{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:45:23Z","timestamp":1773002723788,"version":"3.50.1"},"reference-count":38,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To assess relationships of acetabular volume (AV), femoral head volume (FV), and portion of the femoral head within in the acetabulum (FVIA) with each other and with degrees of hip joint laxity and degenerative joint disease from youth to maturity in dogs predisposed to developing hip joint osteoarthritis (OA).<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201446 mixed-breed half- or full-sibling hound-type dogs.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014The distraction index (DI), AV, FV, FVIA, and degree of osteoarthritis (OA score) were quantified in 1 hip joint at 16, 32, and 104 weeks of age. Relationships among variables were evaluated within and between ages. Ratios corresponding to OA scores were compared within ages. Differences among 16-week ratios corresponding to 32-week OA scores and among 16- and 32-week ratios corresponding to 104-week OA scores were evaluated.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Significant positive relationships existed between FV and AV across ages as well as between FVIA\/FV and FVIA\/AV and between DI and OA score across and within most ages. Such relationships also existed within these variables across most ages. Negative relationships of DI and OA scores with FVIA\/FV and FVIA\/AV within and among all ages were significant. Sixteen-week AVs, FVs, and FVIAs were greater and FV\/AVs and OA scores were less than 32- and 104-week values. The 32-week FVIA\/FV was less than 16- and 104-week values, and the 32-week FVIA\/AV was less than the 104-week value. The FVIA\/FV and FVIA\/AV were lower and the DI was higher with higher OA scores within and among most ages.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Structural volumes in lax canine hip joints changed predictably relative to each other during growth, despite degenerative changes. Measures developed in this study may augment current diagnosis and treatment strategies for hip dysplasia in dogs.<\/jats:p>","DOI":"10.2460\/ajvr.72.3.376","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T05:12:31Z","timestamp":1299042751000},"page":"376-383","source":"Crossref","is-referenced-by-count":11,"title":["Relationships of hip joint volume ratios with degrees of joint laxity and degenerative disease from youth to maturity in a canine population predisposed to hip joint osteoarthritis"],"prefix":"10.2460","volume":"72","author":[{"given":"Laura L.","family":"D'Amico","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey K.","family":"Abell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine T.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandi J.","family":"Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Pathol","first-page":"234","article-title":"The dog as a model for the study of hip dysplasia. Growth, form, and development of the normal and dysplastic hip joint","volume":"12","author":"Riser","year":"1975"},{"key":"ref2","series-title":"North Am Vet J","first-page":"53","article-title":"The veterinary radiologist: regional radiography\u2014the pelvic region\u2014part I","volume":"18","author":"Schnelle","year":"1937"},{"key":"ref3","series-title":"University of Pennsylvania Bulletin","first-page":"15","article-title":"Bilateral congenital subluxation of the coxofemoral joints in a dog","volume":"37","author":"Schnelle","year":"1937"},{"key":"ref4","series-title":"Semin Arthritis Rheum","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/0049-0172(80)90015-3","article-title":"Coxarthrosis: a study of the natural history based on a correlation of clinical, radiographic, and pathologic findings","volume":"10","author":"Macys","year":"1980"},{"key":"ref5","series-title":"J Am Anim Hosp Assoc","doi-asserted-by":"publisher","first-page":"339","DOI":"10.5326\/15473317-34-4-339","article-title":"Early detection of canine hip dysplasia: comparison of two palpation and five radio-graphic methods","volume":"34","author":"Adams","year":"1998"},{"key":"ref6","series-title":"Am J Vet Res","doi-asserted-by":"publisher","first-page":"362","DOI":"10.2460\/ajvr.69.3.362","article-title":"Relationships among measurements obtained by use of computed tomography and radiography and scores of cartilage microdamage in hip joints with moderate to severe joint laxity of adult dogs","volume":"69","author":"Lopez","year":"2008"},{"key":"ref7","series-title":"Vet Surg","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1111\/j.1532-950X.1998.tb00146.x","article-title":"Dorsolateral subluxation of hip joints in dogs measured in a weight-bearing position with radiography and computed tomography","volume":"27","author":"Farese","year":"1998"},{"key":"ref8","series-title":"J Am Vet Med Assoc","first-page":"59","article-title":"New concepts of coxofemoral joint stability and the development of a clinical stress-radio-graphic method for quantitating hip joint laxity in the dog","volume":"196","author":"Smith","year":"1990"},{"key":"ref9","series-title":"Radiol Clin North Am","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/S0033-8389(22)00467-5","article-title":"Imaging of osteoarthritis","volume":"34","author":"Preidler","year":"1996"},{"key":"ref10","series-title":"Eur J Radiol","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.ejrad.2005.10.003","article-title":"Position of the acetabular cup\u2014accuracy of radiographic calculation compared to CT-based measurement","volume":"58","author":"Kalteis","year":"2006"},{"key":"ref11","series-title":"Ann R Coll Surg Engl","first-page":"127","article-title":"Non-invasive imaging techniques in surgery","volume":"66","author":"Khan","year":"1984"},{"key":"ref12","series-title":"J Am Vet Med Assoc","first-page":"1142","article-title":"Reliability of early radiographic evaluations for canine hip dysplasia obtained from the standard ventrodorsal radiographic projection","volume":"211","author":"Corley","year":"1997"},{"key":"ref13","series-title":"Orthop Rev","first-page":"1189","article-title":"2-D and 3-D computed tomography and magnetic resonance imaging in developmental dysplasia of the hip","volume":"21","author":"Atar","year":"1992"},{"key":"ref14","series-title":"HSS J","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1007\/s11420-006-9026-z","article-title":"CT evaluation of total hip arthroplasty complication: dissociation of acetabular component","volume":"3","author":"Bogner","year":"2007"},{"key":"ref15","series-title":"J Pediatr Orthop","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1097\/00004694-199703000-00004","article-title":"Three-dimensional computer analysis of complex acetabular insufficiency","volume":"17","author":"Roach","year":"1997"},{"key":"ref16","series-title":"Iowa Orthop J","first-page":"20","article-title":"Three-dimensional CT modeling versus traditional radiology techniques in treatment of acetabular fractures","volume":"21","author":"Brown","year":"2001"},{"key":"ref17","series-title":"J Child Orthop","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s11832-007-0063-z","article-title":"Three-dimensional tomography analysis and anteversion study after periacetabular osteotomy of pelvis in children","volume":"1","author":"Jawish","year":"2007"},{"key":"ref18","series-title":"Skeletal Radiol","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s002560050397","article-title":"Three-dimensional CT measurement of adult acetabular dysplasia: technique, preliminary results in normal subjects, and potential applications","volume":"27","author":"Janzen","year":"1998"},{"key":"ref19","series-title":"Eur J Radiol","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/S0720-048X(00)00156-X","article-title":"Three-dimensional imaging of acetabular dysplasia: diagnostic value and impact on surgical type classification","volume":"34","author":"Smet","year":"2000"},{"key":"ref20","series-title":"Skeletal Radiol","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s00256-008-0601-x","article-title":"Three-dimensional computed tomography analysis of non-osteoarthritic adult acetabular dyplasia","volume":"38","author":"Ito","year":"2009"},{"key":"ref21","series-title":"J Orthop Res","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.orthres.2003.08.004","article-title":"Mechanobiological predictions of growth front morphology in developmental hip dysplasia","volume":"22","author":"Shefelbine","year":"2004"},{"key":"ref22","series-title":"J Pediatr Orthop","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1097\/01241398-199107000-00015","article-title":"The acetabulum in congenital and neuromuscular hip instability","volume":"11","author":"Buckley","year":"1991"},{"key":"ref23","series-title":"Am J Vet Res","first-page":"1021","article-title":"Coxofemoral joint laxity from distraction radiography and its contemporaneous and prospective correlation with laxity, subjective score, and evidence of degenerative joint disease from conventional hip-extended radiography in dogs","volume":"54","author":"Smith","year":"1993"},{"key":"ref24","series-title":"Am J Vet Res","first-page":"1076","article-title":"Within-and between-examiner repeatability of distraction indices of the hip joints in dogs","volume":"58","author":"Smith","year":"1997"},{"key":"ref25","series-title":"Skeletal Radiol","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1007\/s00256-005-0061-5","article-title":"Reliability of the Crowe and Hartofilakidis classifications used in the assessment of the adult dysplastic hip","volume":"35","author":"Decking","year":"2006"},{"key":"ref26","series-title":"Acta Orthop","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1080\/17453670610012665","article-title":"Computed tomography measurement of acetabular dimensions: normal values for correction of dysplasia","volume":"77","author":"Tallroth","year":"2006"},{"key":"ref27","series-title":"Skeletal Radiol","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1007\/s00256-005-0019-7","article-title":"Degeneration in dysplastic hips: a computed tomography study","volume":"34","author":"Jacobsen","year":"2005"},{"key":"ref28","series-title":"Vet Surg","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1053\/jvet.2001.23350","article-title":"Effects of pubic symphysiodesis in dysplastic puppies","volume":"30","author":"Dueland","year":"2001"},{"key":"ref29","series-title":"Vet Surg","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1053\/jvet.2002.34766","article-title":"Juvenile pubic symphysiodesis in dysplastic puppies at 15 and 20 weeks of age","volume":"31","author":"Patricelli","year":"2002"},{"key":"ref30","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"206","DOI":"10.2460\/javma.230.2.206","article-title":"Long-term outcome of juvenile pubic symphysiodesis and triple pelvic osteotomy in dogs with hip dysplasia","volume":"230","author":"Manley","year":"2007"},{"key":"ref31","series-title":"J Vet Med Sci","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1292\/jvms.71.247","article-title":"Quantitative evaluation of hip joint laxity in 22 border collies using computed tomography","volume":"71","author":"Kishimoto","year":"2009"},{"key":"ref32","series-title":"Am J Vet Res","doi-asserted-by":"publisher","first-page":"730","DOI":"10.2460\/ajvr.68.7.730","article-title":"Computed tomographic evaluation of growth-related changes in the hip joints of young dogs","volume":"68","author":"Fujiki","year":"2007"},{"key":"ref33","series-title":"J Vet Med Sci","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1292\/jvms.66.1003","article-title":"Laxity of canine hip joint in two positions with computed tomography","volume":"66","author":"Fujiki","year":"2004"},{"key":"ref34","series-title":"J Pediatr Orthop","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1097\/00004694-199703000-00003","article-title":"Three-dimensional characteristics of cartilaginous and bony components of dysplastic hips in children: three-dimensional computed tomography quantitative analysis","volume":"17","author":"Lin","year":"1997"},{"key":"ref35","series-title":"Int Orthop","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s00264-006-0257-x","article-title":"Quantitative computer-assisted osteodensitometry in total hip arthroplasty","volume":"31","author":"Pitto","year":"2007"},{"key":"ref36","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s11999-008-0522-y","article-title":"Can the volume of pelvic osteolysis be calculated without using computed tomography?","volume":"467","author":"Egawa","year":"2009"},{"key":"ref37","series-title":"J Orthop Surg Res","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1749-799X-1-6","article-title":"Cartilage contact pressure elevations in dysplastic hips: a chronic overload model","volume":"1","author":"Russell","year":"2006"},{"key":"ref38","series-title":"Trends Biomater Artif Organs","first-page":"63","article-title":"Three-dimensional anatomic finite element modelling of hemi-arthroplasty of human hip joint","volume":"21","author":"Cilingir","year":"2007"}],"container-title":["American Journal of Veterinary 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