{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:15:11Z","timestamp":1777904111813,"version":"3.51.4"},"reference-count":76,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To determine the efficacy of iodine disinfection and effect of storage on tilapia skin wound dressing via microbiological, histological, and spectroscopic assessment.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Farm-raised, fresh tilapias were included in this prospective ex vivo study conducted in September of 2024. Tilapia fish skin (TFS) was harvested and treated with 10% iodine or saline for 15 minutes. Each group was aseptically packaged, stored (4\u2009\u00b0C), and evaluated on days 0, 1, 3, and 7. Colony-forming units were counted from bacterial cultures. Structural integrity was determined histologically by collagen integrity (grade 0 to 3), organization (grade 0 to 3), and intensity (percentage). Lipid concentration was analyzed via gas chromatography\u2013mass spectrometry of extracted fish oil.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n 9 tilapias (n = 9) were enrolled. Mean bacterial counts following iodine and saline treatment were 0.56 \u00b1 0.88 CFUs\/mL and 19.67 \u00b1 6.12 CFUs\/mL, respectively. Iodine-treated TFS maintained disinfection after 7 days of storage (mean bacterial count, 4.11 \u00b1 3.48 CFUs\/mL). Mean collagen integrity grades following iodine treatment and 7 days of storage were 1.83 \u00b1 0.41 and 1.33 \u00b1 0.52, respectively. Mean collagen organization grades following iodine treatment and 7 days of storage were 1.83 \u00b1 0.41 and 2 \u00b1 0, respectively. Iodine-treated TFS collagen intensity was low throughout the study duration (range, 15.61% to 26.59%). Lipids were variably detectable in all samples. No eicosapentaenoic or docosahexaenoic acid was detected in any samples.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Iodine-disinfected, cold-stored TFS maintained disinfection and structural integrity for 7 days.<\/jats:p>\n <\/jats:sec>\n \n Clinical Relevance<\/jats:title>\n TFS can be readily harvested, disinfected, and stored. Future studies are needed for lipid profiling.<\/jats:p>\n <\/jats:sec>","DOI":"10.2460\/ajvr.25.08.0298","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T14:33:47Z","timestamp":1769524427000},"source":"Crossref","is-referenced-by-count":0,"title":["Iodine-treated, fresh tilapia fish skin graft maintains disinfection and structural integrity for 7 days with cold storage"],"prefix":"10.2460","volume":"87","author":[{"given":"Mary D.","family":"Kerby","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katelyn C.","family":"Hlusko","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharine A.","family":"Horzmann","sequence":"additional","affiliation":[{"name":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2491-3483","authenticated-orcid":true,"given":"Carlos E. 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