{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:29:18Z","timestamp":1777375758282,"version":"3.51.4"},"reference-count":32,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To identify ventilatory protocols that yielded good image quality for thoracic CT and hemodynamic stability in cats.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u20147 healthy cats.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Cats were anesthetized and ventilated via 4 randomized protocols (hyperventilation, 20 seconds [protocol 1]; single deep inspiration, positive inspiratory pressure of 15 cm H<jats:sub>2<\/jats:sub>O [protocol 2]; recruitment maneuver [protocol 3]; and hyperventilation, 20 seconds with a positive end-expiratory pressure of 5 cm H<jats:sub>2<\/jats:sub>O [protocol 4]). Thoracic CT was performed for each protocol; images were acquired during apnea for protocols 1 and 3 and during positive airway pressure for protocols 2 and 4. Heart rate; systolic, mean, and diastolic arterial blood pressures; blood gas values; end-tidal isoflurane concentration; rectal temperature; and measures of atelectasis, total lung volume (TLV), and lung density were determined before and after each protocol.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014None of the protocols eliminated atelectasis; the number of lung lobes with atelectasis was significantly greater during protocol 1 than during the other protocols. Lung density and TLV differed significantly among protocols, except between protocols 1 and 3. Protocol 2 TLV exceeded reference values. Arterial blood pressure after each protocol was lower than before the protocols. Mean and diastolic arterial blood pressure were higher after protocol 3 and diastolic arterial blood pressure was higher after protocol 4 than after protocol 2.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Standardization of ventilatory protocols may minimize effects on thoracic CT images and hemodynamic variables. Although atelectasis was still present, ventilatory protocols 3 and 4 provided the best compromise between image quality and hemodynamic stability.<\/jats:p>","DOI":"10.2460\/ajvr.73.5.646","type":"journal-article","created":{"date-parts":[[2012,4,25]],"date-time":"2012-04-25T18:13:49Z","timestamp":1335377629000},"page":"646-653","source":"Crossref","is-referenced-by-count":24,"title":["Comparison of four ventilatory protocols for computed tomography of the thorax in healthy cats"],"prefix":"10.2460","volume":"73","author":[{"given":"Natalia","family":"Henao-Guerrero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Ricco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeryl C.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Buechner-Maxwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory B.","family":"Daniel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Clin Tech Small Anim Pract","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S1096-2867(99)80011-5","article-title":"Alternative imaging of the lung","volume":"14","author":"Schwarz","year":"1999"},{"key":"ref2","series-title":"Probl Vet Med","first-page":"239","article-title":"Diagnostic pulmonary imaging","volume":"4","author":"Tidwell","year":"1992"},{"key":"ref3","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1111\/j.1748-5827.2003.tb00121.x","article-title":"Use of computed tomography in the diseased feline thorax","volume":"44","author":"Henninger","year":"2003"},{"key":"ref4","series-title":"Vet Radiol Ultrasound","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1111\/j.1740-8261.2004.04093.x","article-title":"Computed tomographic evaluation of canine and feline mediastinal masses in 14 patients","volume":"45","author":"Yoon","year":"2004"},{"key":"ref5","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1111\/j.1748-5827.2003.tb00107.x","article-title":"Pulmonary adenocarcinoma with osteoblastic bone metastases in a cat","volume":"44","author":"Nakanishi","year":"2003"},{"key":"ref6","series-title":"Vet Clin North Am Small Anim Pract","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/j.cvsm.2007.05.014","article-title":"Approach to the respiratory patient","volume":"37","author":"Miller","year":"2007"},{"key":"ref7","series-title":"Vet Radiol Ultrasound","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/j.1740-8261.2005.00023.x","article-title":"Use of radiography in combination with computed tomography for the assessment of noncardiac thoracic disease in the dog and cat","volume":"46","author":"Prather","year":"2005"},{"key":"ref8","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1939-1676.2004.tb02580.x","article-title":"Pulmonary thromboembolism in cats","volume":"18","author":"Schermerhorn","year":"2004"},{"key":"ref9","series-title":"J Feline Med Surg","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.jfms.2003.11.006","article-title":"Lower respiratory tract infections in cats: 21 cases (1995\u20132000)","volume":"6","author":"Foster","year":"2004"},{"key":"ref10","series-title":"Vet Clin North Am Small Anim Pract","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/S0195-5616(00)06007-1","article-title":"Feline asthma. 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