{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T15:40:35Z","timestamp":1743522035214,"version":"3.40.3"},"reference-count":51,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"sc_a1\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To compare the biomechanical properties of standard-of-care limb salvage stainless steel plates with metal endoprosthesis constructs to constructs without endoprosthesis.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a2\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This was a cadaveric biomechanical study including 5 pairs of normal canine thoracic limbs randomly allocated into 2 groups: limbs with a second-generation, 11.5-mm Veterinary Orthopedic Implants stainless steel plate and a 122-mm stainless steel with endoprosthesis (SS-E) and limbs without endoprostheses or stainless steel with a gap (SS-G). Standard limb-spare surgery was performed and reconstructed with or without endoprostheses (ie, gap). Limbs were tested in axial loading until failure, and load-deformation curves were used to determine the biomechanical properties of the constructs, compared using a Wilcoxon matched-pairs signed-rank test. Failure modes were compared descriptively.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a3\">\n<jats:title>Results<\/jats:title>\n<jats:p>Yield load (644 \u00b1 523 N and 288 \u00b1 153 N), yield energy absorbed (1,126 \u00b1 1,695 N\/mm and 239 \u00b1 251 N\/mm), and ultimate energy absorbed (39,732 \u00b1 11,679 N\/mm and 5,175 \u00b1 878 N\/mm) were significantly different between the SS-E and SS-G groups, respectively. Stiffness (360 \u00b1 64 N\/mm and 180 \u00b1 50 N\/mm) and ultimate load (3,385 \u00b1 512 N and 747 \u00b1 98 N) were not. The mode of failure varied between groups, with 2 SS-E constructs failing by humeral fracture and 3 by plate bending at the most distal radial or radiocarpal screw holes, whereas all SS-G constructs failed by plate bending midgap.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a4\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Limbs incorporating endoprosthesis were biomechanically superior to limbs reconstructed with a gap.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sc_a5\">\n<jats:title>Clinical Relevance<\/jats:title>\n<jats:p>Limbs reconstructed with locking 11.5-mm Veterinary Orthopedic Implants plates without endoprosthesis may fail at physiological forces during trot or run.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.24.11.0364","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T20:38:37Z","timestamp":1738874317000},"source":"Crossref","is-referenced-by-count":0,"title":["Biomechanical comparison of standard-of-care endoprosthesis limb-sparing technique to a gap group with stainless steel plates and no endoprostheses in the distal radial site of dogs"],"prefix":"10.2460","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3880-4875","authenticated-orcid":true,"given":"Josep","family":"Aisa","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida Gainesville, FL"},{"name":"Flint Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7465-3854","authenticated-orcid":true,"given":"James W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Walter Scott Jr College of Engineering, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8458-1735","authenticated-orcid":true,"given":"Brandan G.","family":"Wustefeld-Janssens","sequence":"additional","affiliation":[{"name":"Flint Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"B1","series-title":"Withrow and MacEwen's Small Animal Clinical Oncology","first-page":"524","article-title":"Tumors of the skeletal system","author":"Ehrhart NP","year":"2020","unstructured":"Ehrhart NP, Christensen NI, Fan TM. 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