{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:54:34Z","timestamp":1767192874643},"reference-count":35,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To assess the histological injury and intestinal microperfusion measured by laser Doppler flowmetry and spectrophotometry (LDFS) of the small intestine orad to a strangulation during colic surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>Horses with naturally occurring small intestinal strangulations undergoing colic surgery were included.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>METHODS<\/jats:title>\n<jats:p>In this prospective clinical trial, intestinal tissue oxygen saturation (tSO<jats:sub>2<\/jats:sub>) and tissue blood flow (tBF) were measured by LDFS orad to the strangulation following release of the strangulation (n = 18). The number of horses with postoperative reflux (POR) and the cases that survived until discharge were compared between groups using Fisher\u2019s exact test (<jats:italic>P<\/jats:italic> &lt; .05). Intestinal biopsies were taken in cases that underwent intestinal resection or intraoperative euthanasia (n = 28). Measurements were compared between injured and noninjured segments with a Mann-Whitney <jats:italic>U<\/jats:italic> or <jats:italic>t<\/jats:italic> test.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The tSO<jats:sub>2<\/jats:sub> and tBF of the orad intestine were lower than previously reported in healthy horses. Horses with low tSO<jats:sub>2<\/jats:sub> of &lt; 35% were significantly more likely to suffer from POR (6\/6 cases) compared to cases with tSO<jats:sub>2<\/jats:sub> &gt; 69% (1\/6). The number of horses that survived were not statistically different between these groups (2\/6 and 6\/6). All horses with mucosal injury developed POR (6\/6), which was significantly more likely compared to horses without mucosal injury (3\/13). No significant difference in tSO<jats:sub>2<\/jats:sub> or tBF could be found between the segments with and without histological injury.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>The results suggest that measuring tSO<jats:sub>2<\/jats:sub> in the orad segment during colic surgery may aid in predicting postoperative issues.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.23.12.0286","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T15:17:21Z","timestamp":1713280641000},"source":"Crossref","is-referenced-by-count":4,"title":["Measuring tissue oxygen saturation in the orad intestinal segment during equine colic surgery may aid in predicting the occurrence of postoperative ileus"],"prefix":"10.2460","volume":"85","author":[{"given":"Nicole","family":"Verhaar","sequence":"first","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Marei","family":"Grages","sequence":"additional","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fay J.","family":"Sauer","sequence":"additional","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Geiger","sequence":"additional","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wencke","family":"Reineking","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Hewicker-Trautwein","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Geburek","sequence":"additional","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine B.R.","family":"K\u00e4stner","sequence":"additional","affiliation":[{"name":"Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany"},{"name":"Clinic for Small Animals, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"4","key":"B1","series-title":"Equine Vet J","first-page":"331","article-title":"The characteristics of intestinal injury peripheral to strangulating obstruction lesions in the equine small intestine","volume":"31","author":"Gerard M","year":"1999","unstructured":"Gerard M, Blikslager A, Roberts M, Tate LP Jr, Argenzio RA. 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