{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T12:10:01Z","timestamp":1751544601817,"version":"3.41.0"},"reference-count":8,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>We evaluated bovine respiratory disease vaccine trials in feedlot cattle and found that most (19 of 34 [56%]) publications (describing 26 of 43 [60%] trials) labeled the control group as \u201cunvaccinated\u201d or similar terms even when all cattle in the trial received vaccine(s) at feedlot arrival. Additionally, 38 of 44 (86%) publications (describing 31 of 53 [58%] trials) reported statistical comparisons of bovine respiratory disease vaccines that did not mention the respiratory vaccines that all cattle received at feedlot arrival. Trial authors should report animal health products given to all cattle in a trial, in the abstract, methods, and results sections, to prevent misinterpretation of the actual comparisons investigated.<\/jats:p>","DOI":"10.2460\/ajvr.24.12.0389","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T13:00:58Z","timestamp":1743685258000},"source":"Crossref","is-referenced-by-count":0,"title":["Incomplete reporting in randomized controlled trials of bovine respiratory disease vaccines in feedlot cattle"],"prefix":"10.2460","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2624-9405","authenticated-orcid":true,"given":"Sarah C.","family":"Totton","sequence":"first","affiliation":[{"name":"Independent Contractor, Guelph, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan M.","family":"Sargeant","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0604-7822","authenticated-orcid":true,"given":"Annette M.","family":"O\u2019Connor","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"year":"2001","unstructured":"International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. Guidance for industry: E10 choice of control group and related issues in clinical trials. Docket No. FDA-1999-D-1874. Food and Drug Administration. May 2001. Accessed February 22, 2025. https:\/\/www.fda.gov\/media\/71349\/download","key":"B1"},{"issue":"2","key":"B2","series-title":"Anim Health Res Rev","first-page":"143","article-title":"A systematic review and network meta-analysis of bacterial and viral vaccines, administered at or near arrival at the feedlot, for control of bovine respiratory disease in beef cattle","volume":"20","author":"O\u2019Connor AM","year":"2019","unstructured":"O\u2019Connor AM, Hu D, Totton SC, et al. A systematic review and network meta-analysis of bacterial and viral vaccines, administered at or near arrival at the feedlot, for control of bovine respiratory disease in beef cattle. Anim Health Res Rev. 2019;20(2):143\u2013162. doi:10.1017\/S1466252319000288"},{"issue":"1","key":"B3","series-title":"Can Vet J","first-page":"43","article-title":"Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves","volume":"44","author":"Schunicht OC","year":"2003","unstructured":"Schunicht OC, Booker CW, Jim GK, Guichon PT, Wildman BK, Hill BW. Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves. Can Vet J. 2003;44(1):43\u201350."},{"issue":"1","key":"B4","series-title":"Vet Clin North Am Food Anim Pract","first-page":"97","article-title":"Evidence-based effectiveness of vaccination against Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in feedlot cattle for mitigating the incidence and effect of bovine respiratory disease complex","volume":"28","author":"Larson RL","year":"2012","unstructured":"Larson RL, Step DL. Evidence-based effectiveness of vaccination against Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in feedlot cattle for mitigating the incidence and effect of bovine respiratory disease complex. Vet Clin North Am Food Anim Pract. 2012;28(1):97\u2013106. doi:10.1016\/j.cvfa.2011.12.005"},{"issue":"4","key":"B5","series-title":"Evid Based Med","first-page":"125","article-title":"New evidence pyramid","volume":"21","author":"Murad MH","year":"2016","unstructured":"Murad MH, Asi N, Alsawas M, Alahdab F. New evidence pyramid. Evid Based Med. 2016;21(4):125\u2013127. doi:10.1136\/ebmed-2016-110401"},{"issue":"2","key":"B6","series-title":"Anim Health Res Rev","first-page":"106","article-title":"How to read and interpret the results of a Bayesian network meta-analysis: a short tutorial","volume":"20","author":"Hu D","year":"2019","unstructured":"Hu D, O\u2019Connor AM, Winder CB, Sargeant JM, Wang C. How to read and interpret the results of a Bayesian network meta-analysis: a short tutorial. Anim Health Res Rev. 2019;20(2):106\u2013115. doi:10.1017\/S1466252319000343"},{"key":"B7","series-title":"Front Vet Sci","first-page":"1235942","article-title":"Vaccine use in Canadian cow-calf herds and opportunities for improvement","volume":"10","author":"Lazurko MM","year":"2023","unstructured":"Lazurko MM, Erickson NEN, Campbell JR, Gow S, Waldner CL. Vaccine use in Canadian cow-calf herds and opportunities for improvement. Front Vet Sci. 2023;10:1235942. doi:10.3389\/fvets.2023.1235942"},{"issue":"3","key":"B8","series-title":"Vet Clin North Am Food Anim Pract","first-page":"575","article-title":"Vaccination management of beef cattle: delayed vaccination and endotoxin stacking","volume":"35","author":"Richeson JT","year":"2019","unstructured":"Richeson JT, Hughes HD, Broadway PR, Carroll JA. Vaccination management of beef cattle: delayed vaccination and endotoxin stacking. Vet Clin North Am Food Anim Pract. 2019;35(3):575\u2013592. doi:10.1016\/j.cvfa.2019.07.003"}],"container-title":["American Journal of Veterinary Research"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/86\/7\/ajvr.24.12.0389.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/86\/7\/ajvr.24.12.0389.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/ajvr\/86\/7\/ajvr.24.12.0389.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T13:00:32Z","timestamp":1751461232000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/86\/7\/ajvr.24.12.0389.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":8,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.2460\/ajvr.24.12.0389","relation":{},"ISSN":["0002-9645","1943-5681"],"issn-type":[{"type":"print","value":"0002-9645"},{"type":"electronic","value":"1943-5681"}],"subject":[],"published":{"date-parts":[[2025,7,1]]}}}