{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T02:37:10Z","timestamp":1770172630100,"version":"3.49.0"},"reference-count":30,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine median survival time using predefined creatinine percentage changes after SC ureteral bypass (SUB) placement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective cohort study. Data from cats admitted for SUB placement were collected between 2015 and 2022 from a single referral hospital. Serum creatinine values at presentation and at 24 and 48 hours after SUB placement and outcome data (dead or alive) were extracted, and percentage change was calculated. Cats with incomplete datasets or nonbenign obstruction were excluded. A priori decreases of 25% and 50% were regarded as acceptable changes at 24 or 48 hours, respectively. Median survival times were approximated using Kaplan-Meier curves.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Records from 21 of 30 cats (14 female, 7 male) that were a median of 8 (7 to 10) years old had complete datasets for analysis. Median survival times were 241 (8, 719) and 989 (989, 1,510) days for cats that did not and did achieve the predefined decrease at 24 hours, respectively. Median survival times were 225 (8, 387) and 989 (2, 1,510) days for cats that did not and did achieve the predefined decrease at 48 hours, respectively. The overall median survival time was 387 (119, 989) days regardless of achieving the predefined percentage decreases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The median survival time was significantly longer in cats that achieved or exceeded the predefined percentage reduction in creatinine at 24 or 48 hours after SUB placement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>Evaluating percentage changes in serial serum creatinine after SUB placement can be useful to indicate survival and longevity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.25.07.0276","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T13:38:10Z","timestamp":1763559490000},"source":"Crossref","is-referenced-by-count":0,"title":["Median survival times are longer in azotemic cats that have a 25% or 50% reduction in creatinine at 24 or 48 hours, respectively, after subcutaneous ureteral bypass device placement"],"prefix":"10.2460","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9560-6133","authenticated-orcid":true,"given":"Anika A.","family":"de Witt","sequence":"first","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genna F.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7653-7726","authenticated-orcid":true,"given":"Gareth E.","family":"Zeiler","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9960-2770","authenticated-orcid":true,"given":"Chad F.","family":"Berman","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa"},{"name":"Bryanston Veterinary Hospital, Bryanston, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-7309","authenticated-orcid":true,"given":"Ross C.","family":"Elliott","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa"},{"name":"Bryanston Veterinary Hospital, Bryanston, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"4","key":"B1","series-title":"Vet Clin North Am Small Anim Pract","first-page":"989","article-title":"Management of ureteral obstruction","volume":"34","author":"Hardie EM","year":"2004","unstructured":"Hardie EM, Kyles AE. Management of ureteral obstruction. Vet Clin North Am Small Anim Pract. 2004;34(4):989\u20131010. doi:10.1016\/j.cvsm.2004.03.008"},{"issue":"12","key":"B2","series-title":"J Feline Med Surg","first-page":"1052","article-title":"Predictors of outcome for cats with ureteral obstructions after interventional management using ureteral stents or a subcutaneous ureteral bypass device","volume":"15","author":"Horowitz C","year":"2013","unstructured":"Horowitz C, Berent A, Weisse C, Langston C, Bagley D. Predictors of outcome for cats with ureteral obstructions after interventional management using ureteral stents or a subcutaneous ureteral bypass device. J Feline Med Surg. 2013;15(12):1052\u20131062. doi:10.1177\/1098612X13489055"},{"issue":"2","key":"B3","series-title":"J Vet Intern Med","first-page":"222","article-title":"Feline ureteral strictures: 10 cases (2007-2009)","volume":"25","author":"Zaid MS","year":"2011","unstructured":"Zaid MS, Berent AC, Weisse C, Caceres A. Feline ureteral strictures: 10 cases (2007-2009). J Vet Intern Med. 2011;25(2):222\u2013229. doi:10.1111\/j.1939-1676.2011.0679.x"},{"issue":"2","key":"B4","series-title":"J Vet Emerg Crit Care (San Antonio)","first-page":"86","article-title":"Ureteral obstructions in dogs and cats: a review of traditional and new interventional diagnostic and therapeutic options","volume":"21","author":"Berent AC","year":"2011","unstructured":"Berent AC. Ureteral obstructions in dogs and cats: a review of traditional and new interventional diagnostic and therapeutic options. J Vet Emerg Crit Care (San Antonio). 2011;21(2):86\u2013103. doi:10.1111\/j.1476-4431.2011.00628.x"},{"key":"B5","series-title":"J Feline Med Surg","first-page":"15","article-title":"Feline CKD: diagnosis, staging. and screening - what is recommended?","volume":"15","author":"Paepe D","year":"2013","unstructured":"Paepe D, Daminet S. Feline CKD: diagnosis, staging. and screening - what is recommended? 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