{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T21:10:04Z","timestamp":1775769004274,"version":"3.50.1"},"reference-count":39,"publisher":"American Veterinary Medical Association (AVMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2005,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To evaluate the respiratory excretion and\nelimination kinetics of organic and inorganic selenium\nafter oral administration in sheep.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals<\/jats:bold>\n                    \u201438 crossbred sheep.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedures<\/jats:bold>\n                    \u2014Selenium was administered PO to\nsheep as a single dose of 0, 1, 2, 3, or 4 mg\/kg as\nsodium selenite or selenomethionine. Expired air was\ncollected and analyzed from all sheep at 4, 8, and 16\nhours after administration.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u2014Clinical signs consistent with selenium\nintoxication were seen in treatment groups given\nsodium selenite but not in treatment groups given\nthe equivalent amount of selenium as selenomethionine.\nHowever, a distinct garlic-like odor was\nevident in the breath of all sheep receiving 2 to 4\nmg of selenium\/kg. The intensity of odor in the\nbreath did not correlate with clinical signs in\naffected animals receiving sodium selenite treatment.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014The concentration\nof selenium in expired air was greater in\nsheep receiving selenium as selenomethionine than\nsodium selenite. The concentration of selenium in\nexpired air from sheep receiving high doses of selenium\n(3 and 4 mg of selenium\/kg) was larger and\nselenium was expired for a longer duration than the\nconcentration of selenium in expired air from sheep\nreceiving low doses of selenium (1 and 2 mg of selenium\/kg). 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