{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T13:11:40Z","timestamp":1780060300162,"version":"3.54.0"},"reference-count":96,"publisher":"American Veterinary Medical Association (AVMA)","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe variations in blood glucose concentrations depending on their clinical diagnosis in a large cohort of chelonians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data on species, sex, habitat, blood glucose, appetite, organ category, and disease type data were extracted and analyzed using commercial statistical software. Generalized linear models were built to evaluate the association between blood glucose concentrations and organ system or disease type while accounting for other predictor variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After exclusion of healthy chelonians and chelonians missing glucose measurements, 967 chelonians were included in this study. The most represented chelonians were red-eared sliders (\n                      <jats:italic>Trachemys scripta elegans<\/jats:italic>\n                      ; n = 413), followed by African spurred tortoises (\n                      <jats:italic>Centrochelys sulcata<\/jats:italic>\n                      ; 102). After multivariable adjustment, compared to chelonians with trauma, chelonians with infectious disease, inflammatory disease, metabolic disease, neoplastic disease, and vascular disease had glucose concentrations that were 33.3% to 48.2% lower. Compared to chelonians with urinary tract involvement, chelonians with different organ systems affected had blood glucose concentrations 16.4% to 61.9% lower. There were no associations between gout, dystocia, or urolithiasis and glucose concentrations. Chelonians with hyperuricemia had blood glucose concentrations 47.8% higher than those without hyperuricemia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Blood glucose concentrations may vary in chelonian patients depending on the type of disease and the organ affected, among other factors. Certain conditions result in increased or decreased glucose concentrations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>When testing blood glucose in unhealthy chelonians, results should be interpreted considering species and disease context.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.26.01.0007","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T16:13:11Z","timestamp":1772813591000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical value of blood glucose concentrations in a large population of unhealthy client-owned chelonians"],"prefix":"10.2460","volume":"87","author":[{"given":"Marta","family":"Bakaj","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Violaine","family":"Colon","sequence":"additional","affiliation":[{"name":"Durrell Wildlife Conservation Trust, Trinity, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5203-9765","authenticated-orcid":true,"given":"Nicola","family":"Di Girolamo","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"1","key":"B1","series-title":"Biophys Rev","first-page":"5","article-title":"Glucose transporters: physiological and pathological roles","author":"Navale AM","year":"2016","unstructured":"Navale AM, Paranjape AN. 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