{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T19:04:50Z","timestamp":1789844690935,"version":"4.0.1"},"reference-count":37,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2025,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>A comprehensive research was conducted to investigate the incidence of avian pathogenic <jats:italic>Escherichia coli<\/jats:italic> (APEC) in ostrich farms in Egypt.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>METHODS<\/jats:title>\n<jats:p>The study involved seven farms with bird ages ranging from 1 to 12 weeks and capacities of 2,000 to 5,000 birds per farm. 175 tissue specimens were collected from different organs (liver, spleen, heart, lung, kidney, intestine, and meat).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Clinical signs of APEC infection included diarrhea, lethargy, depression, and weight loss, with a morbidity rate of 36% and a mortality rate of 7.6%. In the current study, 52.5% of the samples have <jats:italic>E coli<\/jats:italic>. The highest prevalence was observed in the liver (10.8%), followed by the spleen and intestine (8% and 9.1%, respectively). The most common serotype identified was O27 (28%), after that O78 (20%) and O44 (12%). Histopathological examination revealed severe lesions in various organs, including the liver, kidney, heart, and intestine.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>The study concluded the presence of APEC in different organs of ostrich in Egypt especially the liver, spleen, intestine, and breast muscle (meat) with evidence of severe pathological lesions in various organs.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>The study highlights the significance of APEC as a main cause of morbidity and mortality in ostriches. It underscores the necessity for actual control measures to avoid spreading the disease.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.24.09.0280","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T13:19:41Z","timestamp":1734527981000},"source":"Crossref","is-referenced-by-count":8,"title":["Avian pathogenic Escherichia coli and ostriches: a deep dive into pathological and microbiological investigation"],"prefix":"10.2460","volume":"86","author":[{"given":"Rania S.","family":"Zaki","sequence":"first","affiliation":[{"name":"Department of Food Hygiene, Safety and Technology, Faculty of Veterinary Medicine, New Valley University, El Kharga, Egypt"},{"name":"Department of Food Science, Purdue University, West Lafayette, IN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nady Kh.","family":"Elbarbary","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene, Faculty of Veterinary Medicine, Aswan University, Aswan, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal A.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Animal Hygiene and Environmental Sanitation, Assiut, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounir M.","family":"Bekhit","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed M.","family":"Salem","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"Darweish","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, Qaluiobia, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Fotouh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, New Valley University, El Kharga, Egypt"},{"name":"Department of Business Administration, MBA Program, Marywood University, Scranton, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"3","key":"B1","series-title":"Human Vet Med","first-page":"71","article-title":"Zoonotic potential of salmonella and Escherichia coli isolated from ostrich eggs of a flock in a recreational park","volume":"9","author":"Youssef AI","year":"2017","unstructured":"Youssef AI, Afifi RA. 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