{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:25:47Z","timestamp":1770218747556,"version":"3.49.0"},"reference-count":52,"publisher":"American Veterinary Medical Association (AVMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To establish the reference ranges for motor evoked potential (MEP) latency and amplitude in clinically normal Doberman Pinschers, compare the MEPs of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy (CSM; wobbler syndrome), and determine whether MEP data correlate with neurologic or magnetic resonance imaging (MRI) findings.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201416 clinically normal and 16 CSM-affected Doberman Pinschers.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Dogs were classified according to their neurologic deficits. After sedation with acepromazine and hydromorphone, transcranial magnetic MEPs were assessed in each dog; latencies and amplitudes were recorded from the extensor carpi radialis and cranial tibial muscles. Magnetic resonance imaging was performed to evaluate the presence and severity of spinal cord compression.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Significant differences in cranial tibial muscle MEP latencies and amplitudes were detected between clinically normal and CSM-affected dogs. No differences in the extensor carpi radialis MEP were detected between groups. There was a significant correlation (<jats:italic>r<\/jats:italic> = 0.776) between the cranial tibial muscle MEP latencies and neurologic findings. Significant correlations were also found between MRI findings and the cranial tibial muscle MEP latencies (<jats:italic>r<\/jats:italic> = 0.757) and amplitudes (<jats:italic>r<\/jats:italic> = \u22120.453).<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results provided a reference range for MEPs in clinically normal Doberman Pinschers and indicated that cranial tibial muscle MEP latencies correlated well with both MRI and neurologic findings. Because of the high correlation between cranial tibial muscle MEP data and neurologic and MRI findings, MEP assessment could be considered as a screening tool in the management of dogs with spinal cord disease.<\/jats:p>","DOI":"10.2460\/ajvr.67.9.1613","type":"journal-article","created":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T13:56:18Z","timestamp":1157118978000},"page":"1613-1620","source":"Crossref","is-referenced-by-count":25,"title":["Correlation of motor evoked potentials with magnetic resonance imaging and neurologic findings in Doberman Pinschers with and without signs of cervical spondylomyelopathy"],"prefix":"10.2460","volume":"67","author":[{"given":"Ronaldo C.","family":"da Costa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Poma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joane M.","family":"Parent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Partlow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle","family":"Monteith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"917","article-title":"Caudal cervical vertebral malformation-malarticulation in Great Danes and Doberman Pinschers","volume":"168","author":"Trotter","year":"1976"},{"key":"ref2","series-title":"Vet Clin North Am Small Anim Pract","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/S0195-5616(88)50061-X","article-title":"Disc-associated wobbler syndrome in the Doberman pinscher","volume":"18","author":"VanGundy","year":"1988"},{"key":"ref3","series-title":"J Am Anim Hosp Assoc","first-page":"241","article-title":"Pathophysiology and diagnosis of caudal cervical spondylo-myelopathy with emphasis on the Doberman Pinscher","volume":"18","author":"Seim","year":"1982"},{"key":"ref4","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1111\/j.1748-5827.1999.tb02997.x","article-title":"Management of cervical spondylopathy-associated intervertebral, disc protrusions using metal washers in 78 dogs","volume":"40","author":"McKee","year":"1999"},{"key":"ref5","series-title":"Vet Rec","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1136\/vr.104.7.142","article-title":"Cervical vertebral instability (wobbler syndrome) in the dog","volume":"104","author":"Mason","year":"1979"},{"key":"ref6","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1111\/j.1748-5827.1989.tb01909.x","article-title":"Cervical spondylomyelopathy (\u2018wobbler\u201d syndrome) in the dog: a study based on 224 cases","volume":"30","author":"Lewis","year":"1989"},{"key":"ref7","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1111\/j.1748-5827.1992.tb01032.x","article-title":"Radiological evaluation of \u2018wobbler\u201d syndrome\u2014caudal cervical spondylomyelopathy","volume":"33","author":"Sharp","year":"1992"},{"key":"ref8","series-title":"Vet Radiol Ultrasound","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1111\/j.1740-8261.1995.tb00224.x","article-title":"Computed tomography in the evaluation of caudal cervical spondylomyelopathy of the Doberman Pinscher","volume":"36","author":"Sharp","year":"1995"},{"key":"ref9","series-title":"Vet Radiol Ultrasound","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/j.1740-8261.2001.tb00899.x","article-title":"Magnetic resonance imaging features of cervical stenotic myelopathy in 21 dogs","volume":"42","author":"Lipsitz","year":"2001"},{"key":"ref10","series-title":"Spine","first-page":"123","article-title":"Surgical decompressive procedures for cervical spondylotic myelopathy. 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