{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T04:08:23Z","timestamp":1746158903664,"version":"3.40.4"},"reference-count":29,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To investigate the effects of propofol and sevoflurane anesthesia on the oxidant-antioxidant status and biochemical parameters in Turkish hair goats.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The study was conducted from February 15 through March 15, 2024. Seven clinically healthy female Turkish hair goats aged 1 to 2 years with an average live weight of 29.95 (26.1 to 33.8) kg were included. A bolus of propofol (6 mg\/kg) was injected IV. The goats were placed in the sternoabdominal position and administered 1% to 3% sevoflurane with 100% oxygen for 2 hours with the help of a vaporizer. Blood samples were collected before and after the administration of propofol and at the 15th, 30th, 60th, and 120th minutes after the start of sevoflurane administration in nonanticoagulated tubes. The oxidant-antioxidant status (serum total antioxidant status, total oxidant status, paraoxonase activity, and arylesterase activity) and biochemical parameters (levels of glucose, AST, GGT, ALT, ALP, LDH, creatine kinase, amylase, lipase, creatinine, urea, uric acid, high-density lipoprotein, low-density lipoprotein, total protein, albumin, total bilirubin, direct bilirubin, magnesium, chlorine, calcium, iron, sodium, phosphorus, and potassium) were evaluated. The heart rate, respiratory rate, and body temperature of the goats were measured using a bedside monitor.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>Results<\/jats:title>\n<jats:p>Arylesterase activity increased with sevoflurane administration. Changes were observed in heart rate and body temperature as well as in the levels of glucose, creatine kinase, urea, total bilirubin, and potassium at different time intervals of propofol-sevoflurane administration.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Propofol-sevoflurane anesthesia has no adverse effects on oxidant-antioxidant status in Turkish hair goats.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>Clinical Relevance<\/jats:title>\n<jats:p>The evaluation of heart rate and body temperature, as well as glucose, creatine kinase, urea, total bilirubin, and potassium levels, must be considered in propofol-sevoflurane anesthesia protocol.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.24.10.0309","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T13:19:53Z","timestamp":1739884793000},"source":"Crossref","is-referenced-by-count":0,"title":["Investigation of the effects of propofol and sevoflurane anesthesia on oxidant-antioxidant status and biochemical parameters in Turkish hair goats"],"prefix":"10.2460","volume":"86","author":[{"given":"Ali","family":"G\u00fclayd\u0131n","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u0131van\u00e7","family":"\u0130rak","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihat","family":"\u015e\u0131ndak","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa Bar\u0131\u015f","family":"Akg\u00fcl","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zg\u00fcr Ya\u015far","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onur","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maruf","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erman","family":"G\u00fclenda\u011f","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Veterinary Medicine, Siirt University, Siirt, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"B1","series-title":"Turk Klin Vet Sci Surg Spec Top","first-page":"24","article-title":"Anesthesia protocol in neonatal calves: anesthesia applications in surgical cases in calves","volume":"5","author":"Alkan \u0130","year":"2019","unstructured":"Alkan \u0130, Atasoy N, Ta\u015f A, et al. 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