{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:44:24Z","timestamp":1777563864399,"version":"3.51.4"},"reference-count":20,"publisher":"American Veterinary Medical Association (AVMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine MRI characteristics of the skulls and brains of sheep with chronic cerebral coenurosis (CC) caused by naturally acquired <jats:italic>Taenia multiceps<\/jats:italic> infection.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201433 sheep with CC and 10 healthy control sheep.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Sheep underwent MRI of the head. Volumes of the cranial cavity and rostral and caudal fossas of the cranial cavity were determined. For CC-affected sheep, the number, location, and volume of <jats:italic>T multiceps<\/jats:italic> cysts were determined and the percentage volumes of cysts in the cranial cavity and rostral and caudal fossas of the cranial cavity were calculated. Focal and diffuse abnormalities of cranial bones in CC-affected sheep were identified. Brain edema and hemorrhage and signs of increased cranial pressure (ICP) in MRI images were determined.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Volumes of the cranial cavity and rostral and caudal fossas of the cranial cavity were significantly larger for CC-affected sheep versus healthy control sheep. Total volumes of cysts ranged from 4.40% to 46.93% in cranial cavities of sheep, 4.12% to 51.53% in rostral fossas of cranial cavities of sheep, and 15.24% to 68.30% in caudal fossas of cranial cavities of sheep. Moderate to severe diffuse cranial bone abnormalities and signs of increased ICP in MRI images were detected in 21 and 24 sheep, respectively, and were positively correlated with cyst volumes.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggested that cranial cavity volume and morphological abnormalities can be detected in sheep with CC. These changes may reflect abnormalities in ossification of the cranial bones secondary to chronically increased ICP caused by development of <jats:italic>T multiceps<\/jats:italic> cysts.<\/jats:p>","DOI":"10.2460\/ajvr.73.12.1913","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T17:26:48Z","timestamp":1353691608000},"page":"1913-1918","source":"Crossref","is-referenced-by-count":22,"title":["Magnetic resonance imaging of the brain and skull of sheep with cerebral coenurosis"],"prefix":"10.2460","volume":"73","author":[{"given":"Maria L.","family":"Manunta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria A.","family":"Evangelisti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni P.","family":"Burrai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicol\u00f2","family":"Columbano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciriaco","family":"Ligios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Varcasia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Scala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eraldo","family":"Sanna Passino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"964","DOI":"10.3171\/jns.2004.100.5.0964","article-title":"Cerebral coenurosis. 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