{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T13:43:30Z","timestamp":1774446210888,"version":"3.50.1"},"reference-count":31,"publisher":"American Veterinary Medical Association (AVMA)","issue":"8","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To describe the CT findings of Australian dogs and cats with nasal cryptococcosis over a 12-year period.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>12 dogs and 9 cats diagnosed with nasal cryptococcosis from 2008 through 2020.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>METHODS<\/jats:title>\n<jats:p>CT findings were compared among enrolled cases from Australian veterinary referral centers. Disease severity was compared between a subset of patients with cryptococcal speciation performed (n = 6 dogs; n = 3 cats) and geographic domicile.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Dogs demonstrated diffuse disease affecting numerous nasal regions and sinuses. Cats displayed more focal nasal and nasopharyngeal disease. Dogs were more likely to have a nasal mass, whereas cats were more likely to have a nasopharyngeal mass. Cribriform plate lysis was common in dogs but not observed in cats. Sinonasal osteolysis was a common feature in both species. Mandibular lymph nodes were commonly enlarged in dogs, whereas in cats, the retropharyngeal lymph nodes were more likely enlarged. There was no obvious difference in disease severity or lesion distribution in relation to the causal species of <jats:italic>Cryptococcus<\/jats:italic>, although to determine if this finding is robust, an appropriately powered prospective study is warranted.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>There are numerous studies describing the clinical features, treatment, and outcomes of dogs and cats with cryptococcosis. To the best of our knowledge, there is only 1 previous study describing the CT features of nasal cryptococcosis, undertaken in one part of North America. Our study describes the CT features of nasal <jats:italic>Cryptococcus<\/jats:italic> sp in an Australian canine and feline cohort, adding new pertinent observations while reinforcing reported radiological observations.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.24.03.0054","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T12:34:02Z","timestamp":1717158842000},"source":"Crossref","is-referenced-by-count":1,"title":["Computed tomography findings of nasal cryptococcosis in Australia (2008\u20132020): 12 dogs and 9 cats"],"prefix":"10.2460","volume":"85","author":[{"given":"Samantha A.","family":"Wong","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Veterinary Specialist Services, Underwood, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Else","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Veterinary Specialist Services, Underwood, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Podadera","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Veterinary Teaching Hospital Sydney, School of Veterinary Science, The University of Sydney, Camperdown, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia Wen","family":"Siow","sequence":"additional","affiliation":[{"name":"Department of Radiology, Small Animal Specialist Hospital, Kent Town, SA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis J.","family":"Woerde","sequence":"additional","affiliation":[{"name":"William R Pritchard Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Tebb","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Western Australian Veterinary Emergency & Specialty, Success, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Veterinary Teaching Hospital Sydney, School of Veterinary Science, The University of Sydney, Camperdown, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dave","family":"Colins","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Northside Veterinary Specialists, Terrey Hills, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Lunn","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Queensland Vets \u2013 Small Animal Hospital, Gatton, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Malik","sequence":"additional","affiliation":[{"name":"Center for Veterinary Education, Sydney School of Veterinary Science, Veterinary Science Conference Center, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"2","key":"B1","series-title":"Med Mycol","first-page":"133","article-title":"Cryptococcosis in cats: clinical and mycological assessment of 29 cases and evaluation of treatment using orally administered fluconazole","volume":"30","author":"Malik R","year":"1992","unstructured":"Malik R, Wigney DI, Muir DB, Gregory DJ, Love DN. 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