{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:16:17Z","timestamp":1778109377196,"version":"3.51.4"},"reference-count":34,"publisher":"American Veterinary Medical Association (AVMA)","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"Abstract<\/jats:title>\n\nOBJECTIVE<\/jats:title>\nTo evaluate the effects of combining one-lung ventilation and carbon dioxide insufflation (OLV-CDI) on intrathoracic working space (determined by means of CT) during thoracoscopy in dogs and investigate conditions that could safely improve working space compared with OLV alone.<\/jats:p>\n<\/jats:sec>\n\nANIMALS<\/jats:title>\n6 healthy Beagles.<\/jats:p>\n<\/jats:sec>\n\nPROCEDURES<\/jats:title>\nDogs were anesthetized, and right- or left-sided (n = 3\/side) OLV was instituted. On the blocked side, a laparoscopic trocar sleeve was placed in the ninth intercostal space for CDI. CT was performed under 3 conditions: with OLV alone, with OLV-CDI at an intrapleural pressure (IPP) of 3 mm Hg, and with OLV-CDI at an IPP of 5 mm Hg. Working space volume (WSV), ventilation space volume (VSV), and thoracic cavity volume (TCV) were determined from CT images.<\/jats:p>\n<\/jats:sec>\n\nRESULTS<\/jats:title>\nWith OLV-CDI at an IPP of 3 or 5 mm Hg, WSV and TCV were significantly increased, compared with values obtained during OLV alone. With OLV-CDI at an IPP of 5 mm Hg, VSV and Spo<\/jats:sc>2<\/jats:sub> were significantly decreased, compared with values obtained during OLV alone. Additionally, contralateral pneumothorax was observed in 4 dogs at an IPP of 5 mm Hg.<\/jats:p>\n<\/jats:sec>\n\nCLINICAL RELEVANCE<\/jats:title>\nCombining OLV and CDI could provide a larger working space than OLV alone, even with an IPP of 3 mm Hg, in dogs of limited size. However, an evaluation of the effects on oxygenation and cardiovascular variables is needed before clinical use.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.22.01.0009","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T12:43:52Z","timestamp":1658753032000},"source":"Crossref","is-referenced-by-count":7,"title":["Effects of combined one-lung ventilation and intrathoracic carbon dioxide insufflation on intrathoracic working space when performing thoracoscopy in dogs"],"prefix":"10.2460","volume":"83","author":[{"given":"Eiichi","family":"Kanai","sequence":"first","affiliation":[{"name":"Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Matsutani","sequence":"additional","affiliation":[{"name":"Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan"},{"name":"Teikyo University Hospital Mizonokuchi, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Universit\u00e9 de Montr\u00e9al, Saint-Hyacinthe, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuto","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, School of Medicine, Teikyo University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Sakai","sequence":"additional","affiliation":[{"name":"Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Misumi","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Medicine, Yokohama City University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Fujii","sequence":"additional","affiliation":[{"name":"Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Takagi","sequence":"additional","affiliation":[{"name":"Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"5","key":"B1","series-title":"Can Vet J","first-page":"285","article-title":"Examination of the thoracic cavity and lung lobectomy by means of thoracoscopy in dogs","volume":"39","year":"1998","unstructured":"Garc\u00eda F, Prandi D, Pe\u00f1a T, Franch J, Trasserra O, de la Fuente J. 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