{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:04:35Z","timestamp":1792595075478,"version":"4.5.0"},"reference-count":26,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To evaluate the impact of intrahepatic portal vein branching (IHPB)-grade assessment using preoperative CT angiography (CTA) on the surgical procedure and prognosis prediction for dogs with an extrahepatic portosystemic shunt (EHPSS).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This study involved 146 client-owned dogs with EHPSS. The shunt morphology of EHPSS and IHPB grades was determined using CTA. All dogs underwent surgical attenuation of the shunt with intraoperative portal vein pressure (PVP) measurement, followed by a liver biopsy of the left lateral lobe. The preoperative CTA findings were analyzed according to surgical procedures, intraoperative PVP, hepatic histopathology, and postoperative complications.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>Results<\/jats:title>\n<jats:p>The grade of IHPB did not correlate with baseline PVP while it significantly correlated with PVP during temporary occlusion and the difference in PVP between before and during the temporary occlusion. The grade of IHPB and PVP had significant differences between the dogs with partial ligation compared with those with complete ligation. The portal vein hypoplasia score on histopathology was generally higher in the dogs with low-grade IHPB than in those with high-grade IHPB. The IHPB grade had no significant influence on postoperative complications and prognosis.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>This study demonstrated that although the grade assessment system of IHPB using preoperative CTA was unable to predict the prognosis of dogs with a single EHPSS, it may be useful for determining surgical procedure selection.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>Clinical Relevance<\/jats:title>\n<jats:p>Preoperative CTA is suggested to not only be useful for the diagnosis and classification of EHPSS but also for surgical planning of EHPSS in dogs.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.24.11.0333","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T14:36:40Z","timestamp":1737470200000},"source":"Crossref","is-referenced-by-count":2,"title":["Use of computed tomography angiography has potential in planning surgical treatment of an extrahepatic portosystemic shunt in dogs"],"prefix":"10.2460","volume":"86","author":[{"given":"Ryo","family":"Takeuchi","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumiko","family":"Ishigaki","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaito","family":"Iida","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieko","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Shiozawa","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Yamaoka","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0099-7974","authenticated-orcid":true,"given":"Kazushi","family":"Asano","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"2","key":"B1","series-title":"Vet Sci","first-page":"160","article-title":"Congenital portosystemic shunts in dogs and cats: classification, pathophysiology, clinical presentation and diagnosis","volume":"10","author":"Konstantinidis AO","year":"2023","unstructured":"Konstantinidis AO, Patsikas MN, Papazoglou LG, Adamama-Moraitou KK. Congenital portosystemic shunts in dogs and cats: classification, pathophysiology, clinical presentation and diagnosis. Vet Sci. 2023;10(2):160. doi:10.3390\/vetsci10020160"},{"issue":"5","key":"B2","series-title":"J Am Vet Med Assoc","first-page":"527","article-title":"Long-term survival and quality of life in dogs with clinical signs associated with a congenital portosystemic shunt after surgical or medical treatment","volume":"245","author":"Greenhalgh SN","year":"2014","unstructured":"Greenhalgh SN, Reeve JA, Johnstone T, et al. Long-term survival and quality of life in dogs with clinical signs associated with a congenital portosystemic shunt after surgical or medical treatment. J Am Vet Med Assoc. 2014;245(5):527\u2013533. doi:10.2460\/javma.245.5.527"},{"issue":"5","key":"B3","series-title":"Vet Sci","first-page":"346","article-title":"Congenital portosystemic shunts in dogs and cats: treatment, complications and prognosis","volume":"10","author":"Konstantinidis AO","year":"2023","unstructured":"Konstantinidis AO, Adamama-Moraitou KK, Patsikas MN, Papazoglou LG. Congenital portosystemic shunts in dogs and cats: treatment, complications and prognosis. Vet Sci. 2023;10(5):346. doi:10.3390\/vetsci10050346"},{"issue":"5","key":"B4","series-title":"J Vet Intern Med","first-page":"1865","article-title":"Treatment of congenital extrahepatic portosystemic shunts in dogs: a systematic review and meta-analysis","volume":"33","author":"Serrano G","year":"2019","unstructured":"Serrano G, Charalambous M, Devriendt N, de Rooster H, Mortier F, Paepe D. Treatment of congenital extrahepatic portosystemic shunts in dogs: a systematic review and meta-analysis. 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