{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:20:52Z","timestamp":1783009252955,"version":"3.54.5"},"reference-count":26,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe outcomes following outpatient management of dogs with primary hyperparathyroidism treated with parathyroidectomy between 2015 and 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical records of 43 client-owned dogs with primary hyperparathyroidism treated with parathyroidectomy at a private specialty hospital (2015 to 2025) were observationally, retrospectively analyzed. Pre- and postoperative variables examined included demographics, biochemical markers (ionized calcium [iCa], parathyroid hormone, and parathyroid hormone-related protein), imaging and histopathology findings, postoperative iCa nadir and time to nadir, and incidence of hypocalcemia and supplementation. Data were compared between clinically hypocalcemic, nonclinically hypocalcemic, and normocalcemic groups. Morbidity and mortality over a 14-day follow-up period were reported. Feline patients, those without accessible medical records, and those hospitalized for unrelated illnesses were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No variables were significantly correlated with or predictive of clinical postoperative hypocalcemia. Dogs presenting with gastrointestinal upset (n = 6) had a significantly higher preoperative iCa than those without (37). The mean iCa nadir was significantly lower in dogs receiving supplementation (0.92; 95% CI, 0.85 to 0.98; n = 8) than those that did not (1.19; 95% CI, 1.15 to 1.23; 35). Three of 8 supplemented dogs demonstrated clinical signs before supplementation. One dog received emergent IV calcium. No mortality was reported over the 14-day follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Outpatient postparathyroidectomy management was not associated with mortality over 14 days. Hypocalcemia-related morbidity was transient, manageable, and infrequent. No predictive variables for clinical postoperative hypocalcemia were identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>Select postoperative parathyroidectomy patients can be managed on an outpatient basis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.26.01.0021","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T20:15:12Z","timestamp":1776456912000},"source":"Crossref","is-referenced-by-count":0,"title":["Retrospective evaluation of outpatient management following parathyroidectomy for treatment of primary hyperparathyroidism in dogs"],"prefix":"10.2460","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6976-9457","authenticated-orcid":true,"given":"Sarah M.","family":"Duke","sequence":"first","affiliation":[{"name":"Surgical Oncology Department, Colorado Animal Specialty and Emergency (CASE), Boulder, CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6027-4730","authenticated-orcid":true,"given":"Cassandra Y.","family":"Prpich","sequence":"additional","affiliation":[{"name":"Surgical Oncology Department, Colorado Animal Specialty and Emergency (CASE), Boulder, CO"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"5","key":"B1","series-title":"J Am Vet Med Assoc","first-page":"756","article-title":"Pretreatment clinical and laboratory findings in dogs with primary hyperparathyroidism: 210 cases (1987\u20132004)","author":"Feldman EC","year":"2005","unstructured":"Feldman EC, Hoar B, Pollard R, Nelson RW. Pretreatment clinical and laboratory findings in dogs with primary hyperparathyroidism: 210 cases (1987\u20132004). J Am Vet Med Assoc. 2005;227(5):756\u2013761. doi:10.2460\/javma.2005.227.756"},{"issue":"3","key":"B2","series-title":"J Am Vet Med Assoc","first-page":"350","article-title":"Primary hyperparathyroidism in dogs: 21 cases (1976\u20131986)","author":"Berger B","year":"1987","unstructured":"Berger B, Feldman EC. Primary hyperparathyroidism in dogs: 21 cases (1976\u20131986). J Am Vet Med Assoc. 1987;191(3):350\u2013356. doi:10.2460\/javma.1987.191.03.350"},{"issue":"4","key":"B3","series-title":"J Am Vet Med Assoc","first-page":"507","article-title":"Preoperative factors associated with postoperative hypocalcemia in dogs with primary hyperparathyroidism that underwent parathyroidectomy: 62 cases (2004\u20132009)","author":"Milovancev M","year":"2013","unstructured":"Milovancev M, Schmiedt CW. Preoperative factors associated with postoperative hypocalcemia in dogs with primary hyperparathyroidism that underwent parathyroidectomy: 62 cases (2004\u20132009). J Am Vet Med Assoc. 2013;242(4):507\u2013515. doi:10.2460\/javma.242.4.507"},{"key":"B4","series-title":"Veterinary Surgery: Small Animal","first-page":"2043","article-title":"Chapter 121: thyroid and parathyroid glands","author":"Seguin B","year":"2018","unstructured":"Seguin B, Brownlee L. Chapter 121: thyroid and parathyroid glands. In: Johnston SA, Tobias KM, eds. Veterinary Surgery: Small Animal (2nd ed). Elsevier; 2018:2043\u20132058."},{"issue":"2","key":"B5","series-title":"J Vet Intern Med","first-page":"349","article-title":"Association of hypercalcemia before treatment with hypocalcemia after treatment in dogs with primary hyperparathyroidism","author":"Dear JD","year":"2017","unstructured":"Dear JD, Kass PH, Della Maggiore AM, Feldman EC. 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Seizures associated with hypocalcemia in a Yorkshire terrier with protein-losing enteropathy. J Am Anim Hosp Assoc. 2015;51(6):380\u2013384. doi:10.5326\/JAAHA-MS-6205"},{"issue":"6","key":"B13","series-title":"Vet Radiol Ultrasound","first-page":"729","article-title":"Ultrasonographic size of the canine parathyroid gland may not correlate with histopathology","author":"Secrest S","year":"2019","unstructured":"Secrest S, Grimes J. Ultrasonographic size of the canine parathyroid gland may not correlate with histopathology. Vet Radiol Ultrasound. 2019;60(6):729\u2013733. doi:10.1111\/vru.12789"},{"issue":"5","key":"B1","series-title":"J Am Vet Med Assoc","first-page":"756","article-title":"Pretreatment clinical and laboratory findings in dogs with primary hyperparathyroidism: 210 cases (1987\u20132004)","author":"Feldman EC","year":"2005","unstructured":"Feldman EC, Hoar B, Pollard R, Nelson RW. 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J Am Vet Med Assoc. 2005;226(6):567\u2013574. doi:10.2460\/javma.2005.226.567"},{"issue":"2","key":"B11","series-title":"J Vet Intern Med","first-page":"e70016","article-title":"Plasma parathyroid hormone concentration as a predictor of postoperative hypocalcemia in dogs diagnosed with primary hyperparathyroidism and treated with parathyroidectomy","author":"Travail V","year":"2025","unstructured":"Travail V, van den Boom R, Rault D, et al. Plasma parathyroid hormone concentration as a predictor of postoperative hypocalcemia in dogs diagnosed with primary hyperparathyroidism and treated with parathyroidectomy. J Vet Intern Med. 2025;39(2):e70016. doi:10.1111\/jvim.70016"},{"issue":"6","key":"B12","series-title":"J Am Anim Hosp Assoc","first-page":"380","article-title":"Seizures associated with hypocalcemia in a Yorkshire terrier with protein-losing enteropathy","author":"Whitehead J","year":"2015","unstructured":"Whitehead J, Quimby J, Bayliss D. Seizures associated with hypocalcemia in a Yorkshire terrier with protein-losing enteropathy. J Am Anim Hosp Assoc. 2015;51(6):380\u2013384. doi:10.5326\/JAAHA-MS-6205"},{"issue":"6","key":"B13","series-title":"Vet Radiol Ultrasound","first-page":"729","article-title":"Ultrasonographic size of the canine parathyroid gland may not correlate with histopathology","author":"Secrest S","year":"2019","unstructured":"Secrest S, Grimes J. Ultrasonographic size of the canine parathyroid gland may not correlate with histopathology. 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