{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T02:36:52Z","timestamp":1785811012333,"version":"3.56.0"},"reference-count":62,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective\u2014<\/jats:bold>\n                    To determine effects of 2 doses of caffeine on metabolic variables in neonata pigs with peripartum asphyxia\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals\u2014<\/jats:bold>\n                    180 neonatal pigs\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedures\u2014<\/jats:bold>\n                    Neonatal pigs were assigned to 2 groups (groups P and F) on the basis of results for a vitality scale (passed or failed, respectively). Within each group, there were 3 subgroups of 30 pigs each. Within each group, the 3 subgroups received a placebo that consisted of an empty gelatin capsule, a gelatin capsule that contained 20 mg of caffeine, and a gelatin capsule that contained 35 mg of caffeine, respectively; all capsules were administered orally (0 hours). Blood samples were collected immediately before and 24 hours after capsule administration.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2014<\/jats:bold>\n                    Pigs in groups P and F that received 20 or 35 mg of caffeine had significant increases in triglyceride concentrations. All pigs in groups P and F had a significant decrease in lactate concentrations, although the placebo-treated pigs in group F had larger decreases than did the group F pigs treated with 20 or 35 mg of caffeine. Glucose concentrations increased significantly in group F pigs treated with 20 or 35 mg of caffeine (30% and 50%, respectively), whereas glucose concentrations remained unchanged in group P pigs. In pigs treated with 35 mg of caffeine, the final weight obtained for group F was approximately 8% lower than that obtained for group P\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance\u2014<\/jats:bold>\n                    Administering caffeine immediately after birth to neonatal pigs with severe oxygen restriction resulted in significant improvements in metabolic variables. (Am J Vet Res 2010;71:1214-1219)\n                  <\/jats:p>","DOI":"10.2460\/ajvr.71.10.1214","type":"journal-article","created":{"date-parts":[[2010,10,4]],"date-time":"2010-10-04T17:04:00Z","timestamp":1286211840000},"page":"1214-1219","source":"Crossref","is-referenced-by-count":35,"title":["Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia"],"prefix":"10.2460","volume":"71","author":[{"given":"H\u00e9ctor","family":"Orozco-Gregorio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Mota-Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herlinda","family":"Bonilla-Jaime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda 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