{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:03:28Z","timestamp":1785513808013,"version":"3.56.0"},"reference-count":29,"publisher":"American Veterinary Medical Association (AVMA)","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess right ventricular (RV) systolic function using conventional echocardiography and advanced techniques, including strain and tissue motion annular displacement (TMAD), in dogs with and without pulmonary hypertension (PH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Dogs with PH and healthy client-owned dogs (control group) evaluated from March 2018 through June 2022 were eligible for inclusion in this case-control study. Dogs in the PH group were classified as having either precapillary or postcapillary PH. All dogs underwent physical examination, blood pressure measurement, electrocardiography, and echocardiographic evaluation, including conventional and speckle-tracking techniques. Right ventricular systolic function was assessed using multiple variables, including TMAD, measured as midpoint displacement (millimeters), midpoint displacement relative to RV length (percentage), and TMAD indexed to body weight (mm\/kg) and body surface area (mm\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). The results were compared among groups and subgroups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 46 dogs in the PH group (precapillary PH, n = 27; postcapillary PH, 19) and 44 dogs in the control group. The TMAD values were lowest in dogs with precapillary PH compared with the control group and dogs with postcapillary PH. Tissue motion annular displacement (mm\/kg) showed weak to moderate positive correlations with RV structural variables and fractional area change percentage, a weak negative correlation with tricuspid annular plane systolic excursion normalized by body weight, and no significant correlation with peak velocity of systolic tricuspid annular motion as determined by tissue Doppler imaging (S\u2032).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TMAD does not replace conventional techniques for assessing RV systolic function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>The evaluated technique may serve as a supplementary tool for assessing RV systolic function in dogs with PH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.26.03.0107","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T16:21:55Z","timestamp":1779812515000},"source":"Crossref","is-referenced-by-count":0,"title":["Right ventricular systolic function in dogs with pulmonary hypertension can be assessed using tissue motion annular displacement"],"prefix":"10.2460","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0232-272X","authenticated-orcid":true,"given":"Vin\u00edcius Bentiv\u00f3glio Costa","family":"Silva","sequence":"first","affiliation":[{"name":"Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7685-2942","authenticated-orcid":true,"given":"Stephany Buba","family":"Lucina","sequence":"additional","affiliation":[{"name":"Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3068-6616","authenticated-orcid":true,"given":"Marcela","family":"Wolf","sequence":"additional","affiliation":[{"name":"Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5136-8209","authenticated-orcid":true,"given":"Ana Paula","family":"Sarraff","sequence":"additional","affiliation":[{"name":"Clinivet Veterinary Hospital, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4203-9283","authenticated-orcid":true,"given":"Luisa Fernanda Castillo","family":"Franco","sequence":"additional","affiliation":[{"name":"Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1367-9828","authenticated-orcid":true,"given":"Marlos Gon\u00e7alves","family":"Sousa","sequence":"additional","affiliation":[{"name":"Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"suppl 25","key":"B1","series-title":"J Am Coll Cardiol","first-page":"D42","article-title":"Definitions and diagnosis of pulmonary hypertension","author":"Hoeper MM","year":"2013","unstructured":"Hoeper MM, Bogaard HJ, Condliffe R, et al. 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Clin Exp Hypertens. 2023;45(1):2190503. doi:10.1080\/10641963.2023.2190503"},{"issue":"2","key":"B3","series-title":"J Vet Intern Med","first-page":"549","article-title":"ACVIM consensus statement guidelines for the diagnosis, classification, treatment, and monitoring of pulmonary hypertension in dogs","author":"Reinero C","year":"2020","unstructured":"Reinero C, Visser LC, Kellihan HB, et al. ACVIM consensus statement guidelines for the diagnosis, classification, treatment, and monitoring of pulmonary hypertension in dogs. J Vet Intern Med. 2020;34(2):549\u2013573. doi:10.1111\/jvim.15725"},{"key":"B4","series-title":"Pesq Vet Bras","first-page":"e06810","article-title":"Echocar\u00addiographic features of pre- and postcapillary pulmonary hypertension with a focus on the right ventricle in dogs","author":"Braz JB","year":"2021","unstructured":"Braz JB, Camacho AA, Canola RAM, et al. Echocar\u00addiographic features of pre- and postcapillary pulmonary hypertension with a focus on the right ventricle in dogs. Pesq Vet Bras. 2021;41:e06810. doi:10.1590\/1678-5150-PVB-6810"},{"issue":"8","key":"B5","series-title":"Front Vet Sci","first-page":"727155","article-title":"Right ventricular myocardial adaptation assessed by two-dimensional speckle tracking echocardiography in canine models of chronic pulmonary hypertension","author":"Yuchi Y","year":"2021","unstructured":"Yuchi Y, Suzuki R, Kanno H, Tehima T, Matsumoto H, Koyama H. Right ventricular myocardial adaptation assessed by two-dimensional speckle tracking echocardiography in canine models of chronic pulmonary hypertension. 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Int J Cardiovasc Imaging. 2017;33(9):1331\u20131339. doi:10.1007\/s10554-017-1110-6"},{"key":"B8","series-title":"J Vet Cardiol","first-page":"40","article-title":"Assessment of right ventricular systolic function by tissue motion annular displacement in healthy dogs","author":"Silva VB","year":"2020","unstructured":"Silva VB, Wolf M, Lucina SB, Sarraff-Lopes AP, Sousa MG. Assessment of right ventricular systolic function by tissue motion annular displacement in healthy dogs. J Vet Cardiol. 2020;32:40\u201348. doi:10.1016\/j.jvc.2020.09.010"},{"issue":"11","key":"B9","series-title":"Appl Sci","first-page":"5494","article-title":"A novel speckle-tracking echocardiography derived parameter that predicts clinical worsening in children with pulmonary arterial hypertension","author":"Muntean I","year":"2022","unstructured":"Muntean I, Melinte M, F\u0103g\u0103r\u0103\u0219an A, \u0218uteu CC, Tog\u0103nel R. 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