{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T02:41:16Z","timestamp":1770172876616,"version":"3.49.0"},"reference-count":68,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To assess the correlation, agreement, and trending ability between external jugular venous oxygen saturation (SejvO\n                      <jats:sub>2<\/jats:sub>\n                      ) and central venous oxygen saturation (ScvO\n                      <jats:sub>2<\/jats:sub>\n                      ) across varying hemodynamic states in anesthetized dogs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective, nonrandomized, repeated-measures study included 6 healthy dogs. Each dog was anesthetized, paralyzed, and mechanically ventilated. Six sequential hemodynamic states were induced: baseline, controlled hemorrhage, isotonic crystalloid resuscitation, autotransfusion, continuous rate infusion of dobutamine, and administration of high-concentration isoflurane. Simultaneous blood samples were collected from a central venous catheter and an external jugular venous catheter. Paired SejvO\n                      <jats:sub>2<\/jats:sub>\n                      and ScvO\n                      <jats:sub>2<\/jats:sub>\n                      values were analyzed for correlation, agreement, and trending ability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      36 paired samples were obtained. External jugular venous oxygen saturation and ScvO\n                      <jats:sub>2<\/jats:sub>\n                      were strongly correlated (\n                      <jats:italic>r<\/jats:italic>\n                      = 0.71; 95% CI, 0.50 to 0.84). Bland-Altman analysis showed a mean bias of \u22124.47% (95% CI, \u22127.34% to \u22121.60%) with limits of agreement from \u221214.25% (95% CI, \u221217.70% to \u221210.81%) to 5.31% (95% CI, 1.87% to 8.76%), exceeding the predefined \u00b1 8% threshold. The concordance rate was 66.7% (95% CI, 47.2% to 82.7%) and improved to 87.5% (95% CI, 61.7% to 98.4%) when applying an exclusion zone of \u00b1 5%, indicating moderate trending ability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      SejvO\n                      <jats:sub>2<\/jats:sub>\n                      correlated strongly with ScvO\n                      <jats:sub>2<\/jats:sub>\n                      but lacked sufficient agreement for direct substitution. However, it demonstrated moderate ability to track directional changes under different hemodynamic conditions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>\n                      SejvO\n                      <jats:sub>2<\/jats:sub>\n                      may serve as a less invasive option for serial monitoring of oxygen balance when direct ScvO\n                      <jats:sub>2<\/jats:sub>\n                      measurement is not feasible, supporting its potential role in critical care monitoring.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.25.09.0328","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T14:49:31Z","timestamp":1763650171000},"source":"Crossref","is-referenced-by-count":0,"title":["Relationship between external jugular and central venous oxygen saturation in anesthetized dogs under varying hemodynamic conditions"],"prefix":"10.2460","volume":"87","author":[{"given":"Nanju","family":"Lee","sequence":"first","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beomkwan","family":"Namgoong","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daeyun","family":"Seo","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seongsoo","family":"Lim","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isong","family":"Kim","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seunghun","family":"Heo","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihwan","family":"Kang","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheyoun","family":"Kim","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayoung","family":"Shin","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soyeon","family":"Park","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaewon","family":"Park","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of 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