{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:46:09Z","timestamp":1792615569041,"version":"4.5.0"},"reference-count":31,"publisher":"American Veterinary Medical Association (AVMA)","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2026,10,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"sc_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe posthepatectomy hypophosphatemia in dogs and evaluate whether the extent of hepatectomy was associated with postoperative hypophosphatemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective, observational study of dogs that underwent hepatectomy from January 1, 2019, through December 15, 2025, with serum phosphorus concentrations recorded preoperatively and within 72 hours postoperatively. Dogs with comorbidities or complications expected to influence serum phosphorus were excluded. Data included extent of hepatectomy (division\/subdivisional) and change in serum phosphorus concentration (\u0394P). Phosphorus and the proportions of dogs with recorded hypophosphatemia were compared between dogs undergoing division hepatectomy and subdivisional hepatectomy using the Mann-Whitney test and Fisher\u2019s exact test, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>42 dogs were included (19 subdivisional, 23 division hepatectomy). Median \u0394P was \u22120.8 mg\/dL (range, \u22123.8 to 3.4). \u0394P was greater in dogs with division hepatectomy (\u22120.9 mg\/dL; range, \u22123.8 to 3.4) than subdivisional hepatectomy (\u22120.5 mg\/dL; range, \u22121.7 to 1.2). Seven of 42 dogs (16.7%) developed postoperative hypophosphatemia at a median of 20 hours (range, 16 to 43); all dogs had undergone division hepatectomy (7 of 23 [30.4%]). Three dogs were treated with IV potassium phosphate. No dogs (0 of 19 [0%]) with subdivisional hepatectomy had recorded hypophosphatemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hypophosphatemia can arise in dogs after liver resection, primarily following division hepatectomy or greater. There was an overall decrease in phosphorus for both divisional and subdivisional hepatectomy groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sc_a5\">\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>Routine assessment of phosphorus following hepatectomy may be considered to minimize the risk of consequential hypophosphatemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/ajvr.26.08.0332","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:03:10Z","timestamp":1792612990000},"page":"1-7","source":"Crossref","is-referenced-by-count":0,"title":["Acute postoperative hypophosphatemia is a potential sequela following hepatectomy in dogs"],"prefix":"10.2460","author":[{"given":"Rachel E.","family":"Bryant","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3765-429X","authenticated-orcid":true,"given":"Owen T.","family":"Skinner","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Barchilon","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"3","key":"B1","series-title":"Hepatobiliary Surg Nutr","first-page":"217","article-title":"Hypophosphatemia and recovery of post-hepatectomy liver insufficiency","volume":"5","author":"Hallet J","year":"2016","unstructured":"Hallet J, Karanicolas PJ, Zih FSW, et al. Hypophosphatemia and recovery of post-hepatectomy liver insufficiency. Hepatobiliary Surg Nutr. 2016;5(3):217\u2013224. doi:10.21037\/hbsn.2015.12.13"},{"issue":"3","key":"B2","series-title":"Surgery","first-page":"448","article-title":"Hypophosphatemia after live donor right hepatectomy","volume":"144","author":"Lee HW","year":"2008","unstructured":"Lee HW, Suh KS, Kim J, et al. Hypophosphatemia after live donor right hepatectomy. Surgery. 2008;144(3):448\u2013453. doi:10.1016\/j.surg.2008.04.016"},{"issue":"10","key":"B3","series-title":"HPB","first-page":"884","article-title":"Hypophosphataemia after major hepatectomy and the risk of post-operative hepatic insufficiency and mortality: an analysis of 719 patients","volume":"16","author":"Squires MH","year":"2014","unstructured":"Squires MH, Dann GC, Lad NL, et al. Hypophosphataemia after major hepatectomy and the risk of post-operative hepatic insufficiency and mortality: an analysis of 719 patients. 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