-count":24,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2460\/ajvr.2001.62.934","relation":{},"ISSN":["0002-9645"],"issn-type":[{"value":"0002-9645","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6,1]]}}}