{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:19:25Z","timestamp":1790180365945,"version":"4.1.0"},"reference-count":100,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To determine the effect of a controlled-release monensin capsule administered at cessation of lactation on incidence of calving-related disorders, fertility, and milk yield in dairy cows.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals<\/jats:bold>\n                    \u2014290 dairy cows treated with monensin and 290 untreated control cows.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedure<\/jats:bold>\n                    \u2014Treated cows received a capsule that released monensin at 335 mg\/d for 95 days. Incidence of calving-related disorders; daily milk yield up to 20 days postpartum; test-day milk yield, fat, protein, and mature-equivalent 305-day milk production; and body condition score at calving were determined. Reproductive variables were conception rate at first service, pregnancy rate, and calving-to-conception interval.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u2014Cows treated with monensin were 2.1 times as likely to develop dystocia and 0.8 times as likely to develop metritis as control cows. For milk yield, there was an interaction of treatment \u00d7time \u00d7parity. In multiparous cows, monensin significantly improved milk yield at test days 4 and 7. In addition, monensin increased body condition score at calving.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014Despite increasing the likelihood of developing dystocia and metritis, administration of monensin improved the lactational performance of multiparous cows and may be a promising additive for use at the time of cessation of lactation.\n                  <\/jats:p>","DOI":"10.2460\/ajvr.67.3.537","type":"journal-article","created":{"date-parts":[[2006,2,28]],"date-time":"2006-02-28T17:22:05Z","timestamp":1141147325000},"page":"537-543","source":"Crossref","is-referenced-by-count":9,"title":["Effect of administration of a controlled-release monensin capsule on incidence of calving-related disorders, fertility, and milk yield in dairy cows"],"prefix":"10.2460","volume":"67","author":[{"given":"Pedro","family":"Melendez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse P.","family":"Goff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.","family":"Risco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis F.","family":"Archbald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon C.","family":"Littell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Arthur","family":"Donovan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Anim Sci","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.2527\/1995.7392820x","article-title":"Impact of changes in organic nutrient metabolism on feeding the transition dairy cow","volume":"73","author":"Grummer","year":"1995"},{"key":"ref2","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.3168\/jds.S0022-0302(98)70142-0","article-title":"Recommendations for recording and calculating the incidence of selected clinical diseases of dairy cattle","volume":"81","author":"Kelton","year":"1998"},{"key":"ref3","series-title":"Prev Vet Med","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0167-5877(99)00035-5","article-title":"Effects of disease on milk production in the dairy cow: a 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7th revised ed","year":"2001"},{"key":"ref14","series-title":"Veterinary epidemiologic research","first-page":"27","article-title":"Sample size","author":"Dohoo","year":"2003"},{"key":"ref15","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","author":"Ferguson","year":"1994"},{"key":"ref16","series-title":"SAS system for mixed models","author":"Littell","year":"1996"},{"key":"ref17","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"2939","DOI":"10.3168\/jds.S0022-0302(84)81657-4","article-title":"Manipulating dietary anions and cations for prepartum dairy cows to reduce incidence of milk fever","volume":"67","author":"Block","year":"1984"},{"key":"ref18","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"3863","DOI":"10.3168\/jds.S0022-0302(91)78579-2","article-title":"Addition 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cattle","volume":"16","author":"Duffield","year":"2000"},{"key":"ref38","series-title":"Herd health: food animal production medicine","first-page":"159","article-title":"Culling and genetic improvement programs for dairy herds","author":"Radostits","year":"1994"},{"key":"ref39","series-title":"J Anim Sci","doi-asserted-by":"publisher","first-page":"396","DOI":"10.2527\/1998.762396x","article-title":"Average daily gain, blood metabolites, and body composition at first conception in Hereford, Senepol, and reciprocal crossbred heifers on two levels of winter nutrition and two summer grazing treatments","volume":"76","author":"Simpson","year":"1998"},{"key":"ref40","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3168\/jds.S0022-0302(92)77760-1","article-title":"Effect of monensin on growth, reproductive performance, and estimated body composition in Holstein heifers","volume":"75","author":"Meinert","year":"1992"},{"key":"ref41","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3168\/jds.S0022-0302(98)75593-6","article-title":"Effect of monensin on milk production by Holstein and Jersey cows","volume":"81","author":"Van der Werf","year":"1998"},{"key":"ref42","series-title":"J Dairy Sci","doi-asserted-by":"publisher","first-page":"2789","DOI":"10.3168\/jds.S0022-0302(00)75176-9","article-title":"Effect of monensin on milk production of Holstein-Friesian dairy cows","volume":"83","author":"Phipps","year":"2000"},{"key":"ref43","series-title":"Aust Vet J","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1751-0813.1994.tb03444.x","article-title":"Effects of sodium monensin on reproductive performance of dairy cattle. 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