{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:11:00Z","timestamp":1788883860587,"version":"build-2803163510"},"reference-count":67,"publisher":"American Veterinary Medical Association (AVMA)","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To investigate the nasal carriage of\n                      <jats:italic>Cryptococcus<\/jats:italic>\n                      -related and other opportunistic yeasts in dogs, molecularly characterize the recovered isolates, and evaluate the epidemiological characteristics of\n                      <jats:italic>Naganishia albida<\/jats:italic>\n                      carriage.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Nasal swab samples were collected from July through December 2023 from 100 dogs receiving boarding or hospitalization services at private veterinary clinics and animal hospitals in 4 provinces of T\u00fcrkiye. Yeast isolates were identified using phenotypic methods, internal transcribed spacer 2 sequencing, and matrix-assisted laser desorption ionization\u2013time-of-flight mass spectrometry. The 1-year clinical history of dogs carrying\n                      <jats:italic>N albida<\/jats:italic>\n                      was retrospectively reviewed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 79 isolates representing 31 yeast species were identified from 59 dogs.\n                      <jats:italic>Cryptococcus neoformans<\/jats:italic>\n                      \/\n                      <jats:italic>gattii<\/jats:italic>\n                      species complex organisms were not isolated from any dog.\n                      <jats:italic>Naganishia albida<\/jats:italic>\n                      and\n                      <jats:italic>Papiliotrema laurentii<\/jats:italic>\n                      were isolated from 12% and 1% of dogs, respectively.\n                      <jats:italic>Naganishia albida<\/jats:italic>\n                      carriage was detected in both clinically healthy and clinically affected dogs, with higher frequencies observed among dogs presenting with respiratory, dermatological, or systemic clinical findings. However, no significant associations were identified between\n                      <jats:italic>N albida<\/jats:italic>\n                      carriage and the evaluated epidemiological variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Dogs may harbor diverse opportunistic yeasts, including\n                      <jats:italic>Cryptococcus<\/jats:italic>\n                      -related yeasts, within the nasal cavity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>Opportunistic yeasts can colonize the nasal cavities of both clinically healthy and clinically affected dogs. These findings provide baseline epidemiological data for interpreting fungal culture results and contribute to a better understanding of opportunistic fungal carriage in companion animals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.26.06.0278","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:48:19Z","timestamp":1788882499000},"page":"1-9","source":"Crossref","is-referenced-by-count":0,"title":["Cryptococcus-targeted culture in dogs reveals nasal carriage of Naganishia albida and diverse opportunistic yeasts with potential clinical relevance"],"prefix":"10.2460","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0560-2074","authenticated-orcid":true,"given":"Enes Said","family":"G\u00fcnd\u00fcz","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine, Department of Microbiology, Erciyes University, Kayseri, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6326-0377","authenticated-orcid":true,"given":"Kadir Semih","family":"G\u00fcm\u00fc\u015fsoy","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Department of Microbiology, Erciyes University, Kayseri, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1736-9707","authenticated-orcid":true,"given":"Ay\u015fe Nedret","family":"Ko\u00e7","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Medical Microbiology, Erciyes University, Kayseri, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"B1","series-title":"Cryptococcus: from Human Pathogen to Model Yeast","first-page":"3","article-title":"Systematics of the genus Cryptococcus and its type species C.neoformans","author":"Kwon-Chung KJ","year":"2010","unstructured":"Kwon-Chung KJ, Boekhout T, Wickes BL, Fell JW. 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